Antibody

Doublecortin (C-18)

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Clonality: polyclonal
Host: Goat
Isotype: IgG
Source: Santa Cruz
Cat# sc-8066
References:
Wang, J, 2010
Demars, 2010
(unspecified epitope)
Maier, 2008
Chumley, 2007
(but unspecified epitope)
Formulation: liquid IgG, affinity purified, PBS, azide, gelatin
Reactivity:
Reacts in: Human, Mouse, Rat

Immunogen/Epitope

immunogen = peptide mapping at the C-terminus of Doublecortin of human origin

Specificity

40 kDa doublecortin

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References

Paper Citations

  1. Wang JM, Singh C, Liu L, Irwin RW, Chen S, Chung EJ, Thompson RF, Brinton RD. Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6498-503. Epub 2010 Mar 15 PubMed.
  2. Demars M, Hu YS, Gadadhar A, Lazarov O. Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice. J Neurosci Res. 2010 Aug 1;88(10):2103-17. PubMed.
  3. Maier M, Peng Y, Jiang L, Seabrook TJ, Carroll MC, Lemere CA. Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice. J Neurosci. 2008 Jun 18;28(25):6333-41. PubMed.
  4. Chumley MJ, Catchpole T, Silvany RE, Kernie SG, Henkemeyer M. EphB receptors regulate stem/progenitor cell proliferation, migration, and polarity during hippocampal neurogenesis. J Neurosci. 2007 Dec 5;27(49):13481-90. PubMed.

Further Reading

No Available Further Reading