The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

Search tip: To find an exact keyword match, surround your search term by quotation marks, ie. "Ki-67"

Tools

Back to the Top

Antibodies

619 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
Amyloid-β From labs (23)
anti-Aβ38(Pankaj Mehta,Department of Immunology, New York State Institute for Basic Research, Staten Island, New York)Paper: Potempska A, Mack K, Mehta PD, et al. Quantitation of sub-femtomole amounts of Alzheimer amyloid beta peptides. Amyloid: Int J Clin Invest 1999;16:14-21 kit
Unknown Host
(Sandwich ELISAmonoclonal antibody 6E10 (Signet Labs) is used as capture antibodyrabbit antiserum to Aβ38 is used as the detection antibody)
- Human immunogen (detection antibody) = peptide hCys-aminohexoanoyl-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-GlyOH detects amyloid-beta 38; no reaction to Aβ40 or Aβ42 -
αAβC40J. Buxbaum, Mt. Sinai School of Medicine, NewYork, NYPaperReferences:Hashimoto, 2010Lord, 2009Näslund, 2000 polyclonal
Rabbit
(serum)
- Human, Mouse immunogen = peptide corresponding to the 6 Cterminalresidues of Abx-40 and containing N-terminal cysteineresidues, coupled to KLH recognizes amyloid-beta x-40 -
αAβC42J. Buxbaum, Mt. Sinai School of Medicine, NewYork, NYPaperReferences:Hashimoto, 2010Lord, 2009Näslund, 2000 polyclonal
Rabbit
(serum)
- Human, Mouse immunogen = peptide corresponding to the 6 Cterminalresidues of Abx-42 and containing N-terminal cysteineresidues, coupled to KLH recognizes amyloid-beta x-42 -
2964(Jochen Walter,Department of Neurology, University of Bonn, Bonn,Germany)PaperReference: Heneka, 2010 polyclonal
Rabbit
- Human, Mouse immunogen = synthetic Aβ40 detects Aβ -
WO2(Brian O'Nuallain,Graduate School of Medicine, University of Tennessee Medical Center, Knoxville, TN)PaperReference: Villemagne, 2010 monoclonal
IgM
Mouse
- Human, Mouse raised against sonicated amyloid fibrils grown from synthesized Aβ1–40 peptides (epitope at Aβ residues 5–8) detects amyloid-beta fibrils; exhibits Ab binding to fibrils in the presence of a large excess of Aβ(1–40) monomer, suggesting that Ab is directed against conformational epitopes that only exist in the fibril -
- monoclonal
IgM,κ
Mouse
- Human, Mouse raised against sonicated amyloid fibrils grown from synthesized Aβ1–40 peptides (epitope within aa 1-16) detects amyloid-beta fibrils; exhibits binding to fibrils in the presence of a large excess of Aβ(1–40) monomer, suggesting it is directed against conformational epitopes that only exist in the fibril -
G2-11Konrad BeyreutherCenter for Molecular Biology Heidelberg (ZMBH), University of HeidelbergPaperReference: Villemagne, 2010 monoclonal
Mouse
(liquid, purified, PBS, BSAAlso see Chemicon MABN12)
- Human, Mouse immunogen = synthetic peptide corresponding to Aβ42, aa. 35-42 (MVGGVVIA), conjugated with KLH or BSA through a cysteine residue added at the N terminus of the peptides recognizes Amyloid β42 at the C-terminus -
G2-10Konrad BeyreutherCenter for Molecular Biology Heidelberg (ZMBH), University of HeidelbergPaperReference: Villemagne, 2010 monoclonal
Mouse
(liquid, purified, PBS, BSAAlso see Chemicon MABN11)
- Human, Mouse immunogen = synthetic peptide corresponding to Aβ40, aa. 33-40 (GLMVGGVV), conjugated with KLH or BSA through a cysteine residue added at the N terminus of the peptides recognizes Amyloid β40 at the C-terminus -
amyloid-beta R165(Pankaj Mehta,Department of Immunology, New York State Institute for Basic Research, Staten Island, New York)References: Chung, E, 2010Schupf, 2008Sigurdsson, 2001 polyclonal
Rabbit
(Sandwich ELISA)
- -   amyloid-beta 42 -
amyloid-beta R162(Pankaj Mehta,Department of Immunology, New York State Institute for Basic Research, Staten Island, New York)References: Chung, E, 2010Schupf, 2008Sigurdsson, 2001 polyclonal
Unknown Host
(Sandwich ELISA)
- -   amyloid-beta 40 -
anti-amyloid beta FCA3340(Frédéric Checler,Centre National de la Recherche Scientifique),PaperReference: Gandy, 2010 polyclonal
Rabbit
- Human, Mouse immunogen = synthetic octapeptide Cys-GLMVGGVV, mimicing the C-terminal end of Aβ 40, coupled to either BSA or KLH amyloid-beta 40; labels leptomeningeal and cortical arterioles;little or no cross with Aβ 42 -
FCA3542(Frédéric Checler,Centre National de la Recherche Scientifique),PaperReferences:Gandy, 2010Lesné, 2006 polyclonal
Rabbit
(serum)
- Human, Mouse immunogen = synthetic octapeptide Cys-MVGGVVIA, mimicing the C-terminal end of Aβ 42, coupled to either BSA or KLH recognizes amyloid-beta 42; little or no cross with Aβ 40; intensely labels both diffuse and mature lesions -
JRF/rAβ/2 (Paul Mathews, New York University, School of Medicine,Center for Dementia Research)Research paperReference: Boland, 2010 monoclonal
Mouse
(liquid, horseradish peroxidase conj.)
