Antibody

CD11b /Mac-1α (M1/70)

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Clonality: monoclonal
Host: Rat
Isotype: IgG2b
Source: BD Pharmingen
Cat# 557672
Formulation: aqueous buffered solution, affinity purified, stabilizer, azide, Alexa Fluor® 488 conj.
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

immunogen = C57BL/10 mouse splenic T cells and concanavalin A-activated C57BL/10 splenocytes

Specificity

reacts with CD11b; reportedly blocks cell adherence and C3bi binding, but it does not block cell-mediated lysis. Cross-reaction of mAb M1/70 with CD11b on human monocytes, polymorphonuclear leukocytes, and NK cells has been reported

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