The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

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	Name	Source	Clonality & Isotype	Host & Formulation	Method	Reactivity	Immunogen/ Epitope	Specificity	Availability
p53 From manufacturers (87)
	p53	LifeSpan Biosciences, Inc.	polyclonal	Rabbit (protein A/G purified)	-	Mouse, Rat	immunogen = synthetic peptide	p53	-
	p53	LifeSpan Biosciences, Inc.	polyclonal	Rabbit (protein A/G purified)	-	Human	immunogen = synthetic peptide	p53	-
	p53	LifeSpan Biosciences, Inc.	polyclonal	Rabbit	-	Human	-	p53	-
	p53	LifeSpan Biosciences, Inc.	polyclonal	Rabbit	-	Human	-	p53	-
	p53	LifeSpan Biosciences, Inc.	polyclonal	Rabbit	-	Human	-	p53	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein A purified)	-	Human	immunogen = P53 β-galactosidase fusion protein	p53 mutant and wildtype forms	-
	p53 phos Ser33	LifeSpan Biosciences, Inc.	polyclonal	Rabbit (protein A purified)	-	Human	immunogen = synthetic phosphopeptide corresp. to residues surrounding Ser33 of human p53 (KLH coupled)	endogenous levels of p53 only when phosphorylated at serine 33	-
	p53	LifeSpan Biosciences, Inc.	polyclonal	Rabbit (unpurified serum)	-	Human	immunogen = synthetic peptide corresp. to aa367-379 of human p53 (S H L K S K [AcK] G Q S T S R, where AcK denotes acetyllysine) (KLH coupled)	specific for p53 acetylated in vitro by recombinant p300, and for peptide containing acetyllysine 373 but not for the peptide containing acetyllysine 320; modest crossreactivity for p53 acetylated in vitro by recombinant PCAF	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein A purified, conj. FITC)	-	Human	immunogen = human p53	p53	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (IgG fractionation)	-	Primate (various), Human	immunogen = human recombinant wild-type p53 oncoprotein	p53	-
	p53 phos Ser392	LifeSpan Biosciences, Inc.	monoclonal	Mouse (DEAE-column chromatography)	-	Human, Mouse	immunogen = peptide surrounding the human p53, phosphorylated at Ser392 and coupled to KLH	recognizes only p53 phosphorylated at Ser392 residue; no reaction with non-phosphorylated p53 or unrelated phospho-proteins	-
	p53	LifeSpan Biosciences, Inc.	polyclonal	Rabbit (unpurified serum)	-	Human, Mouse, Rat	immunogen = peptide surrounding the human p53, acetylated at Lys373, coupled to KLH	recognizes only p53 acetylated at K373 residue; no reaction with non-acetylated p53 or unrelated proteins	-
	p53	LifeSpan Biosciences, Inc.	polyclonal	Rabbit (unpurified serum)	-	Human, Mouse, Rat	immunogen = synthetic peptide surrounding the human p53, acetylated at Lys320, KLH coupled. Lys320 was acetylated by PCAF	recognizes only p53 acetylated at K373 residue; no reaction with non-acetylated p53 or unrelated proteins; no crossreaction with p63 or p73	-
	p53 phos Ser392	LifeSpan Biosciences, Inc.	monoclonal	Mouse	-	Human	immunogen = synthetic peptide corresp. to a portion of p53 phosphorylated at Ser392	p53 when phosphorylated at Ser392	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein A purified)	-	Human	immunogen = recombinant human wild-type p53 protein	p53	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse	-	Human	immunogen = recombinant human wild-type p53 protein	reacts with a denaturation-resistant epitope of p53	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein G purified)	-	Human	immunogen = human p53 β-galactosidase protein	p53 mutant and wild-type forms; epitope maps within the N-terminus (aa32-79)	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein A purified)	-	Human, Monkey, Hamster, Mouse, Rat	immunogen = p53 protein C-terminal aa370-378	recognizes a conserved, denaturation-resistant determinant of the p53 protein; epitope maps within the C-terminus (aa370-378)	-
