The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

572 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
Tau From labs (22)
Formerly available through Dr. Peter Davies. For updated information, contact antibodies@alzforum.org. monoclonal
IgG2b
Mouse
- Human Human tau 130-150 - -
Formerly available through Dr. Peter Davies. For updated information, contact antibodies@alzforum.org. monoclonal
IgG2b
Mouse
- Human, Mouse, Rat epitope around phospho Threonine 231 tau phospho. at Thr231 -
(Taizo Taniguchi, DirectorBehavioral and Medical Science Research Consortium, Hyogo, Japan) monoclonal
Mouse
(supernate, gel filtered)
- - raised against human tau (epitope = first repeat of MBD, aa 257-274) binds CHO-R3tau and CHO-R4tau; inhibits PHF formation in human tau, completly blocks in vitro 3RMBD and 4RMBD aggregation -
Formerly available through Dr. Peter Davies. For updated information, contact antibodies@alzforum.org. monoclonal
IgG2b
Mouse
- Human, Mouse - tau -
Formerly available through Dr. Peter Davies. For updated information, contact antibodies@alzforum.org. monoclonal
Mouse
- Human, Mouse immunogen = amino acids around phosphorylated Ser214 recognizes human and murine tau phosphorylated at S214 -
Formerly available through Dr. Peter Davies. For updated information, contact antibodies@alzforum.org. monoclonal
IgG3
Mouse
- Human, Mouse immunogen = the synthetic phosphopeptides KSPRHLS(P)NV S(P)STGS(P)ID and KSPRHLS(P)NV SS(P)TGSID recognizes the PKA-dependent phosphorylation of ser409 in tau; immunoreactivity with neurofibrillary pathology in both early and advanced Alzheimer’s disease, but not in normal brain tissue; reacts with only PHF and the tau peptide containing phospho ser409 -
Formerly available through Dr. Peter Davies. For updated information, contact antibodies@alzforum.org. monoclonal
Mouse
- Human, Mouse epitope around phospho Threonine 231 highly specific for tau phospho. at Thr231 -
MC6(Gregory Jicha, Departments of Pathology and Neurpscience, Albert Einstein College of Medicine)References:Vingtdeux, 2010Planel, 2008 monoclonal
Mouse
- Human immunogen = affinity purified PHF (epitope around phosphor. Ser235) recognizes tau phosphor. at Ser235; not reactive to non-phosphor. tau.paper Jincha, et al. 1997 -
TauC3(Vincent L. Cryns, Cell Death Regulation Laboratory, Division of Endocrinology,Metabolism, and Molecular Medicine, Northwestern University, Chicago, IL)Research paperReference: Alonso, 2010 monoclonal
IgG1
Mouse
(purified IgG, HEPES, saline, glycerol.)
- Human immunogen = KLH- C S S T G S I D M V D, corresp. to residues 412-421 at the C-terminus of tau truncated at Asp421 recognizes tau when truncated at Asp421; no reaction with full-length tau, or with tau truncated at Glu391 or Ala429 -
Tau-1(L.I. Binder, Northwestern Univ.)PaperReference: Alonso, 2010 monoclonal
IgG2a
Mouse
- Mouse, Rat   detects Tau that is not phosphorylized at at Ser198/Ser199/Ser202 -
134d(Inge Grundke-Iqbal, Department of Neurochemistry, New YorkState Institute for Basic Research in Developmental Disabilities)research PaperReference: Alonso, 2010 polyclonal
Rabbit
(antiserum)
- Human immunogen = recombinant human Tau410 recognizes tau in a phosphorylation independent manner -
111e(Khalid Iqbal, Department of Neurochemistry, New YorkState Institute for Basic Research in Developmental Disabilities)research PaperReference: Alonso, 2010 polyclonal
Rabbit
(antiserum)
- Human - recognizes total tau and hyperphosphorylated tau from AD brain; no cross with bovine tau -
92e(Inge Grundke-Iqbal, Department of Neurochemistry, New YorkState Institute for Basic Research in Developmental Disabilities)research PaperReference: Alonso, 2010 polyclonal
Rabbit
(antiserum)
- Human - recognizes both phosphorylated and non phosphorylated tau -
Ab708Li Gan, Gladstone Institute of Neurological DiseaseAssistant Professor of NeurologyUniversity of California, San FranciscoReference: Min SW, 2010 polyclonal
