The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

619 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
Amyloid-β From labs (7)
mAb27(Lars Nilsson, Department of Public Health and Caring Sciences/Molecular Geriatrics, Uppsala University, Uppsala, SwedenPaper, Anna Lord.Reference: Lord, 2009 monoclonal
Mouse
- Human, Mouse epitope in themid-domain of the Arctic Aβ peptide amyloid-beta -
mAb158(Hillevi Englund, Department of Public Health/Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden)References: Lord, 2009Englund, 2007.Recently, Anna Lord reported that the mAb158 sandwich ELISA detects synthetic protofibrils, as well as protofibrils in biological samples from a variety of mouse models monoclonal
IgG2a
Unknown Host
(supernatant, protein-G purified)
- Human immunogen = 30 μg Aβ1–42 Arc protofibrils beta amyloid protofibrils; does not bind to other amyloids or to amyloid precursor protein (APP). The conformation selectivity of mAb158 is exclusive for amyloid-β (Aβ) as itdid not display any binding to other amyloid fibrils; mAb158 did not immuno precipitate α-APPs from cell media or full-length APP from mouse brain homogenate; binds to Aβ fibrils in addition to oligomeric Aβ; has some cross-reactivity with monomeric Aβ -
mAb1C3(Hillevi Englund, Department of Public Health/Molecular Geriatrics, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden)References: Lord, 2009Englund, 2007 monoclonal
IgG1
Unknown Host
(supernatant, protein-G purified)
- Human immunogen = 30 μg Aβ1–42 Arc protofibrils affinity for Aβ protofibrils, Aβ Arc protofibrils, LMW-Aβ, and Aβ1–16; mAb1C3 did not show any conformation selectivity -
Seubert, Elan Pharmaceuticals monoclonal
Mouse
- Human, Mouse immunogen = synthetic peptide, central domain 13-28 of Aβ1-42 (epitope at 16-23) - -
amyloid-beta 40(Johnson -Wood,Athena Neurosciences Co, San Francisco, CApapers:Citron, et al. PNAS, Nov. 12, 1996, and Johnson-Wood, et al. PNAS, Feb. 18, l997)References:Okereke, 2009Li, 2009Serneels, 2009Brody, 2008Shankar, 2008DeMatos, 2001,Buttini, 2002 monoclonal
Mouse
- - immunogen = the peptide NH2-CYS-NH-CH2-(CH2)5-CO-GLMVGGVV-COOH coupled to sheep anti-mouse IgG amyloid-beta 40 (recognizes amino acids 33-40);no cross-reactivity with Aβ1–42 -
12H7(Johnson -Wood,Athena Neurosciences Co, San Francisco, CApaper:Johnson-Wood, et al. PNAS, Feb. 18, l997) monoclonal
Mouse
- - immunogen = the peptide sequence aa. 33-42 of beta amyloid, coupled to sheep anti-mouse IgG reacts with amyloid-beta 42 (recognizes amino acids 33-42);no cross-reactivity with Aβ1–40 -
m266(R. B. DeMattos, Washington University School of Medicine, St. Louis, MOpaper:DeMattos, et al., PNAS July 17, 2001)References:Kim, 2009Okereke, 2009Yan, 2009 Serneels, 2009Brody, 2008 monoclonal
Mouse
(see Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, IN)
- Mouse immunogen = central domain of Aβ, residues 13–28 amyloid beta -
Amyloid-β From manufacturers (93)
BioLegend polyclonal
Rabbit
(liquid, PBS, IgG fraction, no preservative or carrier protein)
- Rodent (various) immunogen = rodent amyloid-β peptide rodent Amyloid-β ,all isoforms Available from BioLegend
BioLegend polyclonal
Rabbit
(liquid, PBS, glycerol, no carrier protein or preservative, boitin labeled)
- Rodent (various) - all isoforms of rhodent Aβ Available from BioLegend
BioLegend monoclonal
IgG2b
Mouse
(liquid, PBS, no preservatives or carrier proteins, HRP conj.)
