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Antibodies

28 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
TAR DNA-binding protein /TDP-43 From labs (3)
N-terminal antibody(Virginia M.-Y. Lee, Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine)Reference: Winton, 2008 polyclonal
Rabbit
IB Human immunogen = synthetic peptide near the N-terminus of human TDP-43 corresp. to amino acid residues 6-24 TARDBP, N terminal -
C-terminal antibody(Virginia M.-Y. Lee, Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine)Reference: Winton, 2008 polyclonal
Rabbit
IB Human immunogen = an extreme C-terminal synthetic peptide, corresp. to the aa residues 394-414 of human TDP-43 TARDBP, C terminal -
Manuela Neumann monoclonal
IgG2a
Rat
(Cell culture supernatant)
ELISA, IB, IH, WB Human, Mouse immunogen = phosphopeptide pS409/410 (SMDSKS(p)S(p)GWG), corresponding to amino acids 404-413 of human TDP-43, coupled to BSA or ovalbumin. Detects C-terminal TDP-43 phosphorylated at serine 409 and 410. Does not react with the non-phosphorylated protein. By immunohistochemistry, labels a variety of TDP-43  inclusions, including neuronal cytoplasmic inclusions, dystrophic neurites, neuronal intranucelar inclusions, and glial cytoplasmic inclusions. Confirmed available Oct 2014
TAR DNA-binding protein /TDP-43 From manufacturers (25)
Proteintech Group, Inc. polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide, glycerol)
ELISA, IH, WB Human immunogen = full length 414 aa TARDBP protein detects TAR DNA binding protein -
Novus Biologicals monoclonal
IgG1
Mouse
(liquid, PBS, azide)
ELISA, IH, WB Human immunogen = recombinant human TARDBP (1-260aa) purified from E. coli detects TARDBP -
Novus Biologicals polyclonal
IgG
Rabbit
(affinity purified antisera, Tris-glycine, saline azide)
WB Primate (various), Chicken, Zebra fish, Human, Mouse, Xenopus immunogen = synthetic peptide to a C-terminal region (within residues 350-414) of the human TARDBP protein detects TARDBP, band is seen at ~45 kDa in WB -
Proteintech Group, Inc. polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide, glycerol)
ELISA, IH, WB Human, Mouse immunogen = TAR DNA binding protein, C-terminal 154aa of BC001487 detects 45kd full length protein and the truncated 25kd protein -
Abcam monoclonal
IgG1
Mouse
(liquid, protein-G purified, PBS, no preservative)
IC, IF, IH, WB Human immunogen = recombinant full length protein, corresponding to amino acids 1-261 of Human TARDBP 45kDa TARDBP -
Abcam polyclonal
IgG
Rabbit
(liquid, protein-A purified, sucrose, PBS, no preservative)
IH, WB Human immunogen = region within synthetic peptide: MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC, corresponding to N terminal amino acids 1-50 of Human TARDBP 45kDa TARDBP -
Abcam polyclonal
IgG
Rabbit
(liquid, Tween 20, saline, HEPES, EDTA, no preservative)
IC, IF, IP, WB Human immunogen = synthetic peptide: conjugated to KLH derived from within residues 350 to the C-terminus of Human TARDBP detects TARDBP -
Abcam polyclonal
IgG
Rabbit
(liquid, affinity purified, sucrose, PBS, no preservative)
ELISA, WB Human, Mouse immunogen = synthetic peptide: within residues GISVHISNAE PKHNSNRQLE RSGRFGGNPG GFGNQGGFGN SRGGGAGLGN , corresponding to internal sequence amino acids 251-300 of Human TARDBP detects TARDBP -
Abcam polyclonal
IgG
Rabbit
(liquid, affintiy purified, PBS, BSA, azide)
IC, IF, IH, WB Human, Rat immunogen = synthetic peptide: conjugated to KLH derived from within residues 250 - 350 of Human TARDBP detects TARDBP -
Abcam polyclonal
IgG
Rabbit
(liquid, affintiy purified, PBS, BSA, azide)
IC, IF, IH, WB Human, Mouse, Rat immunogen = synthetic peptide: conjugated to KLH derived from within residues 150-250 of Rat TARDBP detects TARDBP -
Abnova Corporation polyclonal
Rabbit
(liquid, Tris/glycine, saline, azide)
