Antibody

α-II-Spectrin /Fodrin (AA6)

Tools

Back to the Top

Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Methods: IH, IP, WB
Source: Chemicon and Upstate are Millipore
Cat# MAB1622
References:
Rao, 2008
Trinchese, 2008
Formulation: liquid, PBS,BSA, azide
Reactivity:
Reacts in: Rabbit, Chicken, Pig, Human, Guinea Pig, Mouse, Rat

Immunogen/Epitope

Immunogen = purified Chicken red blood cell membranes

Specificity

240 kDa α-II-spectrin/fodrin of all mammalian nonerythroid cells and chicken alpha-spectrin. Antibody will all recognize caspase (150kDa, 120kDa) and calpain cleavage (150kDa) products of alpha fodrin

Note

not IH(P)

Comments / Questions

Make a comment or submit a question

To make a comment you must login or register.

Comments on this content

No Available Comments

References

Paper Citations

  1. . Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression. J Neurosci. 2008 Nov 19;28(47):12241-54. PubMed.
  2. . Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease. J Clin Invest. 2008 Aug;118(8):2796-807. PubMed.

Further Reading

No Available Further Reading