- Mouse immunogen = a peptide corresponding to murine Aβ residues 1–15 (DAEFGHDSGFEVRHQ) recognizes mouse but not human Aβ1–40 or Aβ1–42 -
JRF/Aβtot/17(Paul Mathews, New York University, School of Medicine,Marc Merken,Johnson & Johnson Pharm. R&D,paper)References:Gandy, 2010Trinchese, 2008Mi, 2007 monoclonal
Mouse
- Human immunogen = human Aβ1-40 amyloid-beta, binds within residues 1-15 -
JRF/rAβ1-15/2(Paul Mathews, New York University, School of Medicine,Marc Merken,Johnson & Johnson Pharm. R&D,paper)References:Gandy, 2010 monoclonal
Mouse
- Mouse epitope within residues 1-15 of mouse Aβ binds to amyloid-beta -
JRF/cAβ40/10(Paul Mathews, New York University, School of Medicine,Marc Mercken,Johnson & Johnson Pharm. R&D,Paper)References:Boland, 2010Trinchese, 2008Mi, 2007Razmahel, 2002 monoclonal
Mouse
- Human, Mouse immunogen = a peptide corresponding to Aβ residues 36–40 (VGGVV) recognizes the carboxyl terminus of Aβ40; does not detect Aβ1–42 by ELISA or WB, or full-length APP by IP or WB -
JRF/cAβ42/26(Marc Mercken,Johnson & Johnson Pharm. R&D,Paper)References:Boland, 2010Trinchese, 2008Mi, 2007Razmahel, 2002 monoclonal
Mouse
- Human, Mouse immunogen = the carboxy terminal 10 residues of Ab1-42 amyloid-beta 42, C-terminus -
(Konrad Beyreuther, Center of Molecular Biology, University of Heidelberg, Heidelberg, Germany)PaperReference: Kuhn, 2010 monoclonal
IgG2a
Mouse
- Human, Guinea Pig immunogen = decapeptides overlapping each other by one aminoacid, covering residues 1-42 of Aβ (epitope mapping corr. to amino acid residues 4-10 of human Aβ-peptide) High affinity to Amyloid peptides Aβ 1-38, Aβ 1-39, Aβ 1-40 -
3552(Harald Steiner,Laboratory for Alzheimer’s and Parkinson’s Disease Research, Adolf ButenandtInstitute, Ludwig Maximilians University, Munich, Germany)PaperReference: Kuhn, 2010 polyclonal
Unknown Host
- Human immunogen = Aβ1–40 recognizes amyloid-beta -
A11(paper comparing A11 and OC antibodies;source paper for A11; Charles G Glabe, University of California, Irvine)References:Lefterov, 2010 polyclonal
Rabbit
(serum)
- Human immunogen = soluble Amyloid oligomers generic epitope common to prefibrillar oligomers and not fibrils, monomers or natively folded precursor proteins. Stains small focal or punctuate deposits in AD tissue does not stain diffuse plaques or other plaque types. Stains Aβ and polyQ prefibrillar oligomers. -
OC(paper on antibodies;paper on oligimerization; Charles G Glabe, University of California, Irvine)References:Lefterov, 2010Clinton, 2010Blurton-Jones, 2009 polyclonal
Rabbit
(serum)
- Human immunogern = a morphologically homogeneous population of Aβ42 fibrils specifically recognizes fibrils, but not random coil monomer or prefibrillar oligomers; also recognizes 100,000 × G soluble fibrillar oligomers ranging in size from dimer to greater than 250 kDa on western blots. The fibrillar oligomers recognized by OC are immunologically distinct from prefibrillar oligomers recognized by A11, even though their sizes overlap broadly -
IC16(Claus U. Pietrzik,Institute of Physiological Chemistry and Pathobiochemistry, MolecularNeurodegeneration, Johannes-Gutenberg-University Mainz, Mainz, Germany)paper)Reference: Richter L, 2010 monoclonal
Mouse