IgG2b
Rabbit
- Human, Rat immunogen = a synthetic tau peptide (amino acids 160–182 for 2N4R tau isoform) containing acetylated lysines at positions 163 and 174 and 180 Ab708 specifically recognizes tau acetylated by p300 under cell-free conditions. In HEK293T cells transfected with tau, overexpression of p300 markedly elevatedthe levels of ac-tau detected with Ab708 while the increase in the levels of t-tau was modest, suggesting that Ab708 preferentially recognizes p300-induced ac-tau in cultured cells. Ab708 recognizes human tau acetylated at positions 163, 174, or 180 and possibly other acetylated lysines on tau, but not nonacetylated tau -
9ABLi Gan, Gladstone Institute of Neurological DiseaseAssistant Professor of NeurologyUniversity of California, San FranciscoReference: Min SW, 2010 polyclonal
Rabbit
- Human, Mouse immunogen = the microtubule-binding region aa 264–287 (ENLKHQPGGG VQIINKLDLSNV), which is 100% conserved between mouse and human 9AB recognizes recombinant tau acetylated by GST-p300, but not tau incubated with GST alone, suggesting that 9AB does not cross-react with non-ac-tau. 9AB also preferentially recognizes p300-induced ac-tau in cultured cells. In mouse brains, 9AB detected low levels of ac-tau. Does not recognize nonacetylated recombinant tau -
Philip Dolan, Prothena Biosciences, South San Francisco, CA monoclonal
Mouse
- Mammal (various), Human, Zebra fish, Drosophila, C. elegans immunogen = tau phosphorylated at S262 in KXGS motif of the 4th repeat and/or Ser356 tau phosphorylated at S262 and/or S356 -
Formerly available through Dr. Peter Davies. For updated information, contact antibodies@alzforum.org. monoclonal
IgG1
Mouse
- Human, Mouse epitope at aa102–140 recognizes total tau -
Formerly available through Dr. Peter Davies. For updated information, contact antibodies@alzforum.org. monoclonal
IgM
Mouse
(IC, IF, IH, IP, WB)
- Human Tau phosphorylated at threonine-231; also conformation-sensitive. Tau phosphorylated at threonine-231; also conformation-sensitive. Not reactive to normal tau. The TG3 epitope is expressed in mitotic cells but not in quiescent cells, suggesting that mitotic phosphoepitopes may lead to conformational changes. -
Formerly available through Dr. Peter Davies. For updated information, see AlzAntibodies page linked in Note below. monoclonal
IgG1
Mouse
- Human, Mouse conformation dependent antibody (epitope within aa 312-322) reactivity depends on both the N terminus (amino acids 7–9), and an amino acid sequence of tau (amino acids 313–322) in the third microtubule binding domain. Recognizes neurofibrillary tangles but does not react with FAC1 -
Formerly available through Dr. Peter Davies. For updated information, see AlzAntibodies page linked in Note below. monoclonal
IgM
Mouse
- - Raised against human basal forebrain homogenate. Epitope subsequently determined to include amino acids 2-10 and 312-342 of tau. Recognizes a misfolded conformation of tau. 68 kDa Tau. Stains neuronal components of AD brain specimens but not normal brain specimens. -
Formerly available through Dr. Peter Davies. For updated information, see AlzAntibodies page linked in Note below. monoclonal
IgG1
Mouse
- Human Immunogen: paired helical filaments of tau. Epitope: around serine-396 and serine-404 phosphorylated sites. - -
Formerly available through Dr. Peter Davies. For updated information, see AlzAntibodies page linked in Note below. monoclonal
IgG2b
Mouse
- Human epitope around phospho-serine 202 Detects tau phosphorylated at serine-202. -
Tau From manufacturers (50)
Autogen Bioclear monoclonal
IgG1
Mouse
(liquid, phosphate, saline, BSA, azide)
- Bovine, Cat, Chicken, Human, Monkey immunogen = purified bovine microtuble associated proteins (MAPS) reacts with both phosphorylated and non-phosphorylated Tau proteins and with Tau from Alzheimer paired helical filaments; does not recognize MAP1, MAP2, MAP5 or tubulin -
