Antibody
Amyloid beta[1-42]
Quick Links
Clonality: kit
Host: Unknown Host
Source: IBL
cat# 27711
References:
Kitazume, 2010
Hoe, 2009
Formulation: solid phase sandwich ELISA using 2 kinds of high specific antibodies, range of 12.5 pg/ml ~ 800 pg/ml. Precoated plate with Aβ(38-42) Rabbit IgG; labeled antibody Anti-Human Aβ(11-28) Mouse IgG
Reactivity:
Reacts in: Human
Specificity
quantitative determination of human A β (1-42) in cerebrospinal fluid, cell culture media or the extract from brain tissue, both recombinant and native forms of human Aβ(1-42)
References
Paper Citations
- Kitazume S, Tachida Y, Kato M, Yamaguchi Y, Honda T, Hashimoto Y, Wada Y, Saito T, Iwata N, Saido T, Taniguchi N. Brain endothelial cells produce amyloid {beta} from amyloid precursor protein 770 and preferentially secrete the O-glycosylated form. J Biol Chem. 2010 Dec 17;285(51):40097-103. PubMed.
- Hoe HS, Lee KJ, Carney RS, Lee J, Markova A, Lee JY, Howell BW, Hyman BT, Pak DT, Bu G, Rebeck GW. Interaction of reelin with amyloid precursor protein promotes neurite outgrowth. J Neurosci. 2009 Jun 10;29(23):7459-73. PubMed.
Further Reading
News
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- Keystone: Death Receptor Ligand—New Role for APP, New Model for AD? PAPER RETRACTED.
- Keystone: Partners in Crime—Do Aβ and Prion Protein Pummel Plasticity?
- Keystone: Longevity, Insulin-like Growth Factor Signaling, and Aβ Toxicity
- Keystone: Pulse-Chasing AD Biomarkers, Snaring γ-Secretase Targets
- Keystone: Tau, Huntingtin—Do Prion-like Properties Play a Role in Disease?
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