- Human immunogen = synthetic human Ab peptide 1–16, cross-linked to keyhole limpet hemocyanin recognizes residues 1-16 of Amyloid β. Hybridoma cells were generated by standard procedures and screened for recognition of HSA cross-linked to Ab 1-16by ELISA; recognition of synthetic Ab 1–42 ona standardized dot blot procedure was confirmed and the epitope mapped to Ab 1–8 using a peptide array spanning the entire sequence of Ab -
BAP-17(Manfred Brockhaus, F. Hoffmann-La Roche Ltd., Basel,Paper) monoclonal
IgG1
Mouse
(purified from spent hybridoma medium and conjugated to horseradish peroxidase)
- Human immunogen = the peptide CMVGGVV conjugatedto keyhole limpet hemocyanin specific for Aβ40; no cross-reactivity observed with Ab39, Ab42 or Ab43. Ab41 showed a signal accounting for about10% of the cognate Ab40 signal -
Amyloid-β From manufacturers (76)
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 42 Antibody 4G8, protocol)
- Human, Mouse, Rat - reactive to beta Amyloid 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 42 Antibody 4G8, protocol)
- Human, Mouse, Rat - reactive to human beta Amyloid 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 42 Antibody 4G8, protocol)
- Human, Mouse, Rat - reactive to beta Amyloid 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 42 Antibody 4G8, protocol)
- Human, Mouse, Rat - reactive to human beta Amyloid 42 peptide -
Chemicon and Upstate are Millipore monoclonal
IgG1
Mouse
(liquid, supernatant, azide)
- Bovine, Human, Monkey immunogen = amyloid-β 1-16 conjugated to KLH amyloid-β 1-16 -
Chemicon and Upstate are Millipore monoclonal
IgG2a, κ
Mouse
(liquid, Tris-glycine saline, azide, protein G purified)
- Human, Mouse immunogen = human beta amyloid peptide (epitope at aa 4-10) recognizes amino acid residues 4-10 of human Amyloid β, can also show 120 and 105 kDa APP proteins, and ~45 kDa oligomers of amyloid proteins on our western blot of human Alzheimer diseased brain lysate -
Genetics Company, Inc. monoclonal
IgG2a
Mouse
(biotinylated supernatant IgG, stabilizing solution, no azide, affinity purified)
- Human N-terminal: Epitope mapping corr. to amino acid residues 4-10 of human Aβ-peptide High affinity to Amyloid peptides Aβ 1-38, Aβ 1-39, Aβ 1-40, Aβ 1-43 and Aβ 1-44 -
Genetics Company, Inc. monoclonal
IgG2a
Mouse
(peroxidase, supernatant IgG, stabilizing solution, no azide, affinity purified)
- Human N-terminal: Epitope mapping corr. to amino acid residues 4-10 of human Aβ-peptide High affinity to Amyloid peptides Aβ 1-38, Aβ 1-39, Aβ 1-40, Aβ 1-43 and Aβ 1-44 -
BioLegend monoclonal
IgG1
Mouse
(liquid, no preservatives or carrier proteins, purified)
- Human epitope lies within amino acids 1-8 of the β-Amyloid protein reacts to N-terminal aa 1-8 of β-Amyloid peptide and β-amyloid form of APP Available from BioLegend
Wako Chemicals kit
Mouse
(96 tests:BAN50/BA27(Fab') antibodies from Takeda Chemical Industries.range: 1.0~100 pmol/L)
- Human   Aβ (1-40); detects the N-terminal of Aβ -
Wako Chemicals kit
Mouse
(96 tests:BAN50/BA27(Fab')2, HRP conj. antibodies from Takeda Chemical Industries.range: 1.0~100 pmol/L.Achieved stable antigen-antibody reaction)
- Human achieves more stable antigen-antibody reactions by using F(ab' )2 fragment of the labeled antibody BA27, which recognizes the C-terminal of beta Amyloid 40, while the nonspecific binding is remaining to be reduced Aβ (1-40); detects the C-terminal -
Wako Chemicals kit
Mouse
(96 tests:BAN50/BC05(Fab') HRP conj. antibodies from Takeda Chemical Industries.range: 1.0~100 pmol/L.)
