Methods: DB, WB
Source: anti β-Amyloid oligomers, ADDL
(paper, Zhao W-Q. et al., Northwestern University, Evanston, IL, USA)
Reacts in: Human, Mouse
immunogern = Aβ oligomers (amyloid β-derived diffusible ligands, ADDLs), mixed with Freund's adjuvant
shows weak binding to Alzheimer's disease brain extract but still discriminated between Alzheimer's disease and control brain; shows little to no staining of monomers
- Varvel NH, Bhaskar K, Patil AR, Pimplikar SW, Herrup K, Lamb BT. Abeta oligomers induce neuronal cell cycle events in Alzheimer's disease. J Neurosci. 2008 Oct 22;28(43):10786-93. PubMed.
No Available Further Reading