Antibody

Aβ 42

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Clonality: polyclonal
Host: Rabbit
Source: amyloid-beta R165
(Pankaj Mehta,
Department of Immunology, New York State Institute for Basic Research, Staten Island, New York)
References:
Chung, E, 2010
Schupf, 2008
Sigurdsson, 2001
Formulation: Sandwich ELISA
Reactivity:
reference:<br />Mehta P D, Dalton A J, Mehta S P, Kim K S, Sersen E A, Winiewski H M. Neurosci Lett 241:13-16, l998

Immunogen/Epitope

 

Specificity

amyloid-beta 42

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References

Paper Citations

  1. Chung E, Ji Y, Sun Y, Kascsak RJ, Kascsak RB, Mehta PD, Strittmatter SM, Wisniewski T. Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an Alzheimer's disease model mouse. BMC Neurosci. 2010;11:130. PubMed.
  2. Schupf N, Tang MX, Fukuyama H, Manly J, Andrews H, Mehta P, Ravetch J, Mayeux R. Peripheral Abeta subspecies as risk biomarkers of Alzheimer's disease. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14052-7. Epub 2008 Sep 8 PubMed.
  3. Sigurdsson EM, Scholtzova H, Mehta PD, Frangione B, Wisniewski T. Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice. Am J Pathol. 2001 Aug;159(2):439-47. PubMed.

External Citations

  1. Pankaj Mehta

Further Reading