Antibody

Caspase-3, active

Tools

Back to the Top

Clonality: polyclonal
Host: Rabbit
Isotype: IgG
Methods: IH, WB
Source: R&D Systems
Cat# AF-835
Reference:
Nikolev, 2009
Formulation: affinity purified, filtered, PBS, trehalose, lyophilized
Reactivity:
Reacts in: Human, Mouse
other species not tested

Immunogen/Epitope

immunogen = KLH coupled synthetic peptide CRGTELDCGIETD corresponding to amino acids 163 - 175 of human Caspase 3

Specificity

detects the p17 subunit of Caspase 3 but does not detect or poorly detects the precursor form; can distinguish apoptotic cells from non-apoptotic cells as determined by IH and WB analysis of anti-Fas treated Jurkat cells and WB of staurosporine treated mouse 3T3 cells

Note

protocol available

Comments / Questions

Make a comment or submit a question

To make a comment you must login or register.

Comments on this content

No Available Comments

References

Paper Citations

  1. . APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature. 2009 Feb 19;457(7232):981-9. PubMed.

Further Reading

No Available Further Reading