Methods: ELISA, IB
(Gregory Jicha, Departments of Pathology and Neurpscience, Albert Einstein College of Medicine)
Reacts in: Human
immunogen = affinity purified PHF (epitope around phosphor. Ser235)
recognizes tau phosphor. at Ser235; not reactive to non-phosphor. tau.paper Jincha, et al. 1997
- Vingtdeux V, Davies P, Dickson DW, Marambaud P. AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies. Acta Neuropathol. 2011 Mar;121(3):337-49. PubMed.
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