Biodesign Meridian LifeScience monoclonal
IgM,κ
Mouse
(supernatant with azide)
- Human     -
Fitzgerald polyclonal
Rabbit
(neat serum)
- Human immunogen = neurofibrillary tangle specifically immunostains Neurofibrillary tangles and degeneratingplaque neurites in cases of Alzheimer's Disease, Downs Syndrome, and normalaged individuals -
Innogenetics monoclonal
IgG1
Mouse
(liquid, PBS, sterile filtered, no preservative, affinity purified)
- Human immunogen = human tau40, aa. around phospho.Thr 231 PHF tau and tau in tangles; no cross with unphosphorylated tau -
Chemicon and Upstate are Millipore monoclonal
IgG1
Mouse
(liquid, ascites)
- Bovine, Sheep, Human, Mouse, Rat immunogen = Bovine tau; epitope aa 210-241 tau (phosphorylated and non-phosphorylated isoforms); stains neurofibrillary tangles, neuropil threads and neuritic plaques associated with AD; no cross-reactivity with tubulin or other microtubule proteins -
PROGEN Biotechnik GmbH polyclonal
IgM,κ
Guinea Pig
(stabilized antiserum, azide)
- Human immunogen = N-terminal domain (20 amino acids: MAS LTV KAY LLGKED AAR EI-C) of human p62 protein, coupled to KLH detects human 62 kD (p62) protein, present in intracytoplasmicinclusions (e.g. hyaline bodies) of hepatocellular carcinoma; stains alsoneurofibrillary tangles in the brain of patients suffering fromAlzheimer’s disease -
- monoclonal
IgG1κ
Mouse
(liquid, PBS, sterile filtered, affinity purified)
- Human partially purified human tau, aa. around phosphorylated Serine 202 Recognizes phosphorylated paired helical filament tau. Recognises tau protein phosphorylated at both serine 202 and threonine 205. No cross-reactivity with unphoshorylated tau. -
Diagnostic Biosystems monoclonal
IgG1
Mouse
(liquid, purified Ig fraction, azide)
- Human immunogen = purified bovine microtubule-associated proteins; epitope maps in the middle of tau specific to 45-68 kD proteins identified as tau proteins; does not cross react with tubulin or other MAPs. Reacts with phosphorylated as well as non-phosphorylated forms of tau, and stains human neurofibrillary tangles, neutrophil threads and neurotic plaques associated with Alzheimer’s disease -
Diagnostic Biosystems monoclonal
IgG1
Mouse
(liquid, azide)
- Human immunogen =purified bovine microtubule-associated proteins Tau (45-68 kDa); does not cross react with tubulin or other MAPs; reacts with phospho. as well as non-phospho. forms of tau -
Diagnostic Biosystems polyclonal
Rabbit
(serum, purified Ig fraction, azide)
- Human immunogen = recomb. protein encoding C-terminal part of human tau stains Tau in neurofibrillary tangles, neuropil threads and neuritic plaques; also stains astrocytes and ribosomes -
Affiniti - Biomol polyclonal
IgM,κ
Rabbit
(liquid, antiserum)
- Human immunogen = a peptide derived from residues 387-436, comprising the UBA domain of p62 detects human 62 kD (p62) protein, found in various neurodegenerative conditions, including tauopathies (Alzheimer’s disease, Picks disease, and frontotemporal dementia) and synucleinopathies (Parkinson’s disease, dementia with Lewy body disease and multiple system atrophy) -
Innogenetics kit
Unknown Host
(solid-phase ELISA, uses monoclonal HT7 for capture, AT270 biotinylated for incubation, streptavidin; working range: 25 to 150 pg/mL)
- Human   specific for tau phosphorylated at threonine 181, antigen in cerebrospinal fluid (CSF) -
Biosource Invitrogen polyclonal
Rabbit
(affinity purified Ig, Dulbecco's PBS, BSA, glycerol, unconjugated)
- Human chemically synthesized phosphopeptide derived from theregion of human Tau that contains serine 396. detects tau phosphorylated at serine 396; no cross with non phosphorylated tau -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, Dulbecco’s PBS, BSA, azide, glycerol, unconjugated)
