Antibody

Progranulin

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Clonality: polyclonal
Host: Goat
Isotype: IgG
Methods: ELISA, IH, WB
Source: R&D Systems
Cat# AF2420
Reference:
Rademakers, 2008
Formulation: affinity purified, filtered, PBS, trehalose, lyophilized
Reactivity:
Reacts in: Human

Immunogen/Epitope

immunogen = purified, NS0-derived, recomb. human Progranulin (rhProgranulin)

Specificity

recognizes human progranulin. In direct ELISAs and WB, 30% cross-reactivity with rmProgranulin

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References

Paper Citations

  1. . Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia. Hum Mol Genet. 2008 Dec 1;17(23):3631-42. PubMed.

Further Reading

No Available Further Reading