Source: (Stefan Lichtenthaler, Adolf Butenandt Institute, Ludwig Maximilians University, München, Germany)
Reacts in: Human
immunogen = a peptide comprising amino acids 11–16 of the Aβ
specifically detects APPsα ending in amino acids 15 and 16 (APPs-15 and APPs-16), but does not detect shorter APPs species, including APPsβ' and APPsβ; does not detect full-length APP
- Kuhn PH, Wang H, Dislich B, Colombo A, Zeitschel U, Ellwart JW, Kremmer E, Rossner S, Lichtenthaler SF. ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons. EMBO J. 2010 Sep 1;29(17):3020-32. PubMed.
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