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Antibodies

209 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
Synucleins From labs (3)
(Mark Cookson,, NIA at NIH)used in paper by Sherer 2002 polyclonal
Rabbit
IC, WB -     -
(Virginia Lee, University of Pennsylvania, CNDR, Philadelphia, PA)used in paper by Kirik 2003 monoclonal
IgG
Mouse
IH -     -
γ-Synuclein Syn(Virginia Lee, University of Pennsylvania, CNDR, Philadelphia, PA)used in paper by Giasson, 2002 polyclonal
Rabbit
- -   γ-synuclein -
Synucleins From manufacturers (97)
Cell Signaling polyclonal
Rabbit
(affinity purified, liquid, HEPES, BSA, glycerol)
IP, WB Human, Monkey, Mouse, Rat immunogen = syntheticpeptide (KLH coupled) derived from the C-terminal seq. of human α-synuclein alpha isoform (18 kDa) of synuclein; the antibody may cross-react with beta-synuclein -
Li Starfish polyclonal
Rabbit
(azide, purified)
IH, IB Human, Rat synthetic peptide corresponding to residues [Cys],117-131of human α-synuclein  brain-derived α-synuclein. -
Covance Research Products, Inc (now BioLegend) monoclonal
IgG2a
Mouse
(raw ascites fluid)
IH, IP, WB Human immunogen = recombinant alpha synuclein α-synuclein, residues 1-130 -
Covance Research Products, Inc (now BioLegend) monoclonal
IgG
Mouse
(raw ascites fluid)
IH, WB Human immunogen = nitrated alpha synuclein nitrated α/β-synuclein, but does not react with nonnitrated α-synuclein; recognizes nitration on either residues Y125 or Y136 in α-synuclein -
Covance Research Products, Inc (now BioLegend) monoclonal
IgG
Mouse
(raw ascites fluid)
IH, WB Human immunogen = oxidized alpha synuclein recognizes native α-synuclein and nitrated/oxidized α-synuclein; some cross with β- and γ-synucleins -
Covance Research Products, Inc (now BioLegend) monoclonal
IgG2a
Mouse
(raw ascites fluid)
IH, IP, WB Zebra, Human, Mouse, Rat, Fish (various) immunogen = recombinant alpha and beta synuclein α- and β-synuclein, residues 130-140 -
A B R - Thermo Scientific polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
IH Human, Rat immunogen = synthetic peptide from human C-terminal aa sequence (commercially sensitive) α-Synuclein -
A B R - Thermo Scientific monoclonal
IgG2a
Mouse
(liquid,PBS, BSA, azide, protein A purified)
WB Human immunogen = recombinant full length human alpha-synuclein α-Synuclein -
A B R - Thermo Scientific polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
IH, WB Human, Rat immunogen = A synthetic peptide corresponding to near N-terminal of human α, β, pan-synuclein protein pan-Synuclein -
Biosource Invitrogen polyclonal
Rabbit
IH, WB Human, Rat - α-synuclein -
Zymed/ Invitrogen monoclonal
IgG1 κ
Mouse
(liquid, PBS, azide, affinity purified)
ELISA, IH, IP, WB Human immunogen = recombinant human α-synuclein αsynuclein; not β- or γ-synuclein or synoretin -
Biosource Invitrogen polyclonal
Goat
(liquid, whole serum, azide)
ELISA, IH Human immunogen = synthetic peptide M P V D P D N E A Y E M P S E E corresp. to aa 116-131 of C-terminus of human α-synuclein. the C-terminus of α-synuclein -
Biosource Invitrogen monoclonal
IgG1
Mouse
(liquid, affinity purified IgG, PBS, BSA, azide)
ELISA, IH, WB Human immunogen = recombinant human α-synuclein, aa 121-125 19 kDa protein, α-synuclein -
Cambio monoclonal
IgG1
Mouse
(IHC Concentrate)
IH, WB Human immunogen = Lewy bodies purified from patients sufferingfrom DLB  α-synuclein, and not β-synucleinor γ-synuclein -
Zymed/ Invitrogen monoclonal
IgG2a
Mouse
(affinity purified, liquid, PBS, azide)
IF, IH, IP, WB Human, Mouse immunogen = recombinant human α- and β-synuclein both α-and β-synuclein; not γ-synuclein or synoretin -
Biomol Enzo Life Sciences polyclonal
Rabbit
(liquid, PBS, azide, affinity purified)
IH, IP, WB Human, Mouse, Rat immunogen = a synthetic peptide corresponding to residues 97-111 of human β-synuclein. β-synuclein -
Biomol Enzo Life Sciences polyclonal
Rabbit
(liquid, PBS, azide)
IH, IP, WB Human, Rat immunogen = a synthetic peptide corresponding to residues 117-131 of human α-synuclein. α-synuclein -