- Human, Mouse epitope lies within amino acids 18-22 of the beta amyloid peptide (VFFAE) reactive to aa 17-24 Aβ and to APPs Available from BioLegend
BioLegend polyclonal
Rabbit
(liquid, PBS, no carrier protein or preservative, affinity purified)
- - imunogen = using beta amyloid peptide (amino acids 1-16) conjugated to KLH reacts with all isoforms of beta amyloid Available from BioLegend
None monoclonal
IgG1
Mouse
(liquid, purified F(ab')2 frag of clone 6E10 monoclonal ab, PBS, no preservatives or carrier proteins)
- Human epitope = lies within aa 3-8 of β-amyloid peptide (EFRHDS) reactive to aa 1-16 of β-amyloid peptide (precursor forms and abnormally processed isoforms) Discontinued
BioLegend monoclonal
IgG1
Mouse
(crude ascites)
- Human the epitope lies within amino acids 3-8 of beta amyloid (EFRHDS) reactive to aa 1-16 of Aβ and to APP; reacts to the abnormally processed isoforms, as well as precursor forms Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative or carrier proteins, protein A purified, biotinylated)
- Human, Mouse - reactive to C-terminus of Amyloid β and specific for the isoform ending at the 40th amino acid -
None polyclonal
IgG
Rabbit
(Purified IgG fraction, PBS; no preservatives or carrier proteins)
- Human immunogen = aa residue 32-40 of Amyloid-β 1-40 peptide, conj. to KLH specific for the C-terminus of Aβ 40; reacts extremely well with the 40 isoform; no cross reaction with Aβ 42 or with APP Discontinued
None polyclonal
Rabbit
(liquid, PBS, glycerol, no preservative or carrier proteins, IgG frac., biotinylated)
- Human immunogen = amyloid-β peptide conj. to KLH specific for C-terminus of Aβ 40 isoforms; no cross-reaction with Aβ 42 or APP Discontinued
None polyclonal
Rabbit
(liquid, PBS, no preservative or carrier proteins, affinity purified)
- Human immunogen = amyloid-β conj. to KLH specific for C-terminus of Aβ 40 isoform; no cross-reaction with Aβ42 or APP Discontinued
None polyclonal
Rabbit
(liquid, PBS, glycerol, no preservative or carrier proteins, affinity purified, bintinylated)
- Human, Mouse immunogen = amyloid-β conj. to KLH specific for C-terminus of Aβ40 isoform; no cross-reaction with Aβ42 or APP Discontinued
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, biotin labelled)
- Human, Mouse - reactive to C-terminus of Amyloid β and specific for the isoform ending at the 42nd amino acid Available from BioLegend
None polyclonal
IgG
Rabbit
(purified, IgG fraction, PBS, no preservatives or carrier proteins)
- Human, Mouse immunogen = amyloid β 1-42 peptide, conj. to KLH specific for the C-terminus of Aβ 1-42; no cross reaction with Aβ 1-40 or APP Discontinued
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS no preservative or carrier proteins, IgG frac., protein A purified)
- Human, Mouse - reactive to C-terminus of Amyloid β and specific for the isoform ending at the 43rd amino acid Available from BioLegend
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 40 Antibody 4G8, protocol)
- Human, Mouse, Rat - recognizes human beta Amyloid 40 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 38 Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 38 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 38 Antibody 6E10, protocol)
- Human epitope lies within amino acids 4-9 of the beta Amyloid peptide (FRHDSG) recognizes human beta Amyloid 38 peptide in human cerebrospinalfluid (CSF) -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 40 Antibody 4G8, protocol)
- Human, Mouse, Rat - recognizes human beta Amyloid 40 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 40 Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 40 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 40 Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 40 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 40 Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 40 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 40 Antibody 4G8, protocol)
- Human, Mouse, Rat - recognizes human beta Amyloid 40 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 40 Antibody 4G8, protocol)
- Human, Mouse, Rat - recognizes human beta Amyloid 40 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 40 Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 40 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 40 Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 40 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 40 Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 40 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ Antibody 4G8, protocol)
