Antibody

PS-1 NTF

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Clonality: polyclonal
Host: Rabbit
Methods: WB
Source: antibodies 95/23 and 98/1
(Janetta Culvenor,
Department of Pathology, The University of Melbourne, Victoria, Australia)
used in paper by Runz, 2002

Immunogen/Epitope

epitope at PS1, aa 1-20

Specificity

PS1 in human neuroblastoma SH-SY5Y wild type and PS1 transfectants (SY5Y-PS1) as well as in mouse P19, in CHO-K1 and CHO-APP770 transfected cells, in rat cerebellar granule and hippocampal neurons, and astrocytes. 50 kDa and 30 kDa presumptive cleavage product in WB

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References

Paper Citations

  1. . Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells. J Neurosci. 2002 Mar 1;22(5):1679-89. PubMed.

External Citations

  1. Janetta Culvenor
  2. Department of Pathology, The University of Melbourne, Victoria, Australia

Further Reading

No Available Further Reading