Antibody

EEA1 (14)

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Clonality: monoclonal
Host: Mouse
Isotype: IgG1
Methods: IF, WB
Source: BD Transduction
Cat# 610456/7
References:
Sanz-Clemente, 2010
Friedrich, 2010
Jiang Y., 2010
Vetrivel, 2008
Haque, 2008
(all, unspecified formulation)
Tampellini, 2007
Liu, 2007
Formulation: aqueous, buffered, BSA, azide, glycerol, purified
Reactivity:
Reacts in: Dog, Chicken, Human, Rat

Immunogen/Epitope

immunogen = Human EEA1, aa. 3-281

Specificity

180 kDa EEA1

Note

not IH, IP

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References

Paper Citations

  1. . Casein kinase 2 regulates the NR2 subunit composition of synaptic NMDA receptors. Neuron. 2010 Sep 23;67(6):984-96. PubMed.
  2. . Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1942-7. PubMed.
  3. . Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1630-5. PubMed.
  4. . Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts. J Biol Chem. 2009 Feb 6;284(6):3793-803. PubMed.
  5. . Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1716-21. PubMed.
  6. . Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations. J Biol Chem. 2007 Jun 29;282(26):18895-906. PubMed.
  7. . Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2223-8. PubMed.

Further Reading

No Available Further Reading