Huntingtin (5A12)
HDB5A12(Greg MorrisN. E. Wales Institute)research group
monoclonal
IgG2a
-
Rabbit, Human, Mouse
immunogen at aa 2081-2086
Huntingtin
-
Huntingtin (5C12)
HDB5C12(Greg MorrisN. E. Wales Institute)research group
monoclonal
IgG2a
-
Rabbit, Human, Mouse
immunogen at aa 1844-2131
Huntingtin
-
Huntingtin (5E8)
HDA5E8(Greg MorrisN. E. Wales Institute)research group
monoclonal
IgG1
-
Rabbit, Human, Mouse
immunogen at aa 1171-1177
Huntingtin
-
Huntingtin (6B12)
HDA6B12(Greg MorrisN. E. Wales Institute)research group
monoclonal
IgG2a
-
Rabbit, Human, Mouse
immunogen at aa 977-1276
Huntingtin
-
Huntingtin (6F5)
HDA6F5(Greg MorrisN. E. Wales Institute)research group
monoclonal
IgG1
-
Rabbit, Human, Mouse
immunogen at aa 977-1276
Huntingtin
-
Huntingtin (7D2)
HDA7D2(Greg MorrisN. E. Wales Institute)research group
monoclonal
IgG1
-
Rabbit, Human, Mouse
immunogen at aa 1171-1177
Huntingtin
-
Huntingtin (7D7)
HDB7D7(Greg MorrisN. E. Wales Institute)research group
monoclonal
IgG2b
-
Rabbit, Human, Mouse
immunogen at aa 2081-2086
Huntingtin
-
Huntingtin (8A4)
HDC8A4(Greg MorrisN. E. Wales Institute)research group
monoclonal
IgG1
-
Rabbit, Human, Mouse
immunogen at aa 2703-2911
Huntingtin
-
Huntingtin (8G3)
HDC8G3(Greg MorrisN. E. Wales Institute)research group
monoclonal
IgG1
-
Rabbit, Human, Mouse
immunogen at aa 2703-2911
Huntingtin
-
Huntingtin (9B4)
HDC9B4(Greg MorrisN. E. Wales Institute)research group
monoclonal
IgG1
-
Rabbit, Human, Mouse
immunogen at aa 2703-2911
Huntingtin
-
Huntingtin
(Allan SharpeJohns Hopkins University)
polyclonal
(sera)
-
-
epitope mapped
-
Huntingtin
(Bill RichardsAmgen, Inc)
polyclonal
(antisera)
-
-
epitopes are peptides beginning at amino acids 1, 170, 331, 494, 560 and 654
-
Huntingtin
1893(H. Takano, J.F. GusellaHarvard/MGH)reference
polyclonal
Rabbit
(antisera)
-
Drosophila
immunogen = amino terminal aa 1-18
Huntingtin
-
Huntingtin
1894(H. Takano, J.F. GusellaHarvard/MGH)reference
polyclonal
Rabbit
(antisera)
-
Drosophila
immunogen = amino terminal aa 254-271
Huntingtin
-
Huntingtin(MW1-MW5)
(Jan Ko, Susan Ou and Paul H. Patterson, 216-76, Biology Division, California Institute of Technology)used in paper by Khoshman, 2002
monoclonal
-
Human, Mouse
expanded polyQ repeat form of Htt exon 1
HuntingtinMW1-MW5 show distinct staining patterns with WT and mutant transgenic mouse brains
-
Huntingtin(MW6)
(Jan Ko, Susan Ou and Paul H. Patterson, 216-76, Biology Division, California Institute of Technology)used in paper by Khoshman, 2002
monoclonal
-
Human, Mouse
polyQ domain of Htt exon 1
Huntingtin
-
Huntingtin(MW7)
(Jan Ko, Susan Ou and Paul H. Patterson, 216-76, Biology Division, California Institute of Technology)used in paper by Khoshman, 2002
monoclonal
-
Human, Mouse
polyP domain of Htt
Huntingtinstains htt in the perinuclear region as well in the nuclear inclusions formed by mutant htt; can differentiate transgenic from WT mice by staining nuclear inclusions in R6/2 brain
-
Huntingtin(MW8)
(Jan Ko, Susan Ou and Paul H. Patterson, 216-76, Biology Division, California Institute of Technology)used in paper by Khoshman, 2002
monoclonal
-
