Antibody

GluR2 (6C4)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG2a
Methods: ELISA, IC, IH, IP, RIA, WB
Source: Chemicon and Upstate are Millipore
Cat# MAB397
Reference:
Nakamoto, 2007
Peineau, 2007
Formulation: supernate, protein-A affinity purified, PBS, no preservative
Reactivity:
Reacts in: Dog, Human, Monkey, Rat

Immunogen/Epitope

Immunogen = recomb. fusion protein TrpE-GluR2 (N-terminal portion, amino acids 175-430 of rat GluR2)

Specificity

recognizes large N-terminal extracellular domain of GluR2. No cross-reactivity observed with other AMPA /Kainate GluR subunits.

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References

Paper Citations

  1. . Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15537-42. PubMed.
  2. . LTP inhibits LTD in the hippocampus via regulation of GSK3beta. Neuron. 2007 Mar 1;53(5):703-17. PubMed.

Further Reading

No Available Further Reading