A B R - Thermo Scientific polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
IH Human, Rat immunogen = synthetic peptide from human C-terminal aa sequence (commercially sensitive) β-Synuclein -
A B R - Thermo Scientific polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified, pre-diluted)
IH Human, Rat immunogen = synthetic peptide from human C-terminal aa sequence (commercially sensitive) β-Synuclein -
EMD Biosciences, Inc. polyclonal
Guinea Pig
(liquid, serum)
IF, IH, WB Bovine, Human, Mouse, Rat immunogen = synthetic peptide (E A Y E M P S E E G Y Q D Y E P E A) aa. 123-140 of the C-terminal of the cloned rat α-synuclein α-synuclein -
EMD Biosciences, Inc. polyclonal
Goat
(liquid, neat serum, no preservative)
ELISA, IH Human, Mouse, Rat immunogen = synthetic peptide (M P V D P D N E A Y E M P S E E) corresp. to aa 116-131 of human α-synuclein, conj. to KLH α-synuclein -
Fitzgerald polyclonal
Goat
(Neat serum, no preservatives)
ELISA, IH, WB Human immunogen = synthetic peptide equiv. to aa. 116-131 of C-terminal of PD human α-synuclein C-terminus aa. 116-131 of α-synuclein -
Accurate monoclonal
Mouse
(lyophilized, supernatant)
IH Human   α-Synuclein not β-Synuclein -
Accurate monoclonal
Mouse
(supernatant)
IH Human   α-Synuclein not β-Synuclein -
Accurate monoclonal
Mouse
ELISA, IH, WB Human, Mouse, Rat   α-Synuclein -
A D I monoclonal
IgG1
Rabbit
(neat or affinity purified; control peptide available)
ELISA, WB Human immunogen = recombinant human synuclein-alpha protein α-Synuclein -
A D I polyclonal
Rabbit
(neat or affinity purified, control peptide)
ELISA, IF, IH, IP, WB Rat immunogen = 19 aa peptide locating near the C-terminus of human synuclein-alpha, form 2 rat-α-synuclein form 2; not forms 1 or 3, and not β-Synuclein -
A D I polyclonal
Rabbit
(neat or affinity purified, control peptide)
ELISA, IF, IH, IP, WB Human, Rat immunogen = 15 aa peptide of human synuclein-beta Syn1 located at C-terminal β-synuclein; not α-Synuclein -
Axxora monoclonal
IgG1
Mouse
(frozen)
ELISA, IC, IH, WB Human immunogen = purified human α-synuclein produced in E. coli α-synuclein; no cross with β- and γ-synucleins -
Axxora monoclonal
IgG1
Mouse
(frozen)
ELISA, IH, WB Human, Mouse, Rat immunogen = purified human α-synuclein produced in E. coli α-synuclein; no cross with β- or γ-synucleins -
Axxora monoclonal
IgG1
Mouse
ELISA, IH, WB Human immunogen = synthetic peptide corresp. to aa 115-122 of human α-synuclein α-synuclein -
Autogen Bioclear polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified; blocking peptide [sc-7012P])
IF, WB Human, Mouse, Rat immunogen = peptide mapping at the N-terminus of human α-synuclein α-synuclein and β-synuclein -
Autogen Bioclear polyclonal
IgG
Goat
(liquid, PBS, azide, gelatin, affinity purified; blocking peptide [sc-7011P]; rabbit antibody [sc-7011R])
IF, IP, WB Human, Mouse, Rat immunogen = C-terminus of human α-synuclein α-synuclein; no cross with β-synuclein -
Autogen Bioclear monoclonal
IgG1
Mouse
(liquid, PBS, gelatin, azide)
IF, IP, WB Human immunogen = aa 121-125 of human α-synuclein α-synuclein -
Autogen Bioclear polyclonal
Rabbit
(neat serum, thimerosal or merthiolate)
ELISA, IF, IH, IP, WB Human, Mouse, Rat immunogen = 15 aa peptide near C-terminus of human α-synuclein α-synuclein -
Autogen Bioclear monoclonal
IgG2a, κ
Mouse
(liquid, PBS, BSA, azide, Protein A purified)
WB Human immunogen = human recombinant α-synuclein α-synuclein; not β- or γ-synuclein -
Autogen Bioclear polyclonal
Rabbit
(neat serum, thimerosal or merthiolate)
ELISA, IF, IH, IP, WB Mouse, Rat immunogen = 19 aa peptide near C-terminus of rat α-synuclein form 2 α-synuclein, form 2; not forms 1or 3; not β-synuclein -
Autogen Bioclear polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified; blocking peptide [sc-10698P])
IF, WB Human, Mouse, Rat immunogen = peptide mapping within an internal region of human γ-synuclein γ-synuclein -
Autogen Bioclear polyclonal
