Antibody

GluR2 (6C4)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG2a
Source: Chemicon and Upstate are Millipore
Cat# MAB397
Reference:
Nakamoto, 2007
Peineau, 2007
Formulation: supernate, protein-A affinity purified, PBS, no preservative
Reactivity:
Reacts in: Dog, Human, Monkey, Rat

Immunogen/Epitope

Immunogen = recomb. fusion protein TrpE-GluR2 (N-terminal portion, amino acids 175-430 of rat GluR2)

Specificity

recognizes large N-terminal extracellular domain of GluR2. No cross-reactivity observed with other AMPA /Kainate GluR subunits.

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References

Paper Citations

  1. Nakamoto M, Nalavadi V, Epstein MP, Narayanan U, Bassell GJ, Warren ST. Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15537-42. PubMed.
  2. Peineau S, Taghibiglou C, Bradley C, Wong TP, Liu L, Lu J, Lo E, Wu D, Saule E, Bouschet T, Matthews P, Isaac JT, Bortolotto ZA, Wang YT, Collingridge GL. LTP inhibits LTD in the hippocampus via regulation of GSK3beta. Neuron. 2007 Mar 1;53(5):703-17. PubMed.

Further Reading

No Available Further Reading