β-Tubulin (TUB 2.1)

Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Methods: IF
Source: Sigma Aldrich
Cat# C4585
(β tubulin)
Lewis, 2001
Ikeuchi, 2003
(mono tubulin)
Peters, 2002
Formulation: purified, PBS, BSA, azide, Cy3 conj.
Reacts in: Bovine, Rabbit, Frog, Wheat, Human, Hamster, Mouse, Rat, Moth


immunogen = purified rat brain tubulin (epitope in the carboxy-terminal part of β-tubulin between aa 281-446)


reacts with the chymotryptic β-Lc and β-Sc tubulin fragments and doesnot seem to exhibit mouse brain beta tubulin isoform related specificity

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Paper Citations

  1. . Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science. 2001 Aug 24;293(5534):1487-91. PubMed.
  2. . The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage. J Biol Chem. 2003 Mar 7;278(10):7751-4. Epub 2003 Jan 24 PubMed.
  3. . Arfaptin 2 regulates the aggregation of mutant huntingtin protein. Nat Cell Biol. 2002 Mar;4(3):240-5. PubMed.

Further Reading

No Available Further Reading