Rabbit
(liquid, affinity purified)
ELISA, WB Human - β-synuclein -
Autogen Bioclear polyclonal
Rabbit
(liquid, affinity purified)
ELISA, WB Human - β-synuclein -
Autogen Bioclear polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified; blocking peptide [sc-10699P])
IF, WB Human immunogen = peptide mapping at the C-terminus of human γ-synuclein γ-synuclein -
Autogen Bioclear monoclonal
IgG2a
Mouse
(liquid, PBS, gelatin, azide)
IF, IP, WB Human immunogen = human recombinant α-synuclein α-synuclein -
Autogen Bioclear polyclonal
IgG
Rabbit
(PBS, gelatin, azide)
IF, IP, WB Human, Mouse, Rat immunogen = recombinant protein corresp. to a a 1-140 representing full length human α- β- and γ-synuclein α-, β- and γ-synuclein -
Autogen Bioclear monoclonal
IgG
Mouse
(liquid, PBS, gelatin, azide)
IF, WB Human immunogen = oxidized human α-synuclein nitrated α-synuclein -
Novocastra monoclonal
IgG1
Mouse
(liquid, supernatant, azide)
IH - immunogen = prokaryotic recombinant protein corresp. to the full length α-synuclein α-synuclein (Lewy body and neuropil); not β-synuclein -
Novocastra monoclonal
IgG1
Mouse
(lyophilized, supernatant, azide)
IH - immunogen = prokaryotic recombinant protein corresp. to the full length α-synuclein α-synuclein (Lewy body and neuropil); not β-synuclein -
Novocastra monoclonal
IgG2a
Mouse
(liquid, supernatant, azide)
IH Human - γ-synuclein -
R&D Systems monoclonal
IgG1
Goat
(supernate, protein-G, PBS, trehalose, filtered, lyophilized)
ELISA, WB Human immunogen = purified E. coli-derived recombinant human alpha-synuclein α-synuclein -
R&D Systems polyclonal
IgG
Goat
(affinity purified, PBS, trehalose, filtered, lyophilized)
ELISA, IH, WB Human immunogen = purified E. coli-derived recombinant human alpha-synuclein α-synuclein -
R&D Systems polyclonal
IgG
Goat
(affinity purified, Biotin, PBS, BSA, filtered, lyophilized)
WB Human immunogen = purified E. coli-derived recombinant human alpha-synuclein α-synuclein -
RDI /Fitzgerald polyclonal
Goat
(liquid, whole serum)
ELISA, IH Human immunogen = synthetic peptide M P V D P D N E A Y E M P S E E that corresponds to aa. 116-131 of C-terminus of human α-synuclein α-synuclein (Lewy bodies) -
Autogen Bioclear monoclonal
IgG1
Mouse
(liquid, PBS, gelatin, azide)
IF, WB Human immunogen = recombinant human α-synuclein nitrated in vitro nitrated α- and β- synuclein -
Signet Covance monoclonal
IgG1
Mouse
(frozen, supernatant, no preservative)
DB, IH, WB Human immunogen = purified human α-synuclein produced in E. coli α-synuclein; no cross with β- and γ-synuclein -
Signet Covance monoclonal
IgG1
Mouse
(frozen, PBS, no preservative)
IH, WB Human, Mouse, Rat immunogen = purified human α-synuclein produced in E. coli α-synuclein; no cross reaction with β or γ-synuclein -
Signet Covance monoclonal
IgG1
Mouse
(liquid, PBS, no preservative, protein G purified)
DB, ELISA, IH, WB Human immunogen = synthetic peptide corresp. to aa 115-122 of human α-synuclein α-synuclein -
Amersham GE Healthcare kit
Unknown Host
ELISA - - specific for synuclein; measures whole protein and peptide fragment 117-131 -
Abcam monoclonal
IgG2a
Mouse
(liquid, ascites, no preservative)
IH, IP, WB Human immunogen = recombinant human α- and β- synuclein recognises residues 130-140 in α- and β- synuclein -
Abcam monoclonal
IgG1
Mouse
(liquid, precipitated and dialyzed supernate, PBS, azide)
DB, ELISA, IH, WB Human immunogen = recomb. human alpha synuclein, produced in E. coli α-Synuclein -
Abcam monoclonal
IgG1
Mouse
(liquid, precipitated and dialyzed supernate, PBS, no preservative)
ELISA, IH, WB Human, Mouse, Rat immunogen = recomb. human alpha synuclein, produced in E. coli α-Synuclein -
Abcam monoclonal
IgG1
Mouse
(liquid, PBS, no preservative, protein G purified)
ELISA, IH, WB Human immunogen = Lewy bodies purified from patients suffering dementia with Lewy bodies α-Synuclein; epitope located in region encoded by aa 115-122 -
Abcam monoclonal
IgG
Mouse
(liquid, ascites, PBS, BSA, glycerol, azide, affinity purified)
