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| First Name: | Luigi | | Last Name: | Puglielli | | Title: | Assistant Professor | | Advanced Degrees: | M.D., Ph.D. | | Affiliation: | University of Wisconsin-Madison | | Department: | Medicine | | Street Address 1: | VAH-GRECC 11G, 2500 Overlook Terrace | | City: | Madison | | State/Province: | WI | | Zip/Postal Code: | 53705 | Country/Territory: | U.S.A. | | Phone: | 608-2561901 | | Fax: | 608-280-7291 | | Email Address: |  |
Disclosure:
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Member reports no financial or other potential conflicts of interest. [Last Modified: 19 February 2004]
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View all comments by Luigi Puglielli
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Alzheimer Disease, Aging Process
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Molecular and Cell biology, Neuropathology, A-beta PP/A-beta, Neurobiology, Signal transduction
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Puglielli, L., Tanzi, R.E., and Kovacs, D.M. Alzheimer’s disease: the cholesterol connection. Nature Neuroscience 2003; 6: 345-351.
Puglielli, L., Konopka, G., Pack-Chung, E., MacKenzie Ingano, L.A., Berezovska, O., Hymam, B.T., Chang, T.Y., Tanzi, R.E., and Kovacs, D.M. Acyl coenzyme-A:cholesterol acyltransferase (ACAT) modulates the generation of the amyloid b-peptide. Nature Cell Biology 2001; 3: 905-912.
Puglielli, L., Ellis, B.C., Saunders, A.J., and Kovacs, D.M. Ceramide stabilizes BACE1 and promotes amyloid b-peptide biogenesis. J. Biol. Chem. 2003; 278: 19777-19783. |
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