Antibody

Amyloid β [1-40]

Tools

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Clonality: kit
Host: Unknown Host
Methods: ELISA
Source: Biosource Invitrogen
cat# KHB3481, 96 tests
cat#KHB3482, 192 tests
References:
Tampellini, 2009
He, 2009
Dong, 2008
Tampellini, 2007
Sagare, 2007
Van Uden, 2002
Formulation: colormetric kit, 4 member solid phase sandwich, Strip-well plates, precoated with anti-Hu Aβ mAb directed to NH2-terminus of the mature peptide, liquid stable conjugate, chromogen and stop reagents
Reactivity:
Reacts in: Human

Specificity

Recognizes both natural and recombinant human Aβ [1-40], in serum, cell culture and CSF. No cross with Aβ [1-12], [1-20], [12-28], [22-35], [1-42], [1-43], [42-1]

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References

Paper Citations

  1. . Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations. J Neurosci. 2009 Aug 5;29(31):9704-13. PubMed.
  2. . Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease. J Neurosci. 2009 May 20;29(20):6545-57. PubMed.
  3. . Corticosterone and related receptor expression are associated with increased beta-amyloid plaques in isolated Tg2576 mice. Neuroscience. 2008 Jul 31;155(1):154-63. PubMed.
  4. . Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations. J Biol Chem. 2007 Jun 29;282(26):18895-906. PubMed.
  5. . Clearance of amyloid-beta by circulating lipoprotein receptors. Nat Med. 2007 Sep;13(9):1029-31. PubMed.
  6. . Increased extracellular amyloid deposition and neurodegeneration in human amyloid precursor protein transgenic mice deficient in receptor-associated protein. J Neurosci. 2002 Nov 1;22(21):9298-304. PubMed.

Further Reading