IH, WB Human immunogen = full length protein human, nitrated synuclein reacts with nitrated α-synuclein (either Y125 or Y136) as well as β-synuclein but does not react with nonnitrated α-synuclein -
Abcam monoclonal
IgG2a
Mouse
(liquid, protein-A purified, PBS, BSA, azide)
WB Human immunogen = recomb. full length human alpha synuclein highly specific for α-synuclein and does not react with beta and gamma synucleins -
Abcam monoclonal
IgG
Mouse
(liquid, ascites, no preservative)
IH, WB Human immunogen = full length protein human, oxidized alpha synuclein recognises native and nitrated/oxidized α-synuclein; some cross-reactivity with β and γ synucleins -
Abcam polyclonal
IgG
Sheep
(liquid, affinity purified)
IH, WB Rodent (various), Human, Mouse, Rat immunogen = synthetic peptide M P V D P D N E A Y E M P S E E (aa 116-131) of human α-synuclein coupled to diphtheria toxoid with a cysteine residue attached to the N-terminal of the peptide alpha synuclein -
Abcam polyclonal
IgG
Goat
(whole antiserum, no preservative)
ELISA, IH, WB Human immunogen = synthetic peptide (aa 116-131) on the C-terminus of human alpha synuclein peptide α-Synuclein C-terminal -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
IH Human, Rat immunogen = synthetic peptide: G I L E D M P V D P D N E A Y E M P S E E, corresp. to C-terminal aa 111-131 of human alpha synuclein alpha Synuclein; not beta synuclein -
Abcam polyclonal
IgG
Sheep
(liquid, whole antiserum, filtered)
IH, WB Human immunogen = synthetic peptide: A K E G V V A A A E T K Q G V, corresp. to aa 11-26 of human alpha synuclein alpha Synuclein -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified; prediluted)
IH Human, Rat immunogen = synthetic peptide: G I L E D M P V D P D N E A Y E M P S E E, corresp. to C-terminal aa 111-131 of human alpha synuclein alpha Synuclein; not beta synuclein -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
ELISA Human, Mouse, Rat immunogen = synthetic peptide derived from within residues 100 to the C-terminus of human α- synuclein, phosphorylated at Y125, conjugated to KLH alpha Synuclein phosphorylated on Y125 -
Abcam polyclonal
IgG
Rabbit
(liquid, whole antiserum, no preservative)
DB, IC, IH, WB Human immunogen = synthetic peptide (I E P L M E P E G S Y E D P P Q E) corresp. to the C-terminal of human β-synuclein (108- 125), conj. to diphtheria toxoid β- synuclein; -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
IH Human, Rat immunogen = synthetic peptide from region of human C-terminal (the aa sequence is considered to be commercially sensitive) β- synuclein; no cross-reactivity with α- or γ- synuclein -
Abcam polyclonal
IgY
Chicken
(liquid, PBS, no preservative, affinity purified)
WB Human immunogen = fusion protein, corresp. to a.a. 1-134 of human beta Synuclein β- synuclein -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
IH Human, Rat immunogen = synthetic peptide from region of human C-terminal (the aa sequence is considered to be commercially sensitive) β- synuclein; no cross-reactivity with α- or γ- synuclein -
Abcam polyclonal
IgG
Sheep
(liquid, whole antiserum)
IH Rodent (various), Human, Rat immunogen = synthetic peptide I E P L M E P E G E S Y E D P P Q E corresp. to the C-terminal seq. of human beta-synuclein (108-125) coupled to diphtheria toxoid β- synuclein -
Abcam polyclonal
IgG
Sheep
(liquid, tris-HCl saline, no preservative, affinity purified)
IH Rodent (various), Human, Rat immunogen = synthetic peptide I E P L M E P E G E S Y E D P P Q E corresp. to the C-terminal seq. of human beta-synuclein (108-125) coupled to diphtheria toxoid β- synuclein -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, thimerosal, protein A purified)
ELISA, WB Human immunogen = recombinant human full length protein purified from E. coli β-synuclein; no cross reactivity with α- or γ- synuclein -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, azide, protein A purified)
