Antibody

Spectrin α-I (17C7)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Source: Abcam
Cat# ab11751
Formulation: liquid, PBS, azide, ppt supernatant
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

Immunogen = recombinant α I spectrin (erythroid spectrin) SH3 domain

Specificity

alpha I spectrin SH3 domain; no crossreaction with α II (nonerythroid) spectrin SH3 domain or recombinant human fodrin SH3 domain. In NIH 3T3 cells, reacts with a 200 kDa protein which is a candidate marker of endocytic vesicles called macropinosomes

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