Clonality: monoclonal
Host: Mouse
Source: BAP-15
(Manfred Brockhaus, F. Hoffmann-La Roche Ltd., Basel,
Paper)
Reference:
Richter L, 2010
Formulation: purified from spent hybridoma medium and conjugated to horseradish peroxidase
Reactivity:
Reacts in: Human

Immunogen/Epitope

immunogen = the peptide CGGVVIA conjugated
to keyhole limpet hemocyanin

Specificity

specific for Aβ42; no cross-reactivity observed with Ab39, Ab40 or Ab43. Ab41 showed a signal accounting for about 10% of the cognate Ab42 signal

Comments / Questions

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References

Paper Citations

1. Richter L, Munter LM, Ness J, Hildebrand PW, Dasari M, Unterreitmeier S, Bulic B, Beyermann M, Gust R, Reif B, Weggen S, Langosch D, Multhaup G. Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14597-602. PubMed.

External Citations

1. Paper

Further Reading

No Available Further Reading