Antibody

eIF2α phos (119A11)

Tools

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Clonality: monoclonal
Host: Rabbit
Isotype: iGg
Methods: IH, IP, WB
Source: Cell Signaling
Cat# 3597
O'Connor, 2008
Formulation: liquid, affinity purified, sodium HEPES, BSA, glycerol
Reactivity:
Reacts in: Human, Monkey, Mouse, Rat, Drosophila

Immunogen/Epitope

immunogen = synthetic peptide (KLH-coupled) derived from the carboxy terminal sequence of eIF2α.

Specificity

detects endogenous eIF2alpha only when phosphorylated at Ser51; does not recognize eIF2alpha phosphorylated at other sites

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References

Paper Citations

  1. . Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. Neuron. 2008 Dec 26;60(6):988-1009. PubMed.

Further Reading

No Available Further Reading