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Antibodies

22 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
Ion Channels From manufacturers (22)
Sigma Aldrich polyclonal
Rabbit
(affinity isolated, PBS, BSA, sucrose, azide, lyophilized)
IB, IH, IP Various species, Rat immunogen = synthetic peptide corresponding to aa 1491-1508 of the α subunit of rat type I voltage-gated sodium channel, with additional C-terminal cysteine. (epitope corresp. to the sequence in the intracellular loop between the III and IV domains of the VGSC α subunit) recognizes the α subunit of VGSC -
Sigma Aldrich polyclonal
Rabbit
(affinity isolated, PBS, BSA, azide, lyophilized)
IB Rat immunogen = synthetic peptidecorresp. to aa 197-215 of the β2 subunit of rat voltage-gated sodium channel recognizes the β2 subunit of VGSC -
Sigma Aldrich polyclonal
Rabbit
(affinity isolated, PBS, BSA, azide, lyophilized)
IB, IH, IP Mouse, Rat immunogen = synthetic peptide corresp. to aa 465-481 of the α subunit of rat type I voltage-gated sodium channel.(epitope corresp. to sequence in the intracellular loop between the I and II domains of type I VGSC α subunit) recognizes the type I VGSC α subunit -
Alomone polyclonal
Rabbit
(affinity purified, BSA, PBS, sucrose, azide, lyophilized)
IH, WB Rat epitope = peptide EAGDD ERELA LQRLG PHEG(C), corresp. to residues 177-195 of rat Kv3.4 Recognizes Kv3.4, intracellular region, N-terminal -
Alomone polyclonal
Rabbit
(affinity purified, BSA, PBS, azide, lyophilized)
WB Rat epitope = peptide KSPITPGSR GRYSRDRAC corresp. toresidues 701-718 of rat Kv3.3 Recognizes only splice variant Kv3.3 –1, intracellular region, C-Terminus -
Alomone polyclonal
Rabbit
(affinity purified, BSA, PBS, azide, lyophilized)
IH, WB Rat epitope = peptide (C)RSRKVD KRSDPYH, corresp. to amino acid residues 81-93 of human KCNE3 Recognizes KCNE3; directed against the intracellular C-terminal part of the protein -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(affinity purified, BSA, PBS, sucrose, azide, lyophilized)
IH, WB Mouse, Rat immunogen = purified peptide from 465-481 of alpha subunit of rat type I voltage-gated sodium channel (VGSC) Recognizes type I alpha subunit of VGSC. Does not cross react with any other sodium channel antigens tested so far -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(affinity purified, BSA, PBS, azide, lyophilized)
IH, WB Mouse, Rat immunogen = purified peptide of alpha subunit (aa 467-485) of rat type II voltage-gated sodium channel (VGSC) Recognizes type II alpha subunit of VGSC. Does not cross react with any other sodium channel antigens tested so far -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(affinity purified, glycine/Tris, azide, lyophilized)
WB Human immunogen = highly purified peptide from human Nav1.2 Nav1.2 (SCN2A); 228 kDa protein band in WB -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(affinity purified, PBS, BSA, sucrose, azide, lyophilized)
IH, WB Rat immunogen = highly purified peptide corresp. to residues 197-215 of rat beta2 subunit of voltage-gated Na+ channels Recognizes Nab2. The epitope specific for Nab2 is not present in any other known proteins -
Calbiochem EMD Biosciences polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide)
IB Human, Rat immunogen = synthetic peptide corresponding to amino acids 185-197 of human VDAC detects ~31 kDa (VDAC) porin protein -
Cell Signaling polyclonal
Rabbit
(liquid, HEPES, NaCl, BSA, glycerol, protein A/affinity purified)
IH, WB Bovine, Human, Mouse, Rat immunogen = synthetic peptide corresp. to the N-terminus of human VDAC-1 (KLH-coupled) detects endogenous levels of total VDAC protein -
Abcam monoclonal
IgG2a
Mouse
(liquid, Tris, Na acetate, NaCl, BSA, azide, protein A purified)
ELISA, IC, WB Human immunogen = full length purified native human protein specific for the N-terminal region of human porin -
Abcam polyclonal
IgG
Rabbit
(liquid, KPBS, azide, affinity purified)
ELISA, IF, WB Human, Rat immunogen = synthetic peptide: N D G T E F G G S I Y Q K, corresp. to aa185-197 of human VDAC/Porin cross reactivity will occur with all forms of VDACs including VDAC1, VDAC2 (4 isoforms) and VDAC3(2 isoforms) -
Abcam monoclonal
IgG2b
Mouse
(liquid, NaOAc, NaCl, Tris-HCl, azide)
IC, WB Human immunogen = recombinant fragment (human) (N-terminal). Porin 31HL from EBV-transformed human B-lymphocytes VDAC/Porin - Mitochondrial Marker -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
IC, IF, IH, WB Dog, Chicken, Human, Mouse, Rat, Chinese hamster immunogen = Synthetic peptide derived from residues 150 - 250 of human VDAC1 / Porin; seq. is completely conserved between isoforms 1, 2 and 3 detects all 3 isoforms of VDAC -
Novus Biologicals polyclonal
Rabbit
(affinity purified antisera, TBS, saline, azide)
WB Cow, Human, Mouse immunogen = synthetic peptide within the N-terminal region [residues 1-100] of the human TREK 1 protein detects TREK1 (note: it is essential to run against membrane preps) -
Novus Biologicals polyclonal
Rabbit
(antisera, Hepes, BSA, glycerol)
IH, WB Rodent (various), Xenopus immunogen = peptide from the C-terminus of the Kv2.2 subunit region of Xenopus and rodent, conj. to KLH Specific for the ~125k Kv 2.2 subunit of the Voltage Gated Potassium Channel protein -
AnaSpec polyclonal
Rabbit
(liquid, affinity purified, BSA, PBS, azide)
IH Human, Mouse, Rat immunogen = a synthetic peptide corresponding to the amino acids 184-204 of rat potassium channel Kv3.2 recognizes potassiuim chanel Kv3.2 -
AnaSpec polyclonal
Rabbit
(liquid, affinity purified, BSA, PBS, azide)
WB Human, Rat immunogen = a synthetic peptide corresponding to the C-terminus of human potassium channel Kv4.3 recognizes potassiuim chanel Kv4.3 -
AnaSpec polyclonal
Rabbit
(liquid, affinity purified, PBS, BSA, azide)
IH, WB Human, Mouse, Rat immunogen = a synthetic peptide derived from the amino acids 1491-1508 of α subunit of rat type I voltage-gated sodium channel detects type I sodium channel -
Abcam monoclonal
IgG2a
Mouse
(liquid, PBS, no preservative, protein A purified)
ELISA, WB Human immunogen = recombinant fragment corresp. to aa1-100 of human VDAC1 / Porin VDAC/porin -