- Human, Mouse, Rat - recognizes human beta Amyloid38, 40, 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid38, 40, 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ Antibody 4G8, protocol)
- Human, Mouse, Rat - recognizes human beta Amyloid 38, 40, 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 38, 40, 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ Antibody 4G8, protocol)
- Human, Mouse, Rat - recognizes human beta Amyloid38, 40, 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ Antibody 4G8, protocol)
- Human, Mouse, Rat - recognizes human beta Amyloid 38, 40, 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid38, 40, 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 38, 40, 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 40 Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 40 peptide in cerebral spinal fluid samples -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 40 Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 40 peptide in cerebral spinal fluid samples -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 42 Antibody 6E10, protocol)
- Human - recognizes beta Amyloid 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 42 Antibody 6E10, protocol)
- Human, Mouse, Rat - recognizes beta Amyloid 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 42 Antibody 6E10, protocol)
- Human - recognizes beta Amyloid 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 42 Antibody 6E10, protocol)
- Human - recognizes beta Amyloid 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 42 Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 42 Antibody 6E10, protocol)
- Human - recognizes human beta Amyloid 42 peptide -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 42 Antibody 6E10, protocol)
- Human - recognizes beta Amyloid 42 peptide in cerebral spinal fluid samples -
Meso Scale Discovery kit
Mouse
(96 well ELISA, SULFO-TAG™ Anti Aβ 42 Antibody 6E10, protocol)
- Human - recognizes beta Amyloid 42 peptide in cerebral spinal fluid samples -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, antisera, azide)
- Human Immunogen = synthetic peptide corresp. to aa seq. 1-14 of human Amyloid Beta protein recognizes β-Amyloid (87kDa) -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, Tris-glycine saline, Thimerosal, affinity purified)
- Human Immunogen = recombinant protein fragment contain a sequence corresp. to a region within aa602 and 757 of human APP recognizes β-Amyloid (87kDa) -
OYC monoclonal
IgG2b
Rabbit
(liquid, PBS, azide, agarose affinity purified)
- Human immunogen = synthetic peptide of human βAP 1-40 The antibody reacts with βAP1-40 and secretory amyloid protein precursor (sAPP), but not with βAP17-42 -
OYC polyclonal
Rabbit
(liquid, antiserum, azide)
- Human immunogen = synthetic peptide of human β-Amyloid 17-42 The antibody reacts with βAP1-40 and βAP17-42, but not with secretory amyloid protein precursor (sAPP) -
OYC polyclonal
Rabbit
(liquid, antiserum, azide)
- Human immunogen = synthetic peptide of human β-Amyloid 1-40 The antibody reacts with βAP1-40, but not with either βAP17-42 or secretory amyloid protein precursor (sAPP) -
Novus Biologicals polyclonal
IgG
Rabbit
(lyophilized, no preservative, affinity purified)
- - immunogen = synthetic peptide containing aa1-40 of amyloid recognizes β-Amyloid (1-40) -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, whole antisera, azide)
- Human, Mouse immunogen = synthetic peptide corresponding to amino acid residues G L M V G G V V reacts with Aβ 40; no cross reactivity with Aβ 42 -
Novus Biologicals polyclonal
IgG
Rabbit
(lyophilized, no preservative, affinity purified)
- - immunogen = synthetic peptide containing C-terminal domain of Amyloid beta (37-42). recognizes β-Amyloid 42 -
BD Pharmingen polyclonal
Rabbit
(liquid, buffered sol, azide, affinity purified)
- Human immunogen = synthetic peptide [1-40], D A E F R H D S G Y E V H H Q K L V F F A E D V G S N K G A I I G L M V G G V V Amyloid Beta [1-40]; not [1-42] or [1-43] -
BD Pharmingen polyclonal
Rabbit
(affinity purified)
- Human synthetic peptide [1-42] Amyloid Beta [1-42]; not [1-40] or [1-43] -
Pierce Thermo Scientific monoclonal
IgG2aκ
Mouse
(liquid, Biotin)
- Human immunogen = synthetic peptide corresponding to 28 a.a. sequence all forms of β-Amyloid -
Santa Cruz monoclonal
IgG2a
Mouse
(liquid, PBS, azide, PEG, sucrose)
- Human immunogen = C-terminal of human β-amyloid detects synthetic β-Amyloid [the C-termini of Aβ (1-43); no cross-reaction with β- amyloid (1-40 or 1-42) -
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, gelatin, azide)
