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Antibodies

47 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
CD11b, Integrins From manufacturers (47)
eBioscience monoclonal
IgG2b
Rat
(liquid, phosphate buffer, azide, PE-Cy5 conj.)
FC Mouse - specific for CD11b and Mac-1α /αM β2 integrin -
AbD Serotec monoclonal
IgG1
Mouse
(liquid, affinity purified IgG, azide)
FC, IH Rat immunogen = Rat spleen cell homogenate reacts with rat spleen cell homogenate; recognises small ramified microglia in the central nervous system -
ATCC monoclonal
IgM,κ
Mouse
(frozen liquid, Modified Dulbecco's medium, heat-inactivated gamma globulin free horse serum)
- Dog, Human, Rat immunogen = human acute monocytic leukemia cells (FAM M6) reacts with human CD11b, and blocks all known CD11b dependent activities in vitro -
ATCC monoclonal
IgG2a
Mouse
(frozen liquid, Modified Dulbecco's medium, heat-inactivated gamma globulin free horse serum)
- Primate (various), Human immunogen = human acute monocytic leukemia cells (FAM M6) reacts with human CD11b, and blocks a variety of CD11b dependent activities in vitro -
ATCC monoclonal
IgG1
Mouse
(frozen liquid, ATCC complete growth medium)
- Human immunogen = immunoprecipitates of human granulocyte lysates reacts with CD11b/MAC-1, and is specific for the alpha chain -
ATCC monoclonal
IgG2b
Mouse
(frozen liquid, ATCC-formulated Dulbecco's Modified Medium, fetal bovine serum)
- Human immunogen = human peripheral blood mononuclear cells (monocytes) reacts with CD11b -
R&D Systems monoclonal
IgG1
Mouse
(filtered, protein-G purified, PBS, trehalose, lyophilized)
FC, IH Human immunogen = mouse B cells detects Integrin αM -
R&D Systems monoclonal
IgG2B
Mouse
(filtered, protein-G purified IgG fraction, PBS, trehalose, lyophilized)
FC, IC Human immunogen = NS0-derived rhIntegrin αM extracellular domain detects Integrin αM -
R&D Systems monoclonal
IgG2B
Mouse
(liquid, ready to use, APC conj.)
FC Human immunogen = NS0-derived rhIntegrin αM extracellular domain detects Integrin αM -
R&D Systems monoclonal
IgG1
Mouse
(filtered, protein-G purified IgG fraction, PBS, trehalose, lyophilized)
ELISA, WB Human immunogen = NS0-derived rhIntegrin αM extracellular domain detects Integrin αM -
R&D Systems monoclonal
IgG1
Mouse
(filtered, protein-G purified, biotinylated, PBS, trehalose, lyophilized)
FC, IH Human immunogen = mouse B cells detects Integrin αM -
R&D Systems monoclonal
IgG2B
Mouse
(liquid, ready to use, Phycoerythrin conj.)
FC Human immunogen = NS0-derived rhIntegrin αM extracellular domain detects Integrin αM -
Chemicon and Upstate are Millipore monoclonal
IgG2c
Rat
(liquid, ascites)
FC, IH, IS Mouse immunogen = mouse integrin VLA-5 (alpha5beta1) from mouse embryonal carcinoma P19 cells detects Integrin α5/β1 -
Chemicon and Upstate are Millipore monoclonal
IgG3
Rat
(liquid, ascites, no preservatives)
FC, IH, IP, IS, WB Mouse immunogen = mouse embryonal carcinoma P19 cells with myeloma P3X63Ag9.653 cells detects Integrin α5/β1 -
Chemicon and Upstate are Millipore monoclonal
IgG2b
Rat
(liquid, protein-A purified)
FC, IP Pig, Human - detects Integrin α5/β1 -
Chemicon and Upstate are Millipore monoclonal
IgG2b
Rat
