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Home: Community: Researcher Profiles
Researcher Profile

RESEARCHER INFORMATION
First Name:Salvatore
Last Name:Aloj
Title:Professor
Advanced Degrees:MD
Affiliation:University of Naples Federico II
Department:Cellular & Molecular Biology & Pathology
Street Address 1:Via S. Pansini, 5
City:Napoli
Zip/Postal Code:I-80131
Country/Territory:Italy
Phone:+39-0817463601
Fax:+39-0817463308
Email Address: 
Disclosure:
(view policy) 
Member reports no financial or other potential conflicts of interest. [Last Modified: 13 October 2009]
Clinical Interests:
Neuromuscular Disorders (ALS, etc.), Aging Process, Prion Diseases, Parkinson Disease, Alzheimer Disease
Research Focus:
Apoptosis/Cell cycle, Proteomics, Molecular and Cell biology, Chemistry/Pharmacology, DNA microarrays, Signal transduction, A-beta PP/A-beta, Protein structure/chemistry
Work Sector(s):
University
Web Sites:
Professional: http://www.dbpcm.org/
Top Papers
Beguinot, F., Beguinot, L., Tramontano, D., Duilio, C., Formisano,S., Bifulco, M., Ambesi-Impiombato, F.S., and Aloj, S. M.: Thyrotropin regulation of membrane lipid fluidity in the FRTL-5 thyroid cell line. J. Biol. Chem., 262, 1575-1582 (1987).

Bifulco, M., Spitz, I. M., Hirsh, H. J., Shorer, Z., and Aloj, S. M.: High molecular weight serum thyrotropin revisited. N. Engl. J. Med., 316, 1609-1610 (1987).

Aloj, S. M.: Cholesterol metabolism and growth in FRTL-5 cells.In Ambesi-Impiombato, F.S., and Perrild, H. (Eds): FRTL-5 today. Excerpta Medica International Congress Series 818, 1989, pp.117-119.

Aloj, S. M., Grieco, D., Kohn, A.D., Nikodem, V. M., and Kohn, L. D.: Thyrotropin regulation of malic enzyme in FRTL-5 rat thyroid cells.Mol. Endocrinol., 4, 611-622 (1990).

Bifulco, M., Santillo, M., Tedesco, I., Zarrilli, R., Laezza, C., and Aloj, S. M.: Thyrotropin modulates low density lipoprotein binding activity in FRTL-5 thyroid cells. J. Biol. Chem. 265, 19336-19342 (1990).

Grieco, D., Beg, Z. H., Romano, A., Bifulco, M., and Aloj, S. M.: Cell cycle progression and 3-hydroxy-3-methylglutaryl coenzyme A reductase are regulated by thyrotropin in FRTL-5 rat thyroid cells. J.Biol. Chem. 265, 19343-19350 (1990).

Aloj, S. M., Liguoro D., Kiang, J. G., and Smallridge, R. C.: Purinergic (P2) receptor-operated calcium entry into rat thyroid cells. Biochem. Biophys. Res. Commun. 195,1-7 (1993).

Bifulco M., Perillo, B., Saji, M., Laezza,C., Tedesco, I., Kohn, L. D. and Aloj, S. M.: Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A reductase gene expression in FRTL-5 cells: 1. Identification and characterization of a cyclic-AMP responsive element (CRE) in the rat reductase promoter. J. Biol. Chem. 270, 1523 1 15236 (1995).

Perillo,B., Tedesco, I., Laezza, C., Santillo, M., Romano, A., Aloj, S. M., and Bifulco, M.: Regulation of 3-Hydroxy-3-methylglutarylCoenzyme A reductase gene expression in FRTL-5 cells: 2. Down-regulation by v-K-ras oncogene. J. Biol. Chem. 270, 15237-15241 (1995).

Bifulco, M., Laezza, C., and Aloj, S. M.: Inhibition of farnesylation blocks growth but not differentiation in FRTL-5 thyroid cells. Biochimie 1999 Apr;81(4):287-90
What is the greatest void to date in our knowledge of Alzheimer's Disease?
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