Antibody

sAPPβ-wild type

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Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Methods: IP, WB
Source: I B L - Hamburg GmbH
Cat# JP18957
References:
Ho, 2009
Schmidt, 2007
Formulation: lyophilized, BSA, PBS, azide, purified
Reactivity:
Reacts in: Human

Immunogen/Epitope

immunogen = synthetic peptide in portion of C-terminus of human sAPPβ-Wild Type
(I S E V K M)

Specificity

detects sAPP-Wild type which is clevaged by β-secretase; no cross with sAPPα or full-length APP

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References

Paper Citations

  1. . Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease. J Neurosci. 2008 Dec 31;28(53):14392-400. PubMed.
  2. . SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1. J Biol Chem. 2007 Nov 9;282(45):32956-64. PubMed.

Further Reading

No Available Further Reading