- Human immunogen = chemically synthesized phosphopeptide derived from the region of human Tau that contains serine 396 tau phosphorylated at serine 396 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human tau-derived peptide that is phospho. at serines 199 and 202 tau phosphorylated at serines 199 and 202 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human immunogen = a chemically synthesized phosphopeptide derived from the region ofhuman Tau that contains serine 199 tau phosphorylated at serine 199 -
Biosource Invitrogen polyclonal
Rabbit
(affinity purified Ig)
- Human immunogen = human tau-derived synthetic peptide that is phosphorylated at serine 202 tau phosphorylated at serine 202 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol)
- Human human tau-derived peptide that is phosphorylated at serine 262 tau phosphorylated at serine 262 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at serine 409 tau phosphorylated at serine 409 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at threonine 212 tau, tau phosphor. at threonine 212 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at threonine 217 tau phosphorylated at threonine 217 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at threonine 231 tau phosphorylated at threonine 231 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at serine 404 tau phosphorylated at serine 404 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at serine 400 tau phosphorylated at serine 400 -
Biosource Invitrogen polyclonal
Rabbit
(liquid, purified Ig, PBS, azide)
- Human immunogen = synthetic peptide, corresp. to aa residues 186-201 of human tau protein isoform 6 (GEPPKSGDRSG-pY-SSPG), conj. to KLH via an N-terminal cysteine residue detects both non-phosphor. and p56lck-phosphor. tau -
Biosource Invitrogen polyclonal
Rabbit
(liquid, purified Ig, PBS, azide)
- Human immunogen = synthetic peptide, corresp. to aa residues 384-397 of human tau protein isoform 6 (AKTDHGAEIV-pY-KSP), conj. to KLH via an N-terminal cysteine residue detects both non-phosphor. and p56lck-phosphor. tau -
Biosource Invitrogen polyclonal
Rabbit
(liquid, purified Ig, PBS, azide)
- Human immunogen = synthetic peptide, corresp. to aa residues 384-397 of human tau protein isoform 8 (A K T D H G A E I V -pY- K S P), conjugated to KLH detects both non-phosphor. and p56lck-phosphor. tau -
Biosource Invitrogen polyclonal
Rabbit
(liquid, purified Ig, PBS, azide)
- Human immunogen = synthetic peptide, corresp. to aa residues 186-201 of human tau protein isoform 6 (GEPPKSGDRSG-pY- SSPG), conj. to KLH detects both non-phosphor. and p56lck-phosphor. tau -
Biosource Invitrogen polyclonal
Mouse
(liquid, purified Ig, PBS, azide)
- Human immunogen = synthetic peptide, corresp. to aa residues 21-36 of human tau protein isoform 6 (GDRKDQGG-pY-TMHQDQE), conj. to KLH detects both non phosphor. and p56lck phosphor. tau -
Biosource Invitrogen monoclonal
IgG1
Mouse
(affinity purified ascites, PBS, BSA, azide, unconj.)
- Human, Mouse, Rat immunogen = KLH- CSSTGSIDMVD, corresp. to the C-terminus of tau truncated at Asp421 recognizes tau when truncated at Asp421; no reaction with full-length tau, or with tau truncated at Glu391 or Ala429 -
BD Pharmingen monoclonal
IgG1
Mouse
(aqueous buffered liquid, supernate, affinity purified, azide)
- Rat immunogen = phosphorylation -independent region in the middle of Tau recognizes both phos. and non phos. forms of Tau -
Biosource Invitrogen kit
Unknown Host
(contains:Hu Tau [pT181]Antibody Bead Concentrate;Hu Tau [pT181]Detection Ab Concentrate;Hu Tau [pT181] Standard)
- Human human tau-derived peptide that is phosphorylated at threonine 181 for the measurement of human Tau when phosphorylated at threonine 181 in CSF and tissueculture media -
Pierce Thermo Scientific monoclonal
IgG1κ
Mouse
(frozen liquid, no carrier or preservative, biotin conj.)
