Antibody

VGAT, cytoplasmic

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Clonality: polyclonal
Host: Rabbit
Source: Synaptic Systems
Cat# 131 002
References:
Damiani, 2008
(unspecified epitope)
Ferguson, 2007
Formulation: serum, RSA, lyophilized; also available affinity purified, 131 003
Reactivity:
Reacts in: Human, Monkey, Mouse, Rat
others not tested

Immunogen/Epitope

Immunogen = synthetic peptide AEPPVEGDIHYQR (aa residues 75 - 87 in rat) coupled to KLH

Specificity

Specific for the mammalian vesicular GABA transporter; best and most specific marker for GABAergic synapses

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References

Paper Citations

  1. Damiani D, Alexander JJ, O'Rourke JR, McManus M, Jadhav AP, Cepko CL, Hauswirth WW, Harfe BD, Strettoi E. Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci. 2008 May 7;28(19):4878-87. PubMed.
  2. Ferguson SM, Brasnjo G, Hayashi M, Wölfel M, Collesi C, Giovedi S, Raimondi A, Gong LW, Ariel P, Paradise S, O'Toole E, Flavell R, Cremona O, Miesenböck G, Ryan TA, De Camilli P. A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science. 2007 Apr 27;316(5824):570-4. PubMed.

Further Reading

No Available Further Reading