	p53 (3H2821)	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein A purified)	-	Human	immunogen = SV40 - transformed cell line BALB/c SVA31E7	p53 wildtype; epitope between aa 88-109	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein A purified)	-	Chicken, Cow, Human, Monkey, Hamster, Mouse, Rat	immunogen = P53 β-galactosidase fusion protein	p53 mutant; epitope between aa 156-214	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein A purified; conj. FITC)	-	Bovine, Human, Monkey	immunogen = recombinant human wild type p53 protein expressed in E. coli	p53 mutant and wildtype; epitope maps within N-terminus aa 37-45	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein G purified)	-	Hamster, Mouse, Rat	immunogen = SV40 transformed cell line BALB/c SVA31 E7	p53 wildtype not mutant; epitope maps between aa 88-93	-
	p53 binding protein 1	LifeSpan Biosciences, Inc.	monoclonal	Mouse (ascites)	-	Human, Mouse	immunogen = mix of three GST fusion proteins corresp. to residues 1-337, 338-671, and 1331-1664 of human 53BP1	p53BP1 (~250kD)	-
	p53 binding protein1	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein G purified)	-	Human	immunogen = mix of three GST fusion proteins corresp. to residues 1-337, 338-671, and 1331-1664 of human 53BP1	p53 BP1 (~250kD)	-
	p53 phos Ser392	LifeSpan Biosciences, Inc.	polyclonal	Rabbit (protein G purified)	-	Human, Mouse	immunogen = synthetic phosphopeptide corresp. to residues surrounding Ser392 of human p53 (KLH coupled)	p53, when phosphorylated at serine 392	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (IgG fractionation)	-	Hamster	-	p53	-
	p53	LifeSpan Biosciences, Inc.	polyclonal	Rabbit	-	Human	-	p53	-
	p53	LifeSpan Biosciences, Inc.	polyclonal	Rabbit	-	Human	-	p53	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (DEAE-column chromatography)	-	Human	immunogen = p53 β-galactosidase fusion protein	p53; epitope located in the N-terminus of p53	-
	p53 phos Ser392	LifeSpan Biosciences, Inc.	polyclonal	Rabbit	-	Human	immunogen = synthetic phosphopeptide corresp. to the regions surrounding the phosphorylated Ser392 residue	p53 when phosphorylated at Ser39	-
	p53 (3H2821)	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein A purified; conj. FITC)	-	Human	-	p53 wildtype; epitope between aa 88-109	-
	p53	LifeSpan Biosciences, Inc.	polyclonal	Rabbit (unpurified serum)	-	Human	immunogen = recombinant human p53	p53	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein A purified)	-	Human	immunogen = human p53	p53 wild-type and mutant forms	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein A purified)	-	Human, Mouse	immunogen = human p53	p53 wild-type and mutant forms under denaturing conditions; reacts with mutant form under non-denaturing conditions but not wild-type under these conditions	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (supernatant)	-	Human	immunogen = human p53 β-galactosidase fusion protein	p53 wild-type and mutant forms	-
	p53	LifeSpan Biosciences, Inc.	monoclonal	Mouse (protein A purified; conj. to FITC)	-	Human	immunogen = murine p53 wild type oncogene	p53 wild-type only	-
	p53	LifeSpan Biosciences, Inc.	polyclonal	Rabbit	-	Human	immunogen = synthetic peptide corresp. to a portion of human p53	p53	-
	p53 (BP53-12)	Chemicon and Upstate are Millipore	monoclonal IgG2a	Mouse (liquid, PBS, BSA, azide, purified)	-	Human	immunogen = recombinant human wild type p53	detects p53	-
