A-beta PP/A-beta, Epidemiology, Molecular and Cell biology, Chemistry/Pharmacology, Signal transduction, Clinical trials, Neurobiology
University, Medical hospital, independent
Top Papers unpublished data.
What are the top three papers (not yours) you have read recently? - Craft S. Effects of intranasal insulin on cognition in memory-impaired older adults: Modulation by APOE genotype. Neurobiol Aging. 2005;Jun 15.
-De la Monte SM. Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes?J Alzheimers Dis. 2005;Feb;7(1):6
-Marchesi Vincent T. An alternative interpretation of the amyloid A hypothesis with regard to the pathogenesis of Alzheimer's disease PNAS. 2005;102:9093.
-Cummings J. L. Drug Therapy: Alzheimer's Disease. N Engl J Med. 2004; 351:56.
If resources were not limited, what research projects would you pursue? I am looking for colaboration with a research team in the field of AD: testing new target therapies upstream the "Amyloid cascade".(préclinical level, cellular culture and animal models.)
What is your leading hypothesis? Defective insulin signaling restricted to the brain, in a large sub-group of AD patients.