Antibody
RAGE
Quick Links
Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: Abcam
cat # ab3611
Reference:
Takeda, S, 2010
Formulation: liquid, affinity purified, PBS, BSA, azide
Reactivity:
Reacts in: Mouse, Rat
others not tested
Immunogen/Epitope
immunogen = synthetic peptide, (C)W R K R Q P(R/L) E E R K A P E S Q E D (N), corresp. to aa 362-380 of rat RAGE
Specificity
RAGE
References
Paper Citations
- Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R. Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7036-41. PubMed.
Further Reading
News
- Enhancing Peripheral Sink Scours Brain of Amyloid
- Chicago: Lilly’s Antibody Appears to Do No Harm, But Will It Help?
- Macrophages Storm Blood-brain Barrier, Clear Plaques—or Do They?
- DC: Funding We Can Believe In? Perhaps, But Scientists Must Advocate
- DC: Primate, Mouse Studies Sustain Aβ Immunotherapy Hopes
Comments / Questions
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