WB Chicken, Frog, Zebra fish, Human, Monkey, Mouse immunogen = a synthetic peptide selected within amino acids 350-414 of human TARDBP detects human TDP-43, cell lysate -
Abnova Corporation monoclonal
IgG1
Mouse
(liquid, PBS)
ELISA, WB Human immunogen = TARDBP (AAH01487, aa 1 ~261) full length recombinant protein with GST tag. recognizes human TDP-43, recombinant protein -
Abnova Corporation monoclonal
IgG1
Mouse
(liquid, PBS)
ELISA, IF, IH, WB Human immunogen = TARDBP (AAH01487, aa 1 ~261) full length recombinant protein with GST tag. (epitope at aa 205-222) recognizes aa 205–222 of human TDP-43, correspond. to a part of the second RNA recognition motif (RRM2);also recognizes 25 kDa C-terminal fragments -
Abnova Corporation monoclonal
IgG1
Mouse
(liquid, PBS, azide)
ELISA, IH, WB Human immunogen = recombinant protein corresponding to amino acids 1-260 of human TARDBP recognizes human TDP-43, recombinant protein -
Abnova Corporation polyclonal
Mouse
(liquid, glycerol)
ELISA, WB Human immunogen = TARDBP (AAH01487, aa 1 ~261) full length recombinant protein with GST tag. detects human TDP-43, cell lysate or recombinant protein -
Proteintech Group, Inc. monoclonal
IgG2b
Mouse
(liquid, purified, PBS, azide, glycerol)
ELISA, IH, WB Human immunogen = recombinant Protein recognizes 43kDa TARDBP -
Proteintech Group, Inc. monoclonal
IgG1
Mouse
(liquid, purified, PBS, azide, glycerol)
ELISA, IH, WB Human immunogen = recombinant Protein recognizes 45kDa TARDBP -
Cosmo Bio USA, Inc. polyclonal
Rabbit
(liquid, antiserum, azide)
ELISA, IH, WB Human immunogen = TDP-43 CMDSKS(p)S(p)GWGM, S(p):phosphoserine 409/410 recognizes 43kDa TARDBP only when phosphorylated at Serines 409 and 410; stains ubiquitin-positive inclusions in FTLD-U and ALS without nuclearstaining; does not stain ghost tangles and granulovacuolar degeneration in AD orother related diseases -
Cosmo Bio USA, Inc. monoclonal
IgG1
Mouse
(liquid, supernatant, azide)
ELISA, IH, WB Human immunogen = TDP-43 CMDSKS(p)S(p)GWGM, S(p):phosphoserine 409/410 recognizes 43kDa TARDBP only when phosphorylated at Serines 409 and 410; stains ubiquitin-positive inclusions in FTLD-U and ALS without nuclearstaining; does not stain ghost tangles and granulovacuolar degeneration in AD orother related diseases -
Cosmo Bio USA, Inc. polyclonal
Rabbit
(liquid, antiserum, azide)
ELISA, IH, WB Human immunogen = TDP-43 CMDSKS(p)S(p)GWGM, S(p):phosphoserine 409/410 recognizes 43kDa TARDBP only when phosphorylated at Serines 409 and 410; sometimes stains ghost tangles and dot-like structures (granulovacuolardegeneration) in the hippocampal and other regions of brains with AD or other relateddiseases. -
Cosmo Bio USA, Inc. polyclonal
Rabbit
(liquid, antiserum, azide)
ELISA, IH, WB Human immunogen = CMDSKS(p)SGWGM, S(p):phosphoserine 409 reacts with phosphorylated full-length TDP-43 at 45 kDa by WB; NCIs and DNs in dentate gyrus of FTLD-U -
Cosmo Bio USA, Inc. polyclonal
Rabbit
(liquid, antiserum, azide)
ELISA, IH, WB Human immunogen = CMDSKSS(p)GWGM, S(p):phosphoserine 410 reacts with phosphorylated full-length TDP-43 at 45 kDa by WB; NCIs and DNs in dentate gyrus of FTLD-U -
Proteintech Group, Inc. polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide, glycerol)
ELISA, IH, WB Human, Mouse, Rat immunogen = recombinant Protein (raised to aa 1-260) detects 43kDa TARDBP -
Cosmo Bio USA, Inc. polyclonal
Rabbit
(liquid, antiserum, azide)
ELISA, IH, WB Human, Rat immunogen = TDP-43 aa. 405-414, (CMDSKSSGWGM) recognizes the C-terminus of 43kDa TDP-43 -
Millipore
Cat# MABN14
monoclonal
IgG2ak
Rat
(Purified in buffer containing 0.1 M Tris glycine with 0.05% sodium azide)
ELISA, IB, IH, WB Human Ovalbumin-conjugated linear peptide corresponding to human TDP-43 phosphorylated at serine 409 and 410. This antibody recognizes human TDP-43 phosphorylated at serine 409 and 410. Confirmed Oct 2014