- Human   detects C-terminal of Aβ 42 -
Wako Chemicals monoclonal
Mouse
(50 tests: This kit stains Aβ40 or Aβ42 in tissue section bythe monoclonal antibodies that detects the portionof C-terminal of Aβ.)
- -   distinctive staining of Aβ(1-40) and Aβ(1-42) plaques -
Wako Chemicals kit
Mouse
(96 tests:BNT77/BA27(Fab') HRP conj. antibodies from Takeda Chemical Industries.range: 1.0~100 pmol/L)
- Human, Mouse, Rat BNT77: Specifically detects the Aβ (11-28) of AβBA27: Specifically detects the C-terminal of Aβ 40 detects Aβ (x-40), with a truncated or modified N-terminus -
None monoclonal
IgG1
Mouse
(liquid, PBS, no preservatives or carrier proteins, purified, HRP conj.)
- Human epitope = lies within aa 3-8 of the β-amyloid peptide (EFRHDS) reactive to aa 1-16 of β-Amyloid (precursor forms as well as abnormally processed isoforms Discontinued
Invitrogen Corporation polyclonal
Rabbit
(liquid, affinity purified, rabbit polyclonal immunoglobulins in phosphate buffer, pH 7.4. Carrier and preservative free)
- Human immunogen = synthetic peptide derived from amino acids 36-42 within the carboxyl-terminus region of human β-Amyloid protein Reacts with human Aβ42. No significant cross-reactivity to Aβ40 or Aβ43 has been observed -
Invitrogen Corporation polyclonal
Rabbit
(liquid, affinity purified, rabbit polyclonal immunoglobulins in phosphate buffer, pH 7.4. Carrier and preservative free)
- Human immunogen = synthetic peptide derived from amino acids 34-40 within the carboxyl-terminus region of human β-Amyloid protein Reacts with human Aβ40. No significant cross-reactivity to Aβ42 or Aβ43 has been observed -
Invitrogen Corporation polyclonal
Rabbit
(liquid, affinity purified, rabbit polyclonal immunoglobulins in phosphate buffer, pH 7.4. Carrier and preservative free.Any reactivity to Aβ40 or Aβ42 eliminated through a series of preabsorption steps)
- Human - Reacts with human Aβ43. No significant cross-reactivity to Aβ40 or Aβ42 -
Invitrogen Corporation polyclonal
Rabbit
(liquid, affinity purified, PBS, azide.Any reactivity to Aβ40 or Aβ42 eliminated through a series of preabsorption steps.Biotin conj.)
- Human, Mouse, Rat - Reacts with human Aβ42. No significant cross-reactivity to Aβ1-40 or Aβ1-43 has been observed -
Invitrogen Corporation polyclonal
Rabbit
(Processed whole rabbit serum, azide.can routinely be used without further purification)
- Human immunogen = synthetic peptide corresponding to aa sequence 1-14 (DAEFRHDSGYEVHH) of the human amyloid β protein recognizes Amyloid β; will discriminate amyloid β from other CNS amyloids -
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, purified)
- Rodent (various) - recognizes sequence of Aβ, β-CTF, sAPP-α, and full length APP; negligible cross reactivity with human isoforms of APP and beta amyloid. Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative or carrier protein, affinity G purified)
- Human, Mouse - reactive to the C-terminus of beta amyloid and specific for the isoform ending at the 40th amino acid Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative or carrier protein, biotin conj.)
