Antibody

Presenilin-1, N-terminal

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Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Methods: IF, IP, WB
Source: Calbiochem EMD Biosciences
Cat# 529591
References:
Pavlov PF, 2010
Heneka, 2010
Formulation: liquid, undiluted serum, no preservative
Reactivity:
Reacts in: Human, Monkey, Mouse, Rat

Immunogen/Epitope

immunogen = recomb. protein containing aa 1-65 of human presenilin 1 fused to GST

Specificity

Recognizes the presenilin 1 (1-65) holoprotein and its N-terminal fragments

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References

Paper Citations

  1. . Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein. FASEB J. 2011 Jan;25(1):78-88. PubMed.
  2. . Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6058-63. PubMed.

Further Reading

No Available Further Reading