Human, Mouse
aa 83-90 of Htt
Huntingtincan differentiate transgenic from WT mice by staining nuclear inclusions in R6/2 brain
-
Huntingtin(-poly)
Huntingtin P7(JC Dorsman, MGC-Department of Human Genetics, Sylvius Laboratory, Leiden)used in paper by Peters, 2002
monoclonal
Rabbit
(affinity purified)
-
Human, Mouse
different segments of the N-term, C-term and central parts of the protein
Huntingtin
-
Huntingtin(-poly)
Huntingtin S830(JC Dorsman, MGC-Department of Human Genetics, Sylvius Laboratory, Leiden)used in paper by Peters, 2002
monoclonal
Sheep
(affinity purified)
-
Human, Mouse
different segments of the N-term, C-term and central parts of the protein
Huntingtin
-
Huntingtin (1A771)
Abcam
monoclonal
IgG1
Mouse
(liquid, PBS, azide, Protein G purified)
-
Human
Immunogen = fusion protein containing 62 glutamine amino acid repeats
377 kDa Huntingtin
-
Huntingtin (3H7/5)
AbD Serotec
monoclonal
IgG1
Mouse
(liquid, ascites, no preservative)
-
Human, Monkey, Hamster, Mouse, Rat
Immunogen = huntington fragment from aa 181-810 as a fusion protein
Huntingtin; no reaction with other proteins in WB
-
Huntingtin
Chemicon and Upstate are Millipore
monoclonal
IgG1
Mouse
(liquid, ascites, no preserves)
-
Human, Monkey, Mouse
immunogen = Huntingtin fragment from aa 2146-2541 as a fusion protein
Huntingtin Protein. No detectable cross reactivity to other proteins by WB
-
Huntingtin
Chemicon and Upstate are Millipore
monoclonal
IgG1
Mouse
(liquid, ascites, no preservative)
-
Human
immunogen = recomb. human huntingtin, amino acids 115-129.
reacts with huntingtin protein, amino acids 115-129. The antibody recognizes wild type and mutant huntingtin
-
Huntingtin
Chemicon and Upstate are Millipore
monoclonal
IgG1
Mouse
(liquid, ascites, no preservative)
-
Human
immunogen = recomb. human huntingtin, amino acids 1-82
reacts with huntingtin protein, aa 1-82. The antibody recognizes wild type and mutant huntingtin
-
Huntingtin (1HU-4C8)
Chemicon and Upstate are Millipore
monoclonal
IgG1
Mouse
(liquid, ascites, no preserves)
-
Rabbit, Human, Monkey, Hamster, Mouse, Rat
immunogen = Huntingtin fragment from aa 181-810 as a fusion protein
Huntingtin Protein. No detectable cross reactivity to other proteins by WB
-
Huntingtin (HU-4E6)
Chemicon and Upstate are Millipore
monoclonal
IgG2b ,κ
Mouse
(liquid, ascites, no preservative)
-
Human, Mouse
Immunogen = huntingtin fragment from aa 1247-1646 as a fusion protein
Huntingtin
-
Huntingtin (mHD549)
Chemicon and Upstate are Millipore
monoclonal
Ig
Rat
(liquid, ascites, azide)
-
Human, Monkey, Rat
immunogen = Huntingtin fusion protein 549-679, fused to Glutathione S-tranferase
Huntingtin protein residues 549-679
-
Huntingtin phos Ser421
Chemicon and Upstate are Millipore
polyclonal
Rabbit
(liquid, affinity purified Ig, phosphate, azide)
-
Human
Immunogen = synthetic peptide from human Huntingtin protein
Huntingtin phosphor at Serine 421; minimal reactivity with non-phosphor protein
-
Huntingtin
LifeSpan Biosciences, Inc.
monoclonal
Rabbit
(antigen affinity purified)
-
Human, Mouse, Rat
immunogen = synthetic peptide aa 416-424 of human huntingtin protein.
