Antibody

Insulin Receptor (Ab-3) (29B4)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Methods: IP, Neut
Source: Calbiochem EMD Biosciences
Cat# GR07
Reference:
Townsend, 2007
Formulation: liquid, phosphate buffer, gelatin, azide
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

immunogen = partially purified, human, placental insulin receptor

Specificity

detects insulin receptor; antibody has been reported to produce partial inhibition of insulin dependent protein tyrosine kinase activity (see application references). Also reported to cross-react with IGF-I receptor

Note

not IB or IH(P)

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References

Paper Citations

  1. . Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. J Biol Chem. 2007 Nov 16;282(46):33305-12. PubMed.

Further Reading

No Available Further Reading