Antibody

Amyloid beta [1-42]

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Clonality: polyclonal
Host: Rabbit
Methods: ELISA, IH, WB
Source: Chemicon and Upstate are Millipore
Cat# AB5078P
References:
formulation?
Wang, J, 2010,
Tampellini, 2009
Muresan, 2009
Zaghi, 2009
Clifford, 2008
Zelcer, 2007
Formulation: liquid, tris, BSA, azide, affinity purified
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

immunogen = a 6 aa peptide sequence from the C-terminal of human β-amyloid 1-42.

Specificity

β-amyloid 1-42

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References

Paper Citations

  1. . Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6498-503. PubMed.
  2. . Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations. J Neurosci. 2009 Aug 5;29(31):9704-13. PubMed.
  3. . The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites. J Neurosci. 2009 Mar 18;29(11):3565-78. PubMed.
  4. . Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy. Acta Neuropathol. 2009 Feb;117(2):111-24. PubMed.
  5. . Alpha7 nicotinic acetylcholine receptor expression by vascular smooth muscle cells facilitates the deposition of Abeta peptides and promotes cerebrovascular amyloid angiopathy. Brain Res. 2008 Oct 9;1234:158-71. PubMed.
  6. . Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors. Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10601-6. PubMed.

Further Reading