Cycloxygenase inhibitors leave too much to be desired. Side effects include: GI,GU, and liver bleeding along with possible vessel hemmorhage that can be fatal. Decrease of inflammatory response many times can be too extreme, while brain inflammation can occur. Fluctuations in blood pressure, too often at the therapeutic doses, can be life threatening. COX inhibitors do not treat AD once a patient has it; it merely shows some correlation with reduced risk, but not well enough in persons with strong genetic risk factors. Inflammation must be reduced, but there must be safer and more effective methods we have not considered.

References:
Scientific American FEB 2005. Encyclopedia of Alzheimers 2004. Fundamentals of Immunology 2004.

View all comments by Jacob Mack

I would probably be against it because I am tired of all these new medications coming out with too many side effects. Side effects that are worse than the condition being treated. If this is the way I have to live my life than so be it.

View all comments by Shannon Ashford

I have an allergic reaction to the drugs. A severe burning and itching sensation occurs in my hands and feet. Unless this could be controlled, I could not take COX-2 Inhibitors.

View all comments by Billie Cox