Antibody

Tau, truncated, cleavage site 421/422 (Tau-C3)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Methods: IH, IP, WB
Source: Biosource Invitrogen
Cat# AHB0061
Reference:
Spires-Jones, 2008
Formulation: affinity purified ascites, PBS, BSA, azide, unconj.
Reactivity:
Reacts in: Human, Mouse, Rat
others not tested

Immunogen/Epitope

immunogen = KLH- CSSTGSIDMVD, corresp. to the C-terminus of tau truncated at Asp421

Specificity

recognizes tau when truncated at Asp421; no reaction with full-length tau, or with tau truncated at Glu391 or Ala429

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References

Paper Citations

  1. . In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons. J Neurosci. 2008 Jan 23;28(4):862-7. PubMed.

Further Reading

No Available Further Reading