- Human, Mouse epitope = lies within amino acids aa3-8 of beta amyloid (E F R H D S) reactive to the C-terminus of beta amyloid and specific for the isoform ending at the 43rd amino acid Available from BioLegend
None polyclonal
IgG1
Rabbit
(liquid, PBS, no preservative or carrier protein, affinity G purified)
- Human, Mouse immunogen = peptide conj. to KLH. specific for the C-terminus of Aβ 42; reacts extremely well with the 42 isoform; no cross-reaction with Aβ 40 or APP Discontinued
None polyclonal
IgG1
Rabbit
(liquid, PBS, glycerol, no preservative or carrier protein, affinity G purified, conj. biotin)
- Human, Mouse immunogen = peptide conj. to KLH. specific for the C-terminus of Aβ 42; reacts extremely well with the 42 isoform; no cross-reaction with Aβ 40 or APP Discontinued
None polyclonal
IgG1
Rabbit
(liquid, PBS, glycerol, no preservative or carrier protein, conj. biotin)
- Human, Mouse immunogen = peptide conj. to KLH. specific for the C-terminus of Aβ 42; reacts extremely well with the 42 isoform; no cross-reaction with Aβ 40 or APP Discontinued
None polyclonal
Rabbit
(serum)
- Human - recognizes Amyloid beta 1-40; some (minimal) cross-reactivity to Amyloid beta 1-42 Discontinued
None polyclonal
Rabbit
(affinity purified, PBS, BSA, thimerosol)
- Dog, Human, Chicken - recognizes Amyloid beta 1-42 and 1-40 Discontinued
None polyclonal
Rabbit
(serum)
- Human - recognizes Amyloid beta 1-42; some (minimal) cross-reactivity to Amyloid beta 1-40 Discontinued
None kit
Unknown Host
(Chemiluminescent sandwich ELISA Kit: Capture Antibody Coated Plate; HRP Detection Antibody, chemiluminescent substrate)
- Human - specific for the 1-42 isoform of beta amyloid; has negligible cross reactivity with the 1-40 isoform of beta amyloid Discontinued
BioLegend kit
Unknown Host
(Colorimetric sandwich: Capture Antibody Coated Plate; HRP Detection Antibody; TMB substrate)
- Human, Rodent (various) - specific for the x-42 isoform of beta amyloid; negligible cross reactivity with the x-40 isoform of beta amyloid Available from BioLegend
None monoclonal
IgG2a
Mouse
(liquid, ascites)
- Human immunogen = beta-amyloid (epitope at amino terminus,aa 1-11) recognizes the Amyloid beta (Aß) 1-11 of the human beta amyloid peptide; also recognizes full length APP, sAPP species excluding sAPPß, C99 and Aß Discontinued
None kit
Unknown Host
(Chemiluminescent sandwich ELISA Kit: Capture Antibody Coated Plate; HRP Detection Antibody, chemiluminescent substrate)
- Human, Rodent (various) - specific for the x-42 isoform of beta amyloid; has negligible cross reactivity with the x-40 isoform of beta amyloid Discontinued
None kit
Unknown Host
(Chemiluminescent sandwich ELISA Kit: Capture Antibody Coated Plate; HRP Detection Antibody, chemiluminescent substrate)
- Human - reactive to Aβ; specific for the 1-40 isoform of beta amyloid; has negligible cross reactivity with the 1-42 isoform of beta amyloid Discontinued
None kit
Unknown Host
(sandwich ELISA kit: capture, primary and secondary antibody-HRP)
- - - reactive to Aβ 1-40 Discontinued
None kit
Unknown Host
(Sandwich ELISA Kit: Coated Capture Antibody; Primary Antibody; Secondary Antibody-HRP)
- - - specific for Aβ 1-42 Discontinued
None kit
Unknown Host
(Chemiluminescent sandwich ELISA Kit: Capture Antibody Coated Plate; HRP Detection Antibody, chemiluminescent substrate)
- Human, Rodent (various) - reactive to the x-40 isoform of beta amyloid; has negligible cross reactivity with the x-42 isoform of beta amyloid Discontinued
BioLegend kit
Unknown Host
(Colorimetric sandwich ELISA Kit: Capture Antibody Coated Plate; HRP Detection Antibody; TMB substrate)
- Human, Rodent (various) - reactive to Amyloid β x-40; negligible cross reactivity with the x-42 isoform of beta amyloid Available from BioLegend
Genetics Company, Inc. kit
Unknown Host
(Solid phase sandwich ELISA test, detection range of 25-500pg/ml, low sampla volumes)
- Human, Guinea Pig, Mouse Monoclonal detection and capture antibodies selective determination ofhuman Amyloid b40 (hAb40) in brain samples and for other tissue samples.; reliable, quantitative determination of human Amyloid b40 peptides in brain homogenates. -
Genetics Company, Inc. kit
Unknown Host
(Solid phase sandwich ELISA test, detection range of 25-500pg/ml, low sampla volumes)
- Human, Guinea Pig, Mouse Monoclonal detection and capture antibodies selective determination ofhuman Amyloid b42 (hAb42) in brain samples and for other tissue samples.; reliable, quantitative determination of human Amyloid b42 peptides in brain homogenates. -
Genetics Company, Inc. kit
Unknown Host
(Solid phase sandwich ELISA test, detection range of 100-2000pg/ml)
- Human Monoclonal detection and capture antibodies Aβ 40 in CSF; not Aβ 1-38, Aβ 1-39, Aβ 1-42, Aβ 1-43 or Aβ 1-44 -
Genetics Company, Inc. kit
Unknown Host
(Solid phase sandwich ELISA test, detection range of 100-2000pg/ml)
- Human Monoclonal detection and capture antibodies Aβ 42 in CSF; not Aβ 1-38, Aβ 1-39, Aβ 1-40; low cross reactivity with Aβ 1-43 (13%), Aβ 1-44 (10%) -
Biosource Invitrogen polyclonal
Rabbit
(affinity purified serum, PBS, carrier and preservative free, unconj.)