- Bovine, Human immunogen = human tau, epitope between aa 159 and 163 tau and PHF tau tau between aa 159-163 -
Chemicon and Upstate are Millipore monoclonal
IgG2a
Mouse
(purified Ig, phosphate buffered, lyophilized)
- Bovine, Human, Rat immunogen = purified denaturated bovine MAPs (epitope at or near a phosphorylated site) binds to all known electrophoretic species of tau in human, rat and bovine brain (one-dimensional SDS-PAGE); there is some unphosphorylated bias with clone PC1C6 as it seem to recognize only dephosphorylated serine sites at 195, 198, 199, and 202 -
Abcam monoclonal
IgG1
Mouse
(liquid, IgG fraction, PBS, azide.For BSA and azide free, see ab80579)
- Human immunogen = purified bovine microtubule associated proteins specific to 45-68 kDa proteins identified as tau proteins; no cross with tubulin or other MAPs; phospho. as well as non-phospho. forms of tau -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at threonine 205 tau phosphorylated at threonine 205 -
Biosource Invitrogen polyclonal
Rabbit
(purified Ig, PBS, BSA, azide, glycerol, unconjugated)
- Human human tau-derived peptide that is phosphorylated at serine 422 tau phosphorylated at serine 422 -
Pierce Thermo Scientific monoclonal
IgG1κ
Mouse
(supernatant, affinity purified, no carrier or preservativeAlso available biotin conj., MN-1050B)
- Human immunogen == partially purified human PHF tau, aa. around phosphorylated Thr181 PHF tau, tamgles and neurofilaments; no cross with recomb. unphospho tau; weak cross with normal tau -
DAKO polyclonal
Ig
Rabbit
(serum, purified Ig fraction, azide)
- Human, Mouse, Rat immunogen = C-terminal part of human tau protein expressed in E. coli; aa. 243-441, contains the four repeated sequences involved in microtubule binding (MTB) reacts with tau protein and with tau from Alzheimer paired helical filaments; also MAP2; well-suited for gel immunoprecipitation techniques -
Biosource Invitrogen polyclonal
Rabbit
(affinity purified Ig, Dulbecco's PBS, BSA, glycerol, unconjugated)
- Human phospho peptide derived from the region of human Tau that contains serine 214 detects tau phosphorylated at serine 204; no cross with non phosphorylated tau -
Pierce Thermo Scientific monoclonal
IgG1κ
Mouse
(serum-free supernatant, affinity purified, no carrier or preservative. Also available Biotin conj, MN-1000B)
- Bovine, Human immunogen = purified human tau, between aa 159 and 163, (PPGQK) tau and PHF tau from human and bovine brain -
Pierce Thermo Scientific monoclonal
IgG1κ
Mouse
(purified, no carrier or preservative)
- Human immunogen = aa. around phosphorylated Thr231 detects Tau doubly phosphorylated at Thr231 and Ser235; weak recognition of phosphorylation at Thr231 only -
Biosource Invitrogen monoclonal
IgG1
Mouse
(ascites, affinity purified BSA, azide, unconj.)
- Cow, Sheep, Human, Mouse, Rat immunogen = purified bovine microtuble associated proteins; epitope in middle region of tau tau proteins ranging from 45-68 kDa, not other MAPs or tubulin; tangles marker; reacts with non-phosphor. and phosphor. tau -
Autogen Bioclear kit
Mouse
(solid-phase enzymeimmunoassay, uses monoclonal AT120 for capture, HT7 and BT2 for incubation, streptavidin)
- Human - tau in cerebrospinal fluid -
Innogenetics monoclonal
Mouse
- Bovine, Human immunogen = purified human tau; (epitope within aa 159-163) phosphorylated and non phosphorylated tau -
Innogenetics monoclonal
IgG1κ
Mouse
(liquid, sterile filtered, PBS, no preservative, affinity purified)
- Human immunogen = human tau40, aa. around phospho. Thr 181 specific for tau phospho at Thr 181; as PHF-tau, tangles and neurofilaments; weak cross with normal tau; -
Innogenetics kit
Mouse
(solid-phase enzymeimmunoassay, uses monoclonal AT120 for capture, HT7 and BT2 for incubation. Streptavidin detection of the antibodies.)
- Human - tau in cerebrospinal fluid -
Synaptic Systems
Cat# 314011
monoclonal
IgG2a

(Purified IgG, lyophilized. Azide was added before lyophilization. Unconjugated.)
- Human, Mouse, Rat Recombinant mouse tau (amino acids 3 - 214) The antibody binds phosphorylated and non-phosphorylated tau proteins. Confirmed available March 2014
Synaptic Systems
Cat# 314 002
polyclonal
Rabbit
(antiserum, lyophilized. )
- Human, Mouse, Rat Recombinant mouse tau (amino acids 3 - 214). The antibody binds phosphorylated and non-phosphorylated tau proteins. Confirmed available March 2014
Pierce Thermo Scientific
Cat#  MN-1020
monoclonal
IgG1κ
Mouse
(Protein A affinity purified, PBS, no preservative)
- Baboon, Human, Rabbit, Hamster, Avian (various), Drosophila immunogen = partially purified human paired helical filament tau. Recognizes tau protein phosphorylated at both serine 202 (Ser202) and threonine 205 (Thr205). Does not cross-react with unphosphorylated forms of tau.   Confirmed available April 2015.