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Clonality: monoclonal
Host: Mouse
Source: α-Synuclein nSyn823
(Virginia Lee, University of Pennsylvania, CNDR, Philadelphia, PA)
used in paper by Giasson, 2002
reference:<br />Giasson BI. Duda JE. Murray IV. ... Lee V.M.-Y. Science., 290:985-989, 2000


immunogen = nitrated α-synuclein


nitration specific α-synuclein

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Paper Citations

  1. . Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron. 2002 May 16;34(4):521-33. PubMed.

External Citations

  1. Virginia Lee
  2. CNDR

Further Reading


  1. Fatal Attraction or Beneficial Interaction: Microglia, Aβ and Neurons
  2. Paper Alert—Transcription Factors Regulate Aβ Clearance
  3. Calling for Backup: Microglia from Bone Marrow Fight Plaques in AD Mice
  4. Reykjavik: Science Near the Blue Lagoon
  5. Clearing Aggregates—Macrophages Fall Short for Aβ, but Vaccine Mops Up α-synuclein
  6. Microglia—Medics or Meddlers in Dementia
  7. DC: New Neprilysin Methods Reduce Brain Aβ
  8. DC: Aβ Clearance—Roles for MBP, Transcription Factors?
  9. The Brain and Microglial Recruitment—Think Local, Not Global