- Human immunogen = synthetic peptide corresp. to aa 1-17 of human β-amyloid β-Amyloid -
Santa Cruz monoclonal
IgG2a
Mouse
(liquid, PBS, gelatin, azide)
- Human immunogen = synthetic peptide corresp. to aa 1-16 of human β-amyloid detects synthetic β-Amyloid [the N-termini of Aβ (40) and Aβ (42)]; no cross-reaction with recombinant β- amyloid (aa 601-744) -
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, gelatin, azide)
- Human immunogen = recombinant human β-amyloid695 β-Amyloid; epitope within the first 200 aa -
Santa Cruz monoclonal
IgG2a
Mouse
(liquid, PBS, gelatin, azide)
- Human, Mouse, Rat immunogen = aa 672-714 of amyloid A4 representing full length of human β-amyloid β-Amyloid, Amyloid A4 -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified)
- Human, Mouse, Rat immunogen = peptide mapping at the C-terminus of human β-amyloid β-amyloid, Amyloid A4 -
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, gelatin, azide)
- Human immunogen = aa 1-17 of human β-amyloid β-Amyloid -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, gelatin, azide)
- Human, Mouse, Rat immunogen = aa 672-714 of Amyloid A4 representing full-length of human β-amyloid protein β-Amyloid, Amyloid A4 -
Santa Cruz monoclonal
IgG2a
Mouse
(liquid, PBS, gelatin, azide)
- Human immunogen = beta-amyloid, synthetic peptide (epitope at amino terminus,aa 1-11) β-Amyloid -
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, gelatin, azide)
- Human immunogen = recombinant human β-amyloid695 β-Amyloid; epitope within the first 200aa -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, gelatin, azide)
- Human, Mouse, Rat immunogen = short aa containing phosphorylated Thr 668 of human β-amyloid β-Amyloid phos at Thr668 -
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, azide, PEG, sucrose)
- Human immunogen = N-terminal of human β-amyloid detection of extracellular β-Amyloid soluble peptide cleavage product of human origin; no cross-reaction with APP -
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, azide, PEG, sucrose)
- Human immunogen = C-terminal of human β-amyloid detection of the C-termini of β-Amyloid (1-40), also designated β-APP40, and β-Amyloid (1-42), also designated β-APP42, of human origin by IP; may cross-react with APP -
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, azide, PEG, sucrose)
- Human immunogen = N-terminal of human β-amyloid detection of extracellular β-Amyloid soluble peptide cleavage product of human origin; may cross-react with APP -
Santa Cruz monoclonal
IgG2a
Mouse
(liquid, PBS, gelatin, azide)
- Human immunogen = purified truncated recombinant human β-amyloid β-Amyloid -
Santa Cruz monoclonal
IgG2a
Mouse
(liquid, PBS, gelatin, azide)
- Human immunogen = synthetic peptide corresp. to aa 5-16 of human β-amyloid coupled to S3 and epinephrine β-Amyloid -
Santa Cruz monoclonal
IgG2a
Mouse
(liquid, PBS, azide, gelatin)
- Human immunogen = synthetic peptide corresp. to aa 5-16 of human β-amyloid detection of aa 5-16 of β-Amyloid -
Santa Cruz monoclonal
IgG2a
Mouse
(liquid, PBS, azide, gelatin)
- Human immunogen = synthetic peptide corresp. to aa 5-16 of human β-amyloid coupled to S3 and epinephrine detection of aa 5-16 of β-Amyloid -
Autogen Bioclear monoclonal
IgG1
Mouse
(liquid, PBS, gelatin, azide)
- Human immunogen = 28 aa synthetic peptide derived from human β-Amyloid β-Amyloid -
Santa Cruz monoclonal
IgG2b
Mouse
(liquid, PBS, gelatin, azide)
- Human immunogen = synthetic peptide corresp. to aa 1-40 of human β-amyloid β-Amyloid -
AbD Serotec polyclonal
IgG
Rabbit
(liquid, serum, azide)
- Human immunogen = highly purified antigen; aa seq. 1-14 of human amyloid beta protein. β-amyloid (87kDa) -
Sigma Aldrich monoclonal
IgG1
Mouse
(ascites, azide)
- Human immunogen = synthetic β-amyloid peptide (1-40) conjugated to KLH. (Epitope at aa 1-12) stains amyloid plaques within the cortex, and amyloid deposits in blood vessels of brain tissue -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(liquid, serum, azide)
- Human, Mouse immunogen = A synthetic β-amyloid peptide 1-40 conjugated to BSA.homologous to Aβ[1-28], Aβ[12-28] Aβ 1-40/42 -
Synaptic Systems
Cat# 218 203
polyclonal
Rabbit
(Lyophilized. Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.)
- Human, Mouse, Rat Synthetic peptide corresponding to amino acids 33-40 of Aβ40 coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue. Specific for Aβ40. No cross reactivity to Aβ38 or Aβ42. Confirmed available March 2014
Synaptic Systems
Cat# 218 003
polyclonal
Rabbit
(lyophilized. Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.)