IH Human, Rat immunogen = synthetic peptide (Human) (C terminal) β-synuclein; no cross reactivity with α- or γ- synuclein -
Abcam polyclonal
IgG
Rabbit
(liquid, whole antiserum)
DB, IF, IH, WB Human, Rat immunogen = synthetic peptide E K E E V A E E A Q S G G D corresp. to aa 114-127 of the human γ- synuclein protein γ- synuclein; high level of specificity -
Abcam polyclonal
IgG
Rabbit
(liquid, whole antisera)
IH, WB Human, Rat immunogen = synthetic peptide A K E G V V A A A E K T K Q G V corresp. to aa 11- 26 of the human α, β and γ synuclein protein residue recognizes all three forms of synuclein -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
IH, WB Human, Rat immunogen = synthetic peptide corresp. to near N-terminal of human α, β and γ synuclein protein recognizes all three forms of synuclein -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified, prediluted)
IH Human, Rat immunogen = synthetic peptide corresp. to near N-terminal of human α, β and γ synuclein protein recognizes all three forms of synuclein -
Abcam polyclonal
IgG
Rabbit
(liquid, serum, BSA, Hepes, glycerol, affinity purified, no preservative)
WB Rat immunogen = phosphopeptide corresp. to aa. residues surrounding the phospho serine 129 of Rat α-synuclein 15 kDa alpha Synuclein phosphorylated at Serine 129 -
Abcam monoclonal
Mouse
(liquid, ascites)
ELISA, IH, WB Human immunogen =Ni-NTA purified truncated recombinant human alpha Synuclein expressed in E. coli strain BL21 (DE3) α-Synuclein; cytoplasmic and nuclear; membrane bound in dopaminergic neurons -
Abcam polyclonal
IgG
Sheep
(liquid, filtered serum, no preservative)
IH, WB Human immunogen = synthetic peptide: A K E G V V A A A E K T K Q G V, corresp. to aa 11-26 of human α- Synuclein α- Synuclein -
Axxora monoclonal
rat IgG2a
Rat
IH, IP, WB Human immunogen = synthetic peptide corresp. to aa 116-131 of human α-synuclein α-synuclein; not recombinant β- or γ-synuclein. -
AbD Serotec polyclonal
Goat
(liquid, serum, azide)
ELISA, IH Human immunogen = synthetic peptide corresp. to aa 116-131 of the C-terminus of a synuclein α-Synuclein -
AbD Serotec monoclonal
IgG1
Mouse
(liquid, Ig fraction, PBS, azide)
ELISA, IH, WB Human, Mouse, Rat immunogen = recombinant human alpha-synuclein α-Synuclein -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified; blocking peptide [sc-7012])
IF, WB Human, Mouse, Rat immunogen = peptide mapping at the N-terminus of human α-synuclein α-synuclein and β-synuclein -
Santa Cruz monoclonal
IgG2a
Mouse
(liquid, PBS, gelatin, azide])
IF, IP, WB Human, Mouse, Rat immunogen = recombinant human α/β-synuclein α-synuclein and β-synuclein -
Santa Cruz monoclonal
IgG2a
Mouse
(liquid, PBS, gelatin, azide)
IF, IP, WB Human immunogen = recombinant human α-synuclein α-synuclein -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified; blocking peptide [sc-9565P])
IF, WB Human, Mouse, Rat immunogen = peptide mapping at the C-terminus of human β-synuclein β-synuclein -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified; blocking peptide [sc-9564P])
IF, WB Human, Mouse, Rat immunogen = peptide mapping at the C-terminus of human β-synuclein β-synuclein -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified; blocking peptide [sc-10699P])
IF, WB Human immunogen = peptide mapping at the C-terminus of human γ-synuclein γ-synuclein -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified; blocking peptide [sc-10698P])
IF, WB Human, Mouse, Rat immunogen = peptide mapping within an internal region of human γ-synuclein γ-synuclein -
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, gelatin, azide)
IF, IP, WB Human immunogen = recombinant human α-synuclein nitrated in vitro nitrated α- and β- synuclein -
Santa Cruz monoclonal
IgG
Mouse
(liquid, PBS, gelatin, azide)
IF, WB Human immunogen = oxidized human α-synuclein nitrated α-synuclein -
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, gelatin, azide)
IF, IH, WB Human immunogen = purifiedtruncated recomb. α-synuclein of human origin α-synuclein, 19kDa -