Antibody

Huntingtin phos Ser421

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Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Source: Abcam
Cat# ab2174
Formulation: liquid, KPO4-saline, azide, affinity purified
Reactivity:
Reacts in: Human
expect pig

Immunogen/Epitope

immunogen =
synthetic peptide: R S R S G pS I V E, corresp. to aa 416-424 of human Huntingtin

Specificity

detects a 190kDa band in PC-3 cells, which may correspond to Huntingtin. Stains neuronal cytoplasm in IH; specificity for phospho S421 Huntingtin is inconclusive

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