Antibody

p53 (DO-12)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG2b
Source: RDI /Fitzgerald
Cat# CBL773
Formulation: ascitic fluid, protein-A purified, PBS, BSA, azide
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

epitope between aa 250 and 270, which is located between conserved domain IV and V on an exposed turn of the protein structure

Specificity

reacts with human p53 protein, wild type and mutant forms under denaturing conditions; reacts with mutant form under non-denaturing conditions but not with wild-type

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