- Human, Mouse, Rat   specific to Amyloid β42; not Amyloid β40 or Amyloid β43 -
None monoclonal
IgG1
Mouse
(liquid, PBS; no preservatives or carrier proteins)
- Human epitope lies within amino acids 3-8 of the beta Amyloid peptide (E F R H D S) reactive to amino acid residue 1-16 of beta amyloid.; reacts to the abnormally processed isoforms, as well as precursor forms Discontinued
Chemicon and Upstate are Millipore polyclonal
Rabbit
(liquid, tris, BSA, azide, affinity purified)
- Human, Mouse immunogen = a 6 aa peptide sequence from the C-terminal of human β-amyloid 1-42. β-amyloid 1-42 -
Wako Chemicals kit
Mouse
(96 tests:BNT77/BA27(Fab') HRP conj. antibodies from Takeda Chemical Industries.range: 1.0~100 pmol/L.)
- Human, Mouse, Rat   detects C-terminal of Aβ 40 -
Wako Chemicals kit
Mouse
(96 tests: BNT77/BC05(Fab') HRP conj. antibodies from Takeda Chemical IndustriesDetection sensitivity of the kits isabout 10 times higher than that of the conventional products and the dynamic range is from 0.1 to 20.0 pmol/L. Fab' fragment of the labeled antibody is used as well so that the nonspecific binding is reduced)
- Human, Mouse, Rat BNT77: Specifically detects the Aβ (11-28) of AβBC05: Specifically detects the C-terminal of Aβ 42 detects Aβ (1-42) and Aβ (x-42) -
Upstate and Chemicon are Millipore kit
Unknown Host
(AB1518SP anti-neurofibrillary tangles; MAB1561SP anti-amyloid, beta, juxtamembrane EC domain, clone 4G8; MAB5206SP anti-amyloid, beta 1-16, clone DE2)
- - 3 antibodies in package detects amyloid beta -
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative or carrier proteins, protein G purified IgG)
- Human, Mouse - reactive to C-terminus of Amyloid β and specific for the isoform ending at the 42nd amino acid Available from BioLegend
Chemicon and Upstate are Millipore monoclonal
IgG2b
Mouse
(liquid, purified, buffer, Tris-glycine, BSA, azide)
- Human, Mouse immunogen = linear peptide of human Amyloid β40 at the C terminus recognizes Amyloid β40 at the C-terminus -
Stressgen Enzo Life Sciences monoclonal
IgG2b
Mouse
(PBS, glycerol, azide, protein A purified)
- Human, Mouse immunogen = synthetic peptide derived from sequence near the amino-terminus of human Amyloid β Amyloid β (4-5kDa), N-terminal of β-Amyloid 40/42; no reaction with recombinant APP -
Stressgen Enzo Life Sciences monoclonal
IgG1
Mouse
(purified, PBS, azide, PEG, sucrose, lyophilized)
- Human immunogen = C-terminal peptide conjugated to KLH; C-Terminus of Amyloid beta-A4 (1-40) reactive to C-terminus of Amyloid β 1-40; does not cross-react with Amyloid β (1-42) -
Stressgen Enzo Life Sciences monoclonal
IgG1
Mouse
(purified, PBS, azide, PEG, sucrose, lyophilized)
- Human immunogen = C-terminal peptide conjugated to KLH; C-Terminus of Amyloid beta-A4 (1-42) reactive to C-terminus of Amyloid β 1-42; no cross-reaction with Amyloid β (1-40) -
Stressgen Enzo Life Sciences monoclonal
IgG1
Mouse
(lyophilized, purified, PBS, azide, PEG, sucrose)
- Human immunogen = C-terminal peptide conjugated to KLH; C-Terminus of Amyloid beta-A4 (1-40, 1-42) Amyloid β 40/42; cross reacts with APP -
Stressgen Enzo Life Sciences monoclonal
IgG2a, κ
Mouse
(liquid, PBS, azide, protein A/G affinity purified)
- Human immunogen = human amyloid beta-peptide aa 5-16, R H D S G Y E V H H Q K, coupled to carrier Amyloid β (5-16) -