	p53, C-terminus (PAb1802)	Chemicon and Upstate are Millipore	monoclonal IgG1	Mouse (liquid, supernatant, azide)	-	Human	immunogen = human p53 beta galactosidase fusion protein (wild & mutant, a.a. 306-393, C-terminus)	detects p53, wild and mutant, C-terminus	-
	p53, C-terminus (PAb122)	Chemicon and Upstate are Millipore	monoclonal IgG2b	Mouse (liquid, BSA, PBS, azide, FITC conj.)	-	Human, Monkey, Hamster, Mouse, Rat	(a.a. 370-378, C-terminus)	reacts with a conserved, denaturation resistant determinant of the p53 protein	-
	p53	Chemicon and Upstate are Millipore	polyclonal	Rabbit (liquid, serum, azide)	-	Human	immunogen = recombinant p53 protein (wild & mutant)	detects p53 (wild and mutant forms) under denaturing and non denaturing conditions	-
	p53 phos Ser392	Chemicon and Upstate are Millipore	polyclonal	Rabbit (liquid, Hepes, saline, BSA, glycerol, affinity purified)	-	Human	immunogen = synthetic phospho peptide corresp. to a.a. residues surrounding the Ser392 of p53	detects 53 kDa p53 protein phosphor. at Serine 392	-
	p53 (DO-7)	Chemicon and Upstate are Millipore	monoclonal IgG2b	Mouse (liquid, PBS, Tween, ProClin, purified, ready-to-use when used with IHC Select™ detection kit and protocol)	-	Human	immunogen = human p53 (prediluted,wild & mutant, a.a. 19-26)	detects human p53, wild and mutant forms	-
	p53, wild and mutant (BP53-12)	Chemicon and Upstate are Millipore	monoclonal IgG2a	Mouse (liquid, BSA, PBS, azide, purified)	-	Human	(a.a. 20-25, wild and mutant)	reacts with the 53 kDa nuclear protein	-
	p53 (BP53-12)	BioLegend	monoclonal IgG2a,κ	Mouse (affinity purified, TBS, azide)	-	Primate (various), Human	immunogen = amino acid: 20-25 of human p53	recognizes human and non-human primate p53	-
	p53 acetyl Lys305	None	polyclonal IgG	Rabbit (affinity purified, PBS, azide, glycerol)	-	Human	immunogen = modified peptide, PPGSTK*RALPN (p53 residues 300-310)	recognizes acetylated human p53 (Lys305)	discontinued
	p53 acetyl Lys382	None	polyclonal IgG	Rabbit (affinity purified, PBS, azide, glycerol)	-	Human	immunogen = modified peptide, STSRHKK*LMFKT (p53 residues 376-387)	recognizes acetylated human p53 (Lys382)	discontinued
	p53 phos Ser392 (FP3.2)	None	monoclonal IgG1,κ	Mouse (affinity purified, PBS, azide)	-	Human	immunogen = modified peptide, (RHKKLMFK TEGPDS*D) corresponding to amino acids 378-393 of human p53	recognizes human phosphorylated p53 (Ser392)	discontinued
	p53 (B-P3)	Biosource Invitrogen	monoclonal IgG2a	Mouse (purified IgG, PBS, preservative and endotoxin free, unconj.)	-	Primate (various), Human	immunogen = purified recombinant human p53(epitope within residues 18-30 of human p53)	p53; not observed to react with normal fibroblasts, nocross-reactivity with other proteins has been detected	-
	p53 Acetyl Lys382	Cell Signaling	polyclonal	Rabbit (HEPES, saline, glycerol, BSA, affinity purified)	-	Human	immunogen = synthetic acetylated peptide(KLH-coupled) corresponding to residues surroundingLys382 of human p53	detects endogenous levels of p53 only when acetylated atlysine 382; does not cross-react with otheracetylated proteins	-
	p53 Acetyl Lys379	Cell Signaling	polyclonal	Rabbit (HEPES, saline, glycerol, BSA, affinity purified)	-	Human, Monkey	immunogen = synthetic acetylated peptide(KLH-coupled) corresponding to residues surroundingLys379 of mouse p53	detects endogenous levels of p53 only when acetylated at Lys379 (mouse protein) or Lys382 (human protein)	-
	p53 (1C12)	Cell Signaling	monoclonal IgG1	Mouse (HEPES, saline, glycerol, BSA, azide)	-	Human, Monkey, Mouse, Rat	immunogen = synthetic peptide (KLH coupled)corresp. to residues surrounding Ser20 ofhuman p53	reacts with endogenous levels of total p53 protein	-
