Antibody

βIII-Tubulin (TUJ1)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG2a
Methods: IH, IP, WB
Source: Covance Research Products, Inc.
Cat# MMS-435P
References:
He, 2009
Marchetto, 2008
Di Giorgio, 2008
Choi, 2008
Breunig, 2007
Romito-DiGiacomo, 2007
Formulation: purified, PBS, thimerosal
Reactivity:
Reacts in: Mammal (various)

Immunogen/Epitope

immunogen = microtubules derived from rat brain

Specificity

highly reactive to neuron specific Class III Beta-tubulin (βIII); does not identify Beta-tubulin found in glial cells.

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References

Paper Citations

  1. . Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease. J Neurosci. 2009 May 20;29(20):6545-57. PubMed.
  2. . Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells. Cell Stem Cell. 2008 Dec 4;3(6):649-57. PubMed.
  3. . Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation. Cell Stem Cell. 2008 Dec 4;3(6):637-48. PubMed.
  4. . Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation. Neuron. 2008 Aug 28;59(4):568-80. PubMed.
  5. . Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20558-63. PubMed.
  6. . Effects of Alzheimer's disease on different cortical layers: the role of intrinsic differences in Abeta susceptibility. J Neurosci. 2007 Aug 8;27(32):8496-504. PubMed.

Further Reading

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