- Human, Mouse, Rat Synthetic peptide pyr-EFRHD coupled to key-hole limpet hemocyanin via an added C-terminal cysteine residue. Specific for pyro-Glu Aβ (aka pE-Abeta, pGlu-Abeta, Abeta(3(pE)-40/42), pyro-glu-Abeta).WB: Detects purified Abeta pE3. Complex samples like brain extracts still have to be tested. Confirmed available March 2014
Vector Labs monoclonal
IgG1
Mouse
(lyophilized, supernatant, azide)
- Human immunogen = synthetic peptide representing residues8-17 on human beta amyloid molecule beta amyloid -
Zymed/ Invitrogen polyclonal
Rabbit
(liquid, PBS, azide, affinity purified)
- Human immunogen = a 30 aa synthetic peptide derived from the full-length amyloid-β peptide specific for the ~4-5 kDa Amyloid-β peptide (A-β), derived by cleavage from APP. -
Zymed/ Invitrogen monoclonal
IgG1κ
Mouse
(liquid, purified ascites, PBS, azide)
- Human immunogen = 28 aa synthetic peptide derived from β-Amyloid peptide β-Amyloid peptide (4-5kDa); high antibody concentration will react with A-α, B-α and γ subunits of fibrinogen -
Zymed/ Invitrogen monoclonal
IgG2aκ
Mouse
(liquid, PBS, azide, protein A purified)
- Human immunogen = synthetic peptide derived from the N-terminal region of human Amyoid-β specific for the N-terminal amyloid-β; recognizes mature (125 kDa) and immature (110 kDa) forms, and both the α- and β'-cleavage-derived N-terminal ectodomain of APP (sAPPα and sAPPβ) -
Calbiochem EMD Biosciences monoclonal
IgG2b
Mouse
(liquid, PBS)
- Human, Mouse immunogen = synthetic peptide corresp. to aa 17-24 of human β-amyloid peptide reactive to abnormally processed isoforms as well as precursor forms of β-amyloid peptide. -
Chemicon and Upstate are Millipore monoclonal
IgG2b
Mouse
(purified Ig, liquid, PBS, thimerosal)
- Dog, Human immunogen = amyloid-β, juxtamembrane EC domain, aa 17-24; epitope lies between aa 18-22 reactive to amyloid-β, aa 17-24 -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(liquid, PBS, azide, serum)
- Human immunogen = amyloid-β 20-40 conj. to KLH Amyloid-β 20-40 -
Sigma Aldrich monoclonal
IgG2b
Mouse
(ascites, purified, protein-A, PBS, sterile filtered)
- Human, Mouse immunogen = synthetic peptide corr. to aa 17-24 of β-amyloid, conj. to KLH; Epitope at aa 1-12 reactive to aa 17-24 of human amyloid β peptide; also recognizes the precursor forms and abnormally processed isoforms -
Chemicon and Upstate are Millipore monoclonal
IgG1
Mouse
(liquid, protein-G purified, buffer, Tris-glycine, azide)
- Human, Mouse immunogen = KLH-conjugated linear peptide corresponding to the C-terminus of Amyloid β42. reacts with human Amyloid β42 at the C-terminus -
Genetics Company, Inc. monoclonal
IgG2b
Mouse
(liquid, supernatant, stabilizer, no azide, affinity purified, conj. biotin)
- Dog, Human, Guinea Pig, Mouse, Rat, Cynomolgus C-terminal epitope mapping corresp. to aa residues 31-40 of human Aβ peptide recognizes Aβ-peptide, aa 31-40; selective for C-terminal of Aβ 1-40; not Aβ 1-38, Aβ 1-39, Aβ 1-42, Aβ 1-43 or Aβ 1-44 -
Genetics Company, Inc. monoclonal
IgG1
Mouse
(liquid, supernatant, PBS, azide, affinity purified)
- Dog, Human, Guinea Pig, Mouse, Rat, Cynomolgus C-terminal epitope mapping corr. to amino acid residues 33-42 of human Aβ peptide reacts with Aβ-peptide, aa 33-42; not Aβ 1-38, Aβ 1-39, Aβ 1-40, Aβ 1-43 or Aβ 1-44 -
Genetics Company, Inc. monoclonal
IgG1
Mouse
(liquid, supernatant, PBS, azide, affinity purified)
- Dog, Human, Guinea Pig, Mouse, Rat immunogen = Aβ 1-42 peptide at the C-terminus C-terminal of Aβ 1-42 peptide; not Aβ 1-38, Aβ 1-39, Aβ 1-40; low cross reactivity to Aβ 43 (10%)and Aβ 44 (13%) -
Innogenetics kit
Unknown Host
(well standardized multiparameter bead-based immunoassay for the simultaneous quantification of human ß-amyloid in plasma using xMAP® (registered trademark of Luminex Corp)technology)
- Human Uses 4G8 antibody;4G8 selectively binds juxtamembrane EC domain, aa 17-24; (epitope lies within aa 18-22) reactive to Aβ; for simultaneous quantification of different forms of β-amyloid in blood, with check for matrix interference -