	p53 (7F5)	Cell Signaling	monoclonal IgG	Rabbit (HEPES, saline, glycerol, BSA)	-	Human, Monkey	immunogen = an MBP-p53 fusion protein	reacts with endogenous levels of total p53 protein	-
	p53	Cell Signaling	polyclonal	Rabbit (HEPES, saline, glycerol, BSA, affinity purified)	-	Human, Monkey, Rat	immunogen = an MBP-p53 fusion protein	reacts with endogenous levels of total p53 protein; does not cross-react with other p53-related proteins	-
	p53 phos Ser23	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Mouse	immunogen = a synthetic phosphopeptide (ETF-pS-GLW) corresponding to mouse p53 at the phosphorylated site of Serine 23	detects p53 phosphor. at Serine 23	-
	p53 paired18	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Monkey, Mouse	immunogen = a synthetic peptide (LPLSQET) corresponding to amino acids surrounding Serine 18 of mouse p53	detects p53	-
	p53, CT	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human, Mouse, Rat	immunogen = a synthetic peptide (KKGQSTS) corresponding to human p53 surrounding C-terminal amino acids	detects p53	-
	p53, paired20	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human, Monkey	immunogen = a synthetic peptide (ETFSDLW) corresponding to amino acids surrounding Serine 20 of human p53	detects p53	-
	p53, paired37	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human, Monkey	immunogen = a synthetic peptide (PLPSQAM) corresponding to amino acid surrounding Serine 37 of human p53	detects p53	-
	p53, paired392	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human, Monkey	immunogen = a synthetic peptide (EGPDSD) corresponding to amino acid surrounding Serine 392 of human p53	detects p53	-
	p53, paired46	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human, Monkey	immunogen = a synthetic peptide corresponding to amino acids surrounding Serine 46 of human p53	detects p53	-
	p53, phos Ser20	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (ETFpSDLW) corresponding to human p53 at the phosphorylated site of Serine 20	detects p53 phosphor. at Serine 20	-
	p53, phos Ser37	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (PLPpSQAM) corresponding to human p53 at the phosphorylated site of Serine 20	detects p53 phosphor. at Serine 37	-
	p53, phos Ser392	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (EGPDpSD) corresponding to human p53 at the phosphorylated site of Serine 392	detects p53 phosphor. at Serine 392	-
	p53, phos Ser46	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (LMLpSPDD) corresponding to human p53 at the phosphorylated site of Serine 46	detects p53 phosphor. at Serine 46	-
	p53, phos Ser15	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (PPLpSQET) corresponding to human p53 at the phosphorylated site of Serine 15	detects p53 phosphor. at Serine 15	-
	p53, phos Ser9	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (SDPpSVEP) corresponding to human p53 at the phosphorylated site of Serine 9	detects p53 phosphor. at Serine 9	-
	p53, phos Ser20	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (ETFpSDLW) corresponding to human p53 at the phosphorylated site of Serine 20	detects p53 phosphor. at Serine 20	-
	p53, phos Ser37	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (PLPpSQAM) corresponding to human p53 atthe phosphorylated site of Serine 37	detects p53 phosphor. at Serine 37	-
	p53, phos Ser392	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (EGPDpSD) corresponding to human p53 at the phosphorylated site of Serine 392	detects p53 phosphor. at Serine 392	-
	p53, phos Ser46	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (LMLpSPDD) corresponding to human p53 at the phosphorylated site of Serine 46	detects p53 phosphor. at Serine 46	-
