Antibody

Aβ 42, C-terminus

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Clonality: monoclonal
Host: Mouse
Methods: ELISA, FA
Source: BAP-15
(Manfred Brockhaus, F. Hoffmann-La Roche Ltd., Basel,
Paper)
Reference:
Richter L, 2010
Formulation: purified from spent hybridoma medium and conjugated to horseradish peroxidase
Reactivity:
Reacts in: Human

Immunogen/Epitope

immunogen = the peptide CGGVVIA conjugated
to keyhole limpet hemocyanin

Specificity

specific for Aβ42; no cross-reactivity observed with Ab39, Ab40 or Ab43. Ab41 showed a signal accounting for about 10% of the cognate Ab42 signal

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References

Paper Citations

  1. . Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14597-602. PubMed.

External Citations

  1. Paper

Further Reading

No Available Further Reading