Antibody

APP, C-term

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Clonality: polyclonal
Host: Rabbit
Methods: IC, IH, IP, WB
Source: Chemicon and Upstate are Millipore
cat# AB5352
References:
Muresan, 2009
Kim, 2007
Formulation: liquid, serum, PBS, azide
Reactivity:
Reacts in: Human, Monkey
other species not tested

Immunogen/Epitope

immunogen = nine aa peptide (Y K F F E Q M Q N) of APP C-terminal region

Specificity

full length APP, C-terminal. May react with APLP1 and APLP2.

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References

Paper Citations

  1. . The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites. J Neurosci. 2009 Mar 18;29(11):3565-78. PubMed.
  2. . BACE1 regulates voltage-gated sodium channels and neuronal activity. Nat Cell Biol. 2007 Jul;9(7):755-64. PubMed.

Further Reading

News

  1. San Diego: Exploring the Role of APP in Transit
  2. Brushing Up on APP—Mint-y Fresh Signaling Pathways Uncovered