	p53, phos Ser6	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (MEEPQpSDPSVEP-NH2) corresponding to human p53 at the phosphorylated site of Serine 6	detects p53 phosphor. at Serine 6	-
	p53, paired 6	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (MEEPQSDPSVEP) corresponding to N-terminus of human p53	detects p53	-
	p53, phos Ser9	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (SDPpSVEP) corresponding to human p53 at the phosphorylated site of Serine 9	detects p53 phosphoryl. at Serine 9	-
	p53, phos Ser15	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (PPLpSQET) corresponding to human p53 at the phosphorylated site of Serine 15	detects p53 phosphoryl. at Serine 15	-
	p53, paired 9	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (MEEPQSDPSVEP) corresponding to N-terminus of human p53	detects p53	-
	p53, paired 15	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Human	immunogen = a synthetic peptide (MEEPQSDPSVEP) corresponding to N-terminus of human p53	detects p53	-
	p53, phos Ser18/23	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Mouse	immunogen = a synthetic phosphopeptide (L-pS-QETF-pS-GL) corresponding to mouse p53 at the phosphorylated site of Serine 18 and 23	detects p53 phos at Serine 18 and 23	-
	p53, paired 23	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Monkey, Mouse	immunogen = a synthetic peptide (ETFSGLW) corresponding to amino acids surrounding Serine 23 of mouse p53	detects p53	-
	p53, paired 18/23	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Monkey, Mouse	immunogen = a synthetic peptide (LSQETFSG) corresponding to amino acids surrounding Serine 18 and 23 of mouse p53	detects p53	-
	p53 phos Ser18	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, PBS, azide)	-	Mouse	immunogen = a synthetic phosphopeptide (LPL-pS-QET) corresponding to mouse p53 at the phosphorylated site of Serine 18	detects p53 phosphor. at Serine 18	-
	p53 CT	Anaspec	polyclonal IgG	Rabbit (liquid, affinity purified, MOPS, BSA, glycerol)	-	Zebra fish	immunogen = a synthetic peptide derived from the zebrafish p53 surrounding the C-terminal region (CT)	detects p53	-
	p53	Novocastra	polyclonal	Rabbit (serum, PBS, BSA, azide, lyophilized)	-	Mouse	immunogen =recomb. mouse p53 protein	p53, nuclear	-
	p53 (DO-7)	DAKO	monoclonal IgG2b,κ	Mouse (liquid, cell culture supernatant, Tris/HCl, azide)	-	Human	immunogen = recombinant human wild type p53 protein expressed in E. coli (epitope between amino acids 37 and 45)	reacts with the wild type and mutant type of the p53 protein; a 53 kDa band in WB	-
	p53 (318-6-11)	DAKO	monoclonal IgG2b,κ	Rabbit (liquid, cell culture supernatant, stabilizing protein, Tris/HCl, azide)	-	Human	immunogen = synthetic peptide from the region of human p53 containing amino acids 49-68	for the identificationof p53 in normal and neoplastic tissue, staining is nuclear; labels a major band at 53 kD in WB	-
	p53 (DO-7)	DAKO	monoclonal IgG2b,κ	Mouse (liquid, buffer, stabilizing protein, azide; ready-to-use with AutostainerLink instruments)	-	Human	immunogen = recombinant human wild type p53 protein (epitope near N terminus, within aa 37-45)	labels both wild type and mutant type of the p53 protein; labels a 53 kDa band in WB	-
	p53 (DO-7)	DAKO	monoclonal IgG2b,κ	Mouse (liquid, buffer, stabilizing protein, azide; ready-to-use with Dako Autostainer /Autostainer Plus instruments)	-	Human	immunogen = recombinant human wild type p53 protein (epitope near N terminus, within aa 37-45)	labels both wild type and mutant type of the p53 protein, nuclear staining; labels a 53 kDa band in WB	-