Top Papers N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.Goñi-Oliver P, Lucas JJ, Avila J, Hernández F.J Biol Chem. 2007 Aug 3;282(31):22406-13. Epub 2007 Jun 14. PMID: 17569662
Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert.Engel T, Goñi-Oliver P, Lucas JJ, Avila J, Hernández F.J Neurochem. 2006 Dec;99(6):1445-55. Epub 2006 Oct 24. PMID: 17059563
Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3. Engel T, Hernández F, Avila J, Lucas JJ. J Neurosci. 2006 May 10;26(19):5083-90. PMID: 16687499