Source: Covance Research Products, Inc.
Formulation: Purified IgG fraction, PBS; no preservatives or carrier proteins
Reacts in: Human
immunogen = aa residue 32-40 of Amyloid-β 1-40 peptide, conj. to KLH
specific for the C-terminus of Aβ 40; reacts extremely well with the 40 isoform; no cross reaction with Aβ 42 or with APP
- Nitsch RM, Deng M, Tennis M, Schoenfeld D, Growdon JH. The selective muscarinic M1 agonist AF102B decreases levels of total Abeta in cerebrospinal fluid of patients with Alzheimer's disease. Ann Neurol. 2000 Dec;48(6):913-8. PubMed.