Huntingtin
-
Huntingtin
LifeSpan Biosciences, Inc.
monoclonal
Mouse
(ascites)
-
Human, Mouse
immunogen = huntingtin fragment from aa1247-1646 as a fusion protein
recombinant huntingtin; not suitable for natural huntingtin
-
Huntingtin
LifeSpan Biosciences, Inc.
monoclonal
Mouse
(DEAE-column chromatography)
-
Human, Monkey, Mouse, Rat
immunogen = huntingtin fragment from aa181-810 as a fusion protein
recombinant huntingtin; not suitable for natural huntingtin
-
Huntingtin
LifeSpan Biosciences, Inc.
monoclonal
Mouse
(ascites)
-
Human, Monkey
immunogen = huntingtin fragment from aa2146-2541 as a fusion protein
huntingtin
-
Huntingtin
LifeSpan Biosciences, Inc.
monoclonal
Rabbit
(supernatant)
-
Human
immunogen = synthetic peptide corresp. to residues specific to the apopain cleavage site of human huntingtin protein
huntingtin
-
Huntingtin
LifeSpan Biosciences, Inc.
monoclonal
Mouse
(IgG fractionation)
-
Rabbit, Human, Mouse
immunogen = recombinant protein corresp. to aa 1844 - 2131 of huntingtin
huntingtin
-
Huntingtin
LifeSpan Biosciences, Inc.
monoclonal
Mouse
(IgG fractionation)
-
Rabbit, Human, Mouse
immunogen = recombinant protein corresp. to aa 2703 - 2911 of huntingtin
huntingtin
-
Huntingtin
LifeSpan Biosciences, Inc.
monoclonal
Mouse
(IgG fractionation)
-
Rabbit, Human, Mouse
immunogen = recombinant protein corresp. to aa 997- 1276 of huntingtin
huntingtin
-
Huntingtin
LifeSpan Biosciences, Inc.
monoclonal
Rat
(ascites)
-
Mammal (various), Human
immunogen = huntingtin GST fusion protein aa549-679
huntingtin
-
Huntingtin
LifeSpan Biosciences, Inc.
polyclonal
Rabbit
(blue sepharose chromatography)
-
Human, Rat
immunogen = human peptide-hmw carrier
huntingtin
-
Huntingtin
LifeSpan Biosciences, Inc.
monoclonal
Mouse
(PBS, azide, protein G purified)
-
Human, Mouse
immunogen = recombinant fusion protein containing 62 glutamine aa repeat
huntingtin
-
Huntingtin
LifeSpan Biosciences, Inc.
monoclonal
Mouse
(protein G purified)
-
Human
immunogen = fusion protein containing 62 glutamine aa repeat
huntingtin
-
Huntingtin
LifeSpan Biosciences, Inc.
polyclonal
Rabbit
(DEAE-column chromatography)
-
Human
immunogen = synthetic peptide corresp. to aa 416-424 of the human huntingtin gene protein aa sequence: R S R S G-pS-I V E
huntingtin pS421
-
Huntingtin, N-term (mEM48)
Chemicon and Upstate are Millipore
monoclonal
IgG
Mouse
(liquid, supernatant, no preservative)
-
Human
Immunogen = GST fusion protein from the first 256 amino acids from human huntingtin with the deletion of the polyglutamine tract
Huntingtin protein (native and recomb.). Reacts with mutant huntingtin that express different numbers of repeats (82 to 150 glutamines), and different forms of mutant huntingtin.
-
Huntingtin
DSHB U. Iowa
monoclonal
IgG2b
Mouse
-
-
Immunogen = DRPLA-19Q, GST fusion protein
Huntingtin
-
Huntingtin
DSHB U. Iowa
monoclonal
IgM
Mouse
-
-
Immunogen = HD exon-1 with 67Q, GST fusion protein
Huntingtin
-
Huntingtin
DSHB U. Iowa
monoclonal
IgM
Mouse
-
-
Immunogen = GST fusion protein HD exon-1 with 67Q
Huntingtin
-
Huntingtin
DSHB U. Iowa
monoclonal
IgM
Mouse
-
Human
Immunogen = GST fusion protein (DRPLA-35Q)
Huntingtin
-
Huntingtin
DSHB U. Iowa
monoclonal
IgM
Mouse
-
-
Immunogen = HD exon-1 with 67 Q, GST fusion protein
Huntingin
-
Huntingtin
DSHB U. Iowa
monoclonal
IgM
Mouse
-
-
Immunogen = HD exon-1 with 67Q, GST fusion protein
Huntingtin
-
Huntingtin
DSHB U. Iowa
monoclonal
IgG2a
Mouse
-
-
Immunogen = HD exon-1 with 67Q, GST fusion protein
Huntingtin
-