Antibody

α-Synuclein

Tools

Back to the Top

Clonality: polyclonal
Host: Rabbit
Methods: IC, IH, WB
Source: Chemicon and Upstate are Millipore
cat# AB5038
References:
Clinton, 2010
Paleologou, 2010, both, unspecified formulation
Formulation: lyophilized, serum, no preservative
Reactivity:
Reacts in: Human, Rat
others not tested

Immunogen/Epitope

immunogen = peptide seq. N-G I L E D M P V D P D N E A Y E M P S E E C-C, corresp. to human α-synuclein a.a. 111-131 coupled to KLH

Specificity

detects α-synuclein (14-19kDa); the immunizing peptide was chosen to reduce cross-reactivity of AB5038 with β-synuclein to a minimum

Comments / Questions

Make a comment or submit a question

To make a comment you must login or register.

Comments on this content

No Available Comments

References

Paper Citations

  1. . Synergistic Interactions between Abeta, tau, and alpha-synuclein: acceleration of neuropathology and cognitive decline. J Neurosci. 2010 May 26;30(21):7281-9. PubMed.
  2. . Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions. J Neurosci. 2010 Mar 3;30(9):3184-98. PubMed.

Further Reading