(liquid, ascites, no preservatives)
FC, IP, IS Mouse - detects Integrin α5/β1 -
Chemicon and Upstate are Millipore monoclonal
IgG1
Mouse
(liquid, ascites, unpurified, no preservatives)
IH, IP, IS Human, Monkey immunogen = Jurkat cells recognizes Integrin α5/β1 -
Chemicon and Upstate are Millipore monoclonal
IgG1
Mouse
(liquid, protein-A purified IgG, PBS, BSA, azide)
ELISA, IC, IH, IP, RIA Human immunogen = human renal carcinoma cell line (KJ29) Recognizes an epitope related to the VLA-3 complex (alpha-3/beta-1 integrin) -
R&D Systems monoclonal
IgG2B
Rat
(filtered, protein-G purified IgG fraction, PBS, trehalose, lyophilized)
FC, IH, IP Mouse immunogen = Con A-activated splenocytes recognizes Integrin αM -
R&D Systems monoclonal
IgG2B
Rat
(liquid, PBS, Carboxy fluorescein conj., azide)
FC Mouse immunogen = Con A-activated splenocytes recognizes Integrin αM -
R&D Systems monoclonal
IgG2B
Rat
(filtered, protein-G purified IgG fraction, PBS, BSA, biotinylated, lyophilized)
FC, IH, IP Mouse immunogen = Con A-activated splenocytes recognizes Integrin αM -
R&D Systems monoclonal
IgG2B
Rat
(liquid, PBS, Phycoerythrin conj., azide)
FC Mouse immunogen = Con A-activated splenocytes recognizes Integrin αM -
R&D Systems polyclonal
IgG
Goat
(filtered, affinity purified, PBS, trehalose, lyophilized)
ELISA, WB Human immunogen = NS0-derived rhIntegrin αM extracellular domain detects Integrin αM -
Novus Biologicals polyclonal
Rabbit
(liquid, antisera, Tris-glycine, saline, azide, affinity purified.Also available as HRP, Biotin or HiLyte Fluor™ 488 conj.)
IH, WB Human, Mouse immunogen = synthetic peptide made to an internal region (within residues 500-600) of the mouse CD11 (b/c) protein reacts with CD11; doublet is seen ~95 and 103 kDa in WB -
AbD Serotec monoclonal
IgG2a
Goat
(liquid, affinity purified, PBS, azideSee list of conjugates)
FC, IH, IP Rat immunogen = rat peritoneal macrophages reacts with the rat equivalent of human CD11b, the receptor for the iC3b component of complement; CD11b is expressed on most macrophages -
AbD Serotec monoclonal
IgG2b
Rat
(liquid, supernatant, Tris saline, calf serum, azideSee list of other formats)
FC, IH, IP Rabbit, Human, Mouse immunogen = T cell enriched splenocytes from B10 mice recognizes the murine CD11b cell surface antigen -
AbD Serotec monoclonal
IgG2b and IgG1
Rat
(PBS, BSA, azide, lyophilized, dual color, ALEXA FLUOR® 488 / RPE)
FC, IH Mouse immunogen = T cell enriched splenocytes from B10 mice recognizes murine CD115 and CD11b cell surface antigen -
AnaSpec polyclonal
Rabbit
(liquid, affinity purified, PBS, BSA, azide)
IF, IH, IP, WB Human, Hamster, Mouse, Rat immunogen = a synthetic peptide from the C-terminus of human integrin 5 subunit detects Integrin-β5 -
BD Pharmingen monoclonal
IgG2b
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 700 conj.)
FC Human, Mouse immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported -
BD Pharmingen monoclonal
IgG2b
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 647 conj.)
FC Human, Mouse immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported -
BD Pharmingen monoclonal
IgG2b
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 488 conj.)
