Antibody

LR11 /SorLA-1 (48/LR11)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG2a
Methods: WB
Source: BD Transduction
Cat# 611860, 50 µg
611861, 150 µg
References:
(unspecified formulation, see also 612633,
Lane RF, 2010
Vieira SI, 2010
Julien, 2008 )
Formulation: Aqueous buffered solution, BSA, glycerol, azide, affinity purified<br />See also Cat# 612663 for IH
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

Immunogen = human LR11 (aa. 1220-1337)

Specificity

detects LR11; 250 kDa by WB

Note

not IF

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References

Paper Citations

  1. . Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex. J Neurosci. 2010 Sep 29;30(39):13110-5. PubMed.
  2. . Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated. Mol Neurodegener. 2010;5:40. PubMed.
  3. . High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model. Neurobiol Aging. 2010 Sep;31(9):1516-31. PubMed.

Further Reading

No Available Further Reading