Antibody

Amyloid β [1-42]

Tools

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Clonality: kit
Host: Mouse
Methods: ELISA
Source: Innogenetics
cat# 80177
INNOTEST® ß- AMYLOID(1-42)
Also distributed by Autogen Bioclear
References:
Compta, 2010
Fagan, 2009
Buerger, 2009
Yan, 2009
Visser, 2009
Mattsson, 2009
Laske, 2008
Fagan, 2007
Reactivity:
Reacts in: Human
<em>not</em> reactive with other species

Immunogen/Epitope

Uses 21F12 as a capture antibody and incubation with biotinylated 3D6; 3D6 selectively binds Aß peptides with a free amino
group at Asp1 (epitope 1–5)

Specificity

amyloid beta (cerebrospinal fluid)

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References

Paper Citations

  1. . High cerebrospinal tau levels are associated with the rs242557 tau gene variant and low cerebrospinal β-amyloid in Parkinson disease. Neurosci Lett. 2011 Jan 7;487(2):169-73. PubMed.
  2. . Cerebrospinal fluid tau and ptau181 increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer's disease. EMBO Molecular Medicine. 2009 Nov 1;1(8-9):371-380.
  3. . Validation of Alzheimer's disease CSF and plasma biological markers: the multicentre reliability study of the pilot European Alzheimer's Disease Neuroimaging Initiative (E-ADNI). Exp Gerontol. 2009 Sep;44(9):579-85. PubMed.
  4. . Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice. J Neurosci. 2009 Aug 26;29(34):10706-14. PubMed.
  5. . Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study. Lancet Neurol. 2009 Jul;8(7):619-27. PubMed.
  6. . CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA. 2009 Jul 22;302(4):385-93. PubMed.
  7. . Inverse association of cortisol serum levels with T-tau, P-tau 181 and P-tau 231 peptide levels and T-tau/Abeta 1-42 ratios in CSF in patients with mild Alzheimer's disease dementia. Eur Arch Psychiatry Clin Neurosci. 2009 Mar;259(2):80-5. PubMed.
  8. . Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults. Arch Neurol. 2007 Mar;64(3):343-9. PubMed.

Further Reading

No Available Further Reading