Stressgen Enzo Life Sciences monoclonal
IgG2a, κ
Mouse
(liquid, PBS, azide, protein A/G affinity purified)
- Human immunogen = human amyloid beta-peptide aa 5-16, R H D S G Y E V H H Q K, coupled to carrier recognizes Amyloid β -
Stressgen Enzo Life Sciences monoclonal
IgG2a, κ
Mouse
(liquid, PBS, azide, protein A/G affinity purified)
- Human immunogen = human amyloid beta-peptide aa 5-16, R H D S G Y E V H H Q K, coupled to carrier Amyloid β -
Stressgen Enzo Life Sciences monoclonal
IgG1, κ
Mouse
(liquid, PBS, azide, protein A/G affinity purified)
- Human immunogen = synthetic human amyloid beta-peptide aa 5-16, R H D S G Y E V H H Q K, coupled to carrier amyloid beta -
DAKO
Cat# M0872
monoclonal
IgG1κ
Mouse
(Cell culture supernatant dialysed against 50 mmol/L Tris/HCl, pH 7.2, and containing 15 mmol/L NaN3)
- Human immunogen = synthetic peptide consisting of residues 8-17 Aβ with additional C-terminal cysteine coupled to keyhole limpet hemocyanin (KLH) via the cysteine residue Targets extracellular β-amyloid in human brain parenchyma and cerebral vessels. Confirmed available June 2015
Genetics Company, Inc. monoclonal
IgG2b
Mouse
(affinity purified IgG, PBS, azide)
- Dog, Human, Guinea Pig, Mouse, Rat, Cynomolgus C-terminal epitope mapping corr. to amino acid residue 31-40 of human Aβ peptide recognizes Aβ-peptide, aa 31-40; selective for C-terminal of Aβ- 1-40; not Aβ 1-38, Aβ 1-39, Aβ 1-42, Aβ 1-43 or Aβ 1-44 -
BioLegend monoclonal
IgG1
Mouse
(liquid, protein-A purified, PBS, no preservative or carrier proteins, AlexaFluor® labeled)
- Human the epitope lies within amino acids 4-9 of beta amyloid (FRHDSG) reactive to aa 1-17 Aβ reacts to the abnormally processed isoforms, as well as precursor forms Available from BioLegend
Biosource Invitrogen kit
Unknown Host
(solid phase sandwich ELISA, capture and (same) detection antibody, SAV-HRP, colorimetric.sensitivity of this assay is )
- Human - Recognizes aggregated Aβ in homogenates, ventricular fluid, CSF, tissue culture supernatant, and buffered solution samples -
Biosource Invitrogen polyclonal
Ig
Rabbit
(liquid, affinity purified, PBS, azide)
- Human immunogen = synthetic molecular mimic of soluble oligomers A11 recognizes amino acid sequence independent oligomers of proteins and peptides, including Aβ40 and Aβ42; not monomers or mature fibers of proteins or peptides -
Acanthus Research polyclonal
IgG1
Rabbit
(liquid, serum)
- Human, Mouse immunogen = synthetic peptide corresp. to 1-8 amino acid residuesfrom N-terminus of human Amyloid Betaprotein, conjigated with a carrier protein reactive to the N-terminal region (a.a. residues 1-8) ofAmyloid Beta peptide -
Acanthus Research monoclonal
IgG1
Mouse
(liquid, ascites, azide free)
- Human, Mouse, Rat immunogen = (3-8) N-terminal pyroglutamated synthetic amyloid beta peptide conjigated with a carrier protein reactive to N-terminal truncated Ab starting with pyroglutamate (pGlu, pE) -
IBL kit
Unknown Host
(solid phase sandwich ELISA using 2 kinds of high specific antibodies, range of 12.5 pg/ml ~ 800 pg/ml. Precoated plate with Aβ(38-42) Rabbit IgG; labeled antibody Anti-Human Aβ(11-28) Mouse IgG)
- Human - quantitative determination of human A β (1-42) in cerebrospinal fluid, cellculture media or the extract from brain tissue, both recombinant and native forms of human Aβ(1-42) -
IBL kit
Unknown Host
