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Researcher Profile - Daniele Zacchetti Get Newsletter
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Home: Community: Researcher Profiles
Researcher Profile

RESEARCHER INFORMATION
First Name:Daniele
Last Name:Zacchetti
Title:Dr
Advanced Degrees:PhD
Affiliation:San Raffaele Scient. Inst.
Department:Dibit
Street Address 1:via Olgettina 58
City:Milano
State/Province:MI
Zip/Postal Code:20132
Country/Territory:Italy
Phone:+39-02-26434817
Fax:+39-02-26434813
Disclosure:
(view policy) 
Member reports no financial or other potential conflicts of interest. [Last Modified: 15 December 2004]
View all comments by Daniele Zacchetti
Clinical Interests:
Alzheimer Disease
Research Focus:
Drug screening, A-beta PP/A-beta, Microscopy, Animal Models, Molecular and Cell biology, Neurobiology, Chemistry/Pharmacology, Clinical trials, Signal transduction
Work Sector(s):
Medical hospital, University, Research institute
Web Sites:
Personal: http://www.sanraffaele.org/research/zacchetti
Professional: http://www.sanraffaele.org
Lab: http://w3dibit.hsr.it/nfc/
Researcher Bio
Born in 1964, Udine, Italy. Married, three children.
* 1989 Degree in Pharmaceutical Chemistry and Technology with honours, Univ. of Milano, Italy
* 1992 PhD in Cellular and Molecular Biology, Univ. of Milano, Italy
* 1992/1994 Junior Scientist, Dibit, San Raffaele Scientific Institute, Milano, Italy
* 1995/1997 Post-doc Fellow, European Molecular Biology Laboratory, Heidelberg, Germany
* 1998/today Staff scientist and Project Leader, Cellular Neurophysiology Unit, Dibit, San Raffaele Scientific Institute
Top Papers
* De Pietri Tonelli D, Mihailovich M, Di Cesare A, Codazzi F, Grohovaz F, and Zacchetti D. (2004) Translational regulation of BACE-1 expression in neuronal and non-neuronal cells. Nucleic Acids Res. 32:1808-1817
* De Pietri Tonelli D, Schnurbus R, Pesole G, Grohovaz F, and Zacchetti D. (2003) Translational control of Scamper expression via a cell-specific internal ribosome entry site. Nucleic Acids Res. 31:2508-2513
* Ehehalt R, Michel B, De Pietri Tonelli D, Zacchetti D, Simons K, and Keller P. (2002) Splice variants of the beta-site APP-cleaving enzyme BACE1 in human brain and pancreas. Biochem. Biophys. Res. Comm. 293:30-37
* Schnurbus R, De Pietri Tonelli D, Grohovaz F, and Zacchetti D. (2002) Re-evaluation of primary structure, topology, and localization of Scamper, a putative intracellular Ca2+ channel activated by spingosylphosphocholine. Biochem. J. 362:183-189
* Benting J, Lecat S, Zacchetti D, and Simons K. (2000) Protein expression in Drosophila Schneider cells. Anal. Biochem. 278:59-68
* Cheong KH, Zacchetti D, Schneeberger EE, Simons K. (1999) VIP17/MAL, a lipid raft-associated protein, is involved in apical transport in MDCK cells. Proc.Natl.Acad.Sci.USA 96:6241-8
* Bertuzzi F, Zacchetti D, Berra C, Socci C, Pozza G, Pontiroli AE, Grohovaz F. (1996) Intercellular Ca2+ waves sustain coordinate insulin secretion in pig islets of Langerhans. FEBS-Lett. 379:21-5
* Zacchetti D, Peranen J, Murata M, Fiedler K, Simons K. (1995) VIP17/MAL, a proteolipid in apical transport vesicles. FEBS-Lett. 377:465-9
* Lorenzon P, Zacchetti D, Codazzi F, Fumagalli G, Meldolesi J, Grohovaz F. (1995) Ca2+ waves in PC12 neurites: a bidirectional, receptor-oriented form of Ca2+ signaling. J. Cell Biol. 129:797-804

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