Antibody

Lamin-A

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Clonality: polyclonal
Host: Rabbit
Methods: IB, IF
Source: Sigma Aldrich
Cat# L1293
Reference:
D'Angelo, 2009
Formulation: liquid, affinity isolated, PBS, azide
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

immunogen = synthetic peptide corresp. to amino acid residues
598-611 of human lamin A with a C-terminal added
cysteine, conj. to KLH, as immunogen

Specificity

recognizes lamin A. (~ 70 kDa); additional bands at 45-50 kDa may appear in some preparations, which may represent cleaved fragments of lamin A; antibody does not recognize lamin C

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References

Paper Citations

  1. . Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells. Cell. 2009 Jan 23;136(2):284-95. PubMed.

Further Reading

No Available Further Reading