(solid phase sandwich ELISA, using 2 kinds of highly specific antibodies; range of 7.8 pg/ml ~ 500 pg/ml. Precoated plate with monoclonal 1A10, and labeled antibody 12B2)
- Human - quantitative determination of human Aβ(1-40) in EDTA-plasma, cerebrospinal fluids, serum, cell culture media or the extract from brain tissue; both recombinant and native forms of human Aβ(1-40), and little cross with (1-42) or (1-43) -
Wako Chemicals kit
Mouse
(96 tests:BNT77/BA27(Fab')2, HRP conj. antibodies from Takeda Chemical Industries.range: 1.0~100 pmol/L.Achieved stable antigen-antibody reaction)
- Human, Mouse, Rat achieves more stable antigen-antibody reactions by using F(ab' )2 fragment of the labeled antibody BA27, which recognizes the C-terminal of beta Amyloid 40, while the nonspecific binding is remaining to be reduced detects the C-terminal of Aβ (1-40) and Aβ (x-40) -
Wako Chemicals kit
Mouse
(96 tests: BNT77/BC05(Fab') HRP conj. antibodies from Takeda Chemical Industries. range: 1.0~100 pmol/L)
- Human, Mouse, Rat BNT77: Specifically detects the Aβ (11-28) of AβBC05: Specifically detects the C-terminal of Aβ 42 detects Aβ (1-42) and Aβ (x-42) -
Innogenetics kit
Mouse
- Human Uses 21F12 as a capture antibody and incubation with biotinylated 3D6; 3D6 selectively binds Aß peptides with a free aminogroup at Asp1 (epitope 1–5) amyloid beta (cerebrospinal fluid) -
Biosource Invitrogen monoclonal
IgG
Rabbit
(liquid, PBS, azide)
- Human, Mouse immunogen = peptide (VGGVVIA) corresp. to aa707-713 of P05067 specific to Amyloid β1-42; not Amyloid β1-40, Amyloid β1-43, Amyloid β1-37 or Amyloid β1-38 -
Biosource Invitrogen monoclonal
IgG
Rabbit
(liquid, PBS, azide, protein A purified)
- Human immunogen = aa residues from the C-terminus of human amyloid beta A4 protein specific to Amyloid β42; no cross reaction with Amyloid beta 1-40 -
- monoclonal

(supernat, RIA screened, HPLC purified)
- - immunogen = synthetic peptide fragment derived from different regions of amyloid-beta and coupled to a carrier protein amyloid-beta -
Genetics Company, Inc. monoclonal
IgG2b
Mouse
(liquid, supernatant, stabilizing solution, affinity purified, conj. HRP)
- Dog, Human, Guinea Pig, Mouse, Rat, Cynomolgus C-terminal epitope mapping corr. to amino acid residues 31-40 of human Aβ peptide recognizes Aβ-peptide, aa 31-40; selective for C-terminal of Aβ 1-40; not Aβ 1-38, Aβ 1-39, Aβ 1-42, Aβ 1-43 or Aβ 1-44 -
Genetics Company, Inc. monoclonal
IgG1
Mouse
(liquid, stabilizing solution, no azide, affinity purified, conj. HRP)
- Dog, Human, Guinea Pig, Mouse, Rat, Cynomolgus immunogen = Aβ 1-42 peptide at the C-terminus C-terminal of Aβ 1-42 peptide; not Aβ 1-38, Aβ 1-39, Aβ 1-40; low cross reactivity to Aβ 43 (10%)and Aβ 44 (13%) -
Genetics Company, Inc. monoclonal
IgG2a
Mouse
(supernatant IgG, Tris, azide, affinity purifiedAlso available Biotin or peroxidase conjugated)
- Human N-terminal: Epitope mapping corr. to amino acid residues 4-10 of human Aβ-peptide High affinity to the N-terminal of human Amyloid β peptides Aβ 1-38, Aβ 1-39, Aβ 1-40, Aβ 1-43 and Aβ 1-44 -
Amyloid-β, APP, APLP, AICD From manufacturers (1)
BioLegend monoclonal
IgG2b
Mouse
(biotinylated IgG, PBS, no preservatives or carrier proteins)
- Human, Mouse the epitope lies within amino acids 18-22 of beta amyloid (VFFAE) reactive to aa 17-24 Aβ and to APP -