FC Human, Mouse immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported -
BD Pharmingen monoclonal
IgG1
Mouse
(aqueous buffered solution, affinity purified, BSA, goat serum, azide)
IH Human immunogen = Human monocytes detects CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP. -
BD Pharmingen monoclonal
IgG1
Mouse
(liquid, affinity purified, aqueous buffered solution, azide, Pacific Blue™ conj.Also available APC-Cy™7 conj, #557754PE-Cy™5 conj, #555389PE-Cy™7 conj, #557743)
FC Human immunogen = Human monocytes reacts with CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP. -
BD Pharmingen monoclonal
IgG1
Mouse
(aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 488 conj.Also available Alexa Fluor® 700 conj, #557918)
FC Human immunogen = Human monocytes reacts with CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP -
BD Pharmingen monoclonal
IgG1
Mouse
(liquid, affinity purified, aqueous buffered solution, BSA, azide, R-PE conj.Also available Biotin Conj, #555387)
FC Human immunogen = Human monocytes reacts with CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP. -
BD Pharmingen monoclonal
IgG1
Mouse
(liquid, affinity purified, aqueous buffered solution, azide.Also available No azide/low endotoxin, #555385)
FC, IH Human immunogen = Human monocytes reacts with CD11b; significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP. -
BD Pharmingen monoclonal
IgG2b
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, APC-Cy7 conj.Also available PerCP-Cy5.5 conj, #550993PE-Cy™7 conj, #552850APC conj, #553312PE conj, #553311)
FC Human, Mouse immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported -
BD Pharmingen monoclonal
IgG2b
Rat
(aqueous buffered solution, affinity purified, stabilizer, azide, Biotin conj.Also available FITC conj, #553310)
FC Human, Mouse immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported -
BD Pharmingen monoclonal
IgG2b
Rat
(aqueous buffered solution, affinity purified, azideAlso available No azide/low endotoxin, #553307, for IP, blocking)
FC Human, Mouse immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes reacts with CD11b; reportedly blocks cell adherenceand C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes,polymorphonuclear leukocytes, and NK cells has been reported -
BD Pharmingen monoclonal
IgG2b
Rat
(affinity purified, IHC diluent containing serum and azide)
FC, IH Human, Mouse immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes detects CD11b; stains the macrophages, granulocytes, dendritic cells, and NK cells -
AbD Serotec monoclonal
IgG2b
Rat
(liquid, purified IgG, PBS, azideSee list of other formats)
FC, IH, IP Human, Mouse immunogen = Thioglycollate elicted Peritoneal Macrophages (TPM) recognizes mouse complement type 3 receptor (CR3) and precipitates a heterodimer of 165 and 95kD -
Chemicon and Upstate are Millipore monoclonal
IgG2b
Rat
(liquid, purified, PBS, azideAlso available Phycoerythrin conjugated, CBL1313P)
FC, IF, IH, IP Mouse immunogn = B10 mouse spleen cells enriched with T cells specific to CD11b; recognizes a differentiation antigen situated on mononuclear phagocytes and granulocytes; the expression of this antigen (Mac 1) increases during monocyte maturation -
Chemicon and Upstate are Millipore monoclonal
IgG2a
Mouse
(liquid, protein-A affinity purified, PBS, azide.Also available protein-G purified, PBS, no preservatives, CBL1512Z, or FITC conjugated, CBL1512F)
FC, IH, IP Rat immunogn = rat peritoneal macrophages recognizes most macrophages (including resident peritoneal and activated macrophages), Kupffer cells, but only about 35% of alveolar macrophages; also labels dendritic cells extensively, granulocytes and cells with the morphology of microglia in brain -
Chemicon and Upstate are Millipore monoclonal
IgG1
Mouse
(liquid, purified, PBS, BSA, azide.Also available Phycoerythrin conjugated, CBL145P)
FC, IH, IP, IS Baboon, Human, Monkey immunogn = synovial cells and human monocytes reacts with the integrin heterodimer of 165 kDa which comprises the CD11b receptor -
Chemicon and Upstate are Millipore monoclonal
IgG2b
Rat
(liquid, protein-G purified, PBS, no preservatives)
FC, IF, IH, IP, IS Human, Mouse immunogn = T cell enriched splenocytes from B10 mice recognizes the murine alphaM integrin chain; stains polymorphonuclear cells, monocytes and NK cells -
Chemicon and Upstate are Millipore monoclonal
IgG1
Mouse
(liquid, ascites, protein-A affinity purified, PBS, azide.)
IC, IH Rat immunogn = spleen cell homogenate with FCA recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes; recognizes small ramified (micro) glial cells in the central nervous system -
Chemicon and Upstate are Millipore monoclonal
IgG2a
Mouse
(liquid, purified, PBS, azide)
FC, IC, IH, IP, IS Human immunogn = leukemic cells of CML specific to CD11b; reacts with the CR3